Medicine for treating advanced non-small-cell lung cancer and preparation method of medicine

A non-small cell lung cancer and drug technology, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, can solve the problems of poor quality of life, cardiopulmonary and kidney function, high cost of immunotherapy, and the curative effect is yet to be evaluated. Inhibition of platelet aggregation, improvement of tumor blood coagulation disorder, and improvement of blood coagulation status

Active Publication Date: 2017-05-10
平阴县中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Non-small cell lung cancer accounts for about 80-85% of the total cases of lung cancer. Because the patients have no obvious symptoms in the early stage, 75% of the patients are already in the advanced stage when they go to the doctor, and the 5-year survival rate is less than 2%. The prognosis is extremely poor
Chemoradiotherapy is the first choice in the treatment of advanced

Method used

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  • Medicine for treating advanced non-small-cell lung cancer and preparation method of medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] A. Weigh 40 grams of Hedyotis diffusa, 40 grams of Banzhilian, 20 grams of Houttuynia cordata, 10 grams of tangerine peel, 30 grams of Trichosanthes, 10 grams of Coix seed, 30 grams of Tinglizi, 10 grams of Scutellaria baicalensis, Zhimu 20 grams, 10 grams of bitter almonds, 20 grams of Fritillaria, 20 grams of turtle shells, 20 grams of Prunella vulgaris, 20 grams of Astragalus, 20 grams of Codonopsis, 20 grams of reed root, 10 grams of peach kernels, 10 grams of perilla seeds, and 10 grams of roasted licorice gram spare;

[0058] B. Crush Fritillaria fritillata prepared in Step A into fine powder, pass through a 100-mesh sieve for later use; use Hedyotis diffusa, Banzhilian, Houttuynia cordata, Tangerine Peel, Trichosanthes, Coix Seed prepared in Step A . ratio), soak for 1 hour, heat to boiling and decoct for 1 hour, filter the decoction; add 2 times of water for the second time (weight ratio), heat to boiling and decoct for 1 hour, filter and extract the decoction,...

Embodiment 2

[0061] A. Weigh 30 grams of Hedyotis diffusa, 30 grams of Banzhilian, 30 grams of Houttuynia cordata, 20 grams of tangerine peel, 20 grams of Trichosanthes, 15 grams of Coix seed, 20 grams of Tinglizi, 15 grams of Scutellaria baicalensis, Anemarrhena anemarrhena 15 grams, 15 grams of bitter almonds, 20 grams of Fritillaria, 25 grams of turtle shells, 20 grams of Prunella vulgaris, 30 grams of Astragalus, 15 grams of Codonopsis, 20 grams of reed root, 15 grams of peach kernels, 10 grams of perilla seeds, and 10 grams of roasted licorice gram spare;

[0062] B. Crush Fritillaria fritillata prepared in Step A into fine powder, pass through a 100-mesh sieve for later use; use Hedyotis diffusa, Banzhilian, Houttuynia cordata, Tangerine Peel, Trichosanthes, Coix Seed prepared in Step A . ratio), soak for 1.5h, heat to boiling and decoct for 1.2h, filter the decoction; add water 3 times (weight ratio) for the second time, heat to boiling and decoct for 1.2h, filter and decoct, combi...

Embodiment 3

[0065] A. Weigh 20 grams of Hedyotis diffusa, 20 grams of Banzhilian, 40 grams of Houttuynia cordata, 20 grams of tangerine peel, 30 grams of Trichosanthes, 20 grams of Coix seed, 20 grams of Tinglizi, 20 grams of Scutellaria baicalensis, Anemarrhena anemarrhena 10 grams, 20 grams of bitter almonds, 10 grams of Fritillaria, 30 grams of turtle shells, 10 grams of Prunella vulgaris, 40 grams of Astragalus, 10 grams of Codonopsis, 10 grams of reed root, 20 grams of peach kernels, 15 grams of perilla seeds, and 5 grams of roasted licorice Gram is standby; All the other steps are with embodiment 2.

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Abstract

The invention discloses a medicine for treating advanced non-small-cell lung cancer and a preparation method of the medicine. The medicine for treating advanced non-small-cell lung cancer is prepared from raw materials in parts by weight as follows: 20-40 parts of hedyotis diffusa, 20-40 parts of scutellaria barbata, 20-40 parts of herba houttuyniae, 10-20 parts of dried tangerine peel, 20-30 parts of fructus trichosanthis, 10-20 parts of semen coicis, 20-30 parts of semen lepidii, 10-20 parts of radix scutellariae, 10-20 parts of rhizoma anemarrhenae, 10-20 parts of semen armeniacae amarae, 10-20 parts of bulbus fritillaria thunbergii, 20-30 parts of carapax trionycis, 10-20 parts of prunella vulgaris, 20-40 parts of radix astragali, 10-20 parts of codonopsis pilosula, 10-20 parts of rhizoma phragmitis, 10-20 parts of semen persicae, 10-15 parts of fructus perillae and 5-10 parts of radix glycyrrhizae preparata. The medicine has the effects of clearing heat, removing toxins, reducing phlegm, removing blood stasis, tonifying qi and nourishing yin and has functions of resisting tumor, relieving cough, eliminating phlegm and enhancing body immunity. The medicine capsules can relieve symptoms of patients, have exact curative effect and can prolong lifetime of the patients and improve the life quality.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a medicine for treating advanced non-small cell lung cancer and a preparation method thereof. Background technique [0002] The incidence of lung cancer ranks first in the global cancer. The incidence rate of lung cancer in my country is 46.08 per 100,000 people, and the mortality rate is obviously on the rise. It has become the first cause of cancer death. Non-small cell lung cancer is a type of lung cancer, which includes squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Compared with small cell carcinoma, the growth and division of its cancer cells are slower, and the diffusion and metastasis are relatively late. Non-small cell lung cancer accounts for about 80-85% of the total cases of lung cancer. Because the patients have no obvious symptoms in the early stage, 75% of the patients are already in the advanced sta...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P35/00A61K35/586
CPCA61K35/586A61K36/31A61K36/344A61K36/428A61K36/481A61K36/484A61K36/535A61K36/536A61K36/539A61K36/736A61K36/748A61K36/752A61K36/78A61K36/8964A61K36/8966A61K36/899A61K36/8994A61K2236/331A61K2236/39A61K2300/00
Inventor 孙兴亮杜峰王兴强李新张秀芝
Owner 平阴县中医医院
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