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Menoxenia prevention and treatment traditional Chinese medicine composition preparation method

A technology of irregular menstruation and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc. It can solve the problem of difficulty in uniform particle density and size, difficulty in making tablets with low auxiliary materials, deep color of particles, etc. Problems, achieve the effect of shortening processing time and heating time, shortening processing time, and uniform particles

Inactive Publication Date: 2017-06-16
韩丰河
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AI Technical Summary

Problems solved by technology

The preparation method disclosed above adopts the wet granulation method, and the Chinese medicine extract needs to be concentrated into a thick extract, which is heated for a long time, and the resulting granules are generally darker in color, and the density and size of the granules are not uniform. Process tablet production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Boil Motherwort 24g, Rhizoma Cyperi 12g, Passepartout 12g, Ligusticum Chuanxiong 12g, Wang Buliuxing 12g, and Spatholobus Spatholobus 12g with water

[0066] Extracted 2 times, the first time the amount of water added was 10 times the amount of medicine, and the extraction time was 2 hours; 1.05 water-extracted extract; put dextrin or starch in the one-step granulator as a substrate, spray the above-mentioned water-extracted extract as a binder into the one-step granulator, open the air in and out, and control the - The negative pressure of 0.02MPa makes the powder boil evenly in the tank of the granulator, and then heat to control the temperature of the material at 30°C.

[0067] Carry out one-step granulation, and the granulation time is 5 hours; the granules made by one-step granulation are sized, and an appropriate amount of auxiliary material micro-powder silicon is added

[0068] Glue, dextrin, starch, microcrystalline cellulose, compressed into tablets.

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine composition for preventing and treating irregular menstruation. The method comprises the steps of extracting a certain amount and a certain composition of raw materials (Motherwort, Rhizoma Cyperi, Passepartout, Chuanxiong, and Wangbuliuxing) with water Concentrate into a water-extracted dilute extract, or use water extraction and alcohol precipitation to concentrate into a water-extracted alcohol-precipitated dilute extract; then, put dextrin or starch in a one-step granulator as a substrate, and dilute the above water-extracted extract Or water-extracted and alcohol-settled dilute extract is used as a binder and sprayed into a one-step granulator for one-step granulation; finally, the granules are sized, and other auxiliary materials are added to make a traditional Chinese medicine oral preparation. The method can significantly reduce the amount of auxiliary materials, shorten the processing time and the heating time for concentration and drying, avoid destroying the active ingredients of the traditional Chinese medicine composition, the produced granules have good fluidity, the compressed tablets disintegrate faster, and the process flow is simplified , reduces energy consumption, the production process is not easy to be polluted, and the quality of finished products is better guaranteed.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition, in particular to a traditional Chinese medicine combination for preventing and treating irregular menstruation [0002] method of preparation. Background technique [0003] Gynecological diseases--Irregular menstruation refers to the abnormality of menstrual cycle, menstrual period, menstrual volume, menstrual color, and menstrual quality, or it is accompanied by menstrual cycle [0004] Symptoms are characterized by gynecological diseases, including premenstrual period, late period, irregular menstruation, menorrhagia, dysmenorrhea, etc., as well as systemic symptoms such as headache, insomnia, and diarrhea caused by irregular menstruation. [0005] According to the survey and statistics of the Ministry of Health, the incidence rate of gynecological diseases in my country is as high as 75%, among which patients with irregular menstruation and dysmenorrhea are...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61P15/00
CPCA61K36/185A61K9/2059A61K36/236A61K36/36A61K36/533A61K36/8905A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 韩丰河
Owner 韩丰河
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