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Traditional Chinese medicine compound with skin whitening function and preparation method and application of traditional Chinese medicine compound

A functional and traditional Chinese medicine technology, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, skin care preparations, etc., can solve the problems of easy decomposition, large side effects, skin pigmentation, etc., to promote metabolism, lighten pigmentation, and effectively The effect of high content of ingredients

Inactive Publication Date: 2017-06-13
韩丰河
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] It has a strong whitening effect, but it is easy to decompose when exposed to light and heat. Whitening preparations containing chemical ingredients or heavy metals are easy to cause skin pigmentation after use
[0009] deposition, side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] 1. Raw materials of traditional Chinese medicine compound with whitening function: 3 parts of Galla charcoal, 3 parts of Cortex Phellodendri, and 3 parts of Comfrey.

[0049] 2. The preparation method of the Chinese medicine compound with whitening function:

[0050] First, take Galla carbs and fry for 20-30 minutes to get Galla carbs, take 3 parts galla carbs, 3 parts Phellodendron cortex and 3 parts comfrey

[0051] Parts were dried overnight in an oven, crushed and sieved through a 40-mesh sieve, set aside, then added water 7 times the amount of medicinal materials, heated and refluxed for 1 hour

[0052] , filter, add 3 times the amount of water to the filter residue, heat and reflux for extraction for 1 hour, combine the extracts, filter, take the filtrate, concentrate the medicinal solution, add 95% ethanol to make the ethanol concentration 70%, let it stand for precipitation, and take Concentrate the filtrate, add 0.2%-0.3% activated carbon, heat at 80-90°C for ...

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Abstract

The invention discloses a traditional Chinese medicine compound with skin whitening functions and a preparation method and application of the traditional Chinese medicine compound. The traditional Chinese medicine compound is prepared from the following raw materials in parts by weight: 3-10 parts of gallnut carbon, 3-10 parts of golden cypress and 3-10 parts of lithospermum. According to traditional Chinese medicine principles, the traditional Chinese medicine compound disclosed by the invention is prepared according to syndrome differentiation and treatment ideas, test results show that the traditional Chinese medicine compound disclosed by the invention has very good effects of inhibiting activity of tyrosinase, inhibiting generation of B16F10 cell melanin, inhibiting proliferation of B16F10 cells and promoting apoptosis of the B16F10 cells and has a definite skin whitening effect, and in addition, a traditional Chinese medicine compound extract is safe to use, free of toxic or side effect and stable in quality, can be prepared into multiple daily articles, and has the potential of being developed as a novel skin whitening preparation.

Description

technical field [0001] The invention relates to a compound Chinese medicine, in particular to a compound Chinese medicine with whitening function and a preparation method thereof [0002] and its application. Background technique [0003] The color of the skin mainly depends on the amount of melanin contained in the skin. Melanocytes in the epidermis [0004] Its synthesis is affected by various enzymes in the cell, including tyrosinase, dopachrome isomerase, 5,6-dioxindole-2-carboxylic acid (DHICA) oxidase, etc. Among them, tyrosinase is the main rate-limiting enzyme, and the activity of this enzyme determines the [0005] The number of elements formed. In addition, the synthesis of melanin is also affected by factors such as ultraviolet rays and free radicals. [0006] Most of the current whitening products mainly focus on inhibiting tyrosinase. These existing drugs, in terms of stability, side effects [0007] The use, effect and other aspects are not satisfactory....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/9789A61K36/756A61Q19/02A61Q19/08A61Q17/04A61P17/00A61P17/10A61K35/64
CPCA61Q17/04A61Q19/02A61Q19/08A61K8/97A61K8/98A61K35/63A61K36/30A61K36/756A61K2236/39A61K2236/53A61K2236/55A61K2236/51A61K2236/15A61K2236/331A61K2236/333A61Q19/10A61K2300/00
Inventor 韩丰河
Owner 韩丰河
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