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Medicine composition for treating mammary glands hyperplasia diseases, and preparation method, preparation and application thereof

A technology of mammary gland hyperplasia and composition, which is applied in the field of medicine, can solve the problems of large adverse reactions, long course of disease, and easy recurrence, and achieve the effects of good safety, small toxic and side effects, and improved curative effect

Active Publication Date: 2017-05-31
KUNMING SINOWAY NATURAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the long course of the disease, it is easy to relapse, which seriously endangers the physical and mental health of women. At present, there is no ideal treatment method for pure western medicine. Complications, so traditional Chinese medicine is the main means of clinical treatment of mammary gland hyperplasia

Method used

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preparation example Construction

[0022] The preparation method of the pharmaceutical composition for the treatment of mammary gland hyperplasia described in the present invention comprises pretreatment, extraction, posttreatment steps, specifically comprises:

[0023] A. Pretreatment: crush and sieve the raw material Periplaneta americana with the formula ratio to obtain material a for later use; at the same time, cut the raw materials Moutan Cortex, Prunella vulgaris, Bupleurum, Sanleng and Curcuma zedoary into slices or segments and mix them to obtain Material b is reserved;

[0024] B. Extraction:

[0025] 1) adding ethanol solution to material a to extract and concentrate to obtain extract c;

[0026] 2) adding ethanol solution to material b to extract and concentrate to obtain extract d;

[0027] C. Post-processing: crush and sieve the extract c and extract d respectively, and mix them uniformly to obtain a pharmaceutical composition for treating mammary gland hyperplasia disease with the target substa...

Embodiment 1

[0049] The formula is 100 parts of Periplaneta americana; 60 parts of Cortex Moutan; 200 parts of Prunella vulgaris; 80 parts of Bupleurum; 150 parts of Sanleng;

[0050] (1) The preparation of the Periplaneta americana extract, the method and steps are as described above, and it is set aside.

[0051] (2) The preparation method of Moutan Cortex, Prunella vulgaris, Bupleurum, Sanleng, and Curcuma five-flavor herbal medicine extract:

[0052] a. Pre-treatment: Take the five medicinal materials of Moutan bark, Prunella vulgaris, Bupleurum, Sanleng, and Zedoary, remove impurities, slice or segment;

[0053] b. Extraction: take the slices of medicinal herbs cut in a, extract twice with 70% ethanol, add 6 times the amount of 70% ethanol for the first time, soak at room temperature for half an hour, then heat and reflux for 2 hours; 3 times the amount of 70% ethanol, heated to reflux for extraction for 1 hour. The extracts were collected, combined, and filtered to obtain an ethano...

Embodiment 2

[0058] The formula is 100 parts of Periplaneta americana; 150 parts of Cortex Moutan; 90 parts of Prunella vulgaris; 30 parts of Bupleurum; 60 parts of Sanleng;

[0059] (1) The preparation of the Periplaneta americana extract, the method and steps are as described above, and it is set aside.

[0060] (2) Preparation method of Moutan Cortex, Prunella vulgaris, Bupleurum, Sanleng, and Curcuma five-flavor herbal medicine extract

[0061] a. Pre-treatment: Take the five medicinal materials of Moutan bark, Prunella vulgaris, Bupleurum, Sanleng, and Zedoary, remove impurities, slice or segment;

[0062] b. Extraction: take the slices of medicinal herbs cut in a, extract them with 80% ethanol for 3 times, add 8 times the amount of 80% ethanol for the first time, soak at room temperature for half an hour, then heat and reflux for 3 hours; 5 times the amount of 80% ethanol, heated to reflux for extraction for 2 hours. The extracts were collected, combined, and filtered to obtain an ...

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Abstract

The invention discloses a medicine composition for treating mammary glands hyperplasia diseases, and a preparation method, a preparation and application thereof. The medicine composition for treating mammary glands hyperplasia diseases is prepared from the following raw materials in parts by weight: 50 to 150 parts of periplaneta americana, 60 to 200 parts of cortex moutan, 90 to 250 parts of spica prunellae, 30 to 150 parts of radix bupleuri, 60 to 150 parts of sparganium stoloni and 60 to 150 parts of rhizoma zedoariae, and is prepared from the steps of pretreatment, extraction and post treatment. According to the preparation, pharmaceutically acceptable auxiliary materials are added into the medicine composition for treating mammary glands hyperplasia diseases to be prepared into a tablet preparation, a capsule preparation, a granule preparation, a pill preparation and a combined preparation. The application refers to the application of the medicine composition for treating mammary glands hyperplasia diseases to the preparation of medicine for preventing / treating mammary glands hyperplasia diseases. The composition provided by the invention has the advantages that the curative effect on the mammary glands hyperplasia can be effectively improved; the use is convenient; the toxic and side effects are small; the safety is high; economic performance and practicability are realized; the medicine composition is worthy of being popularized and applied.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating mammary gland hyperplasia, a preparation method, preparation and application thereof. Background technique [0002] Mammary gland hyperplasia is a common and frequently-occurring disease in clinical women. The occurrence and development of this disease are related to endocrine disorders in patients. Benign hyperplasia of mammary glands, especially atypical breast epithelial hyperplasia, can increase the risk of breast cancer. Hyperplasia of mammary glands is characterized by lumps and pain in the breast. In my country, cystic changes are rare, and most of them are glandular hyperplasia, so they are often called "mammary gland hyperplasia". In Chinese medicine theory, mammary gland hyperplasia belongs to the category of "breast addiction". Hyperplasia of mammary glands accounts for more than 70% of all breast diseases, and it...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P15/14A61K35/64
CPCA61K35/63A61K36/233A61K36/536A61K36/65A61K36/71A61K36/902A61K36/9066A61K2236/15A61K2236/333A61K2300/00
Inventor 郝振平徐溧
Owner KUNMING SINOWAY NATURAL PHARMA
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