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Drug for lowering clinical side effects of dexamethasone acetate tablets

A technology of dexamethasone acetate and side effects, which is applied in the field of pharmaceuticals for reducing the clinical side effects of dexamethasone acetate tablets, and can solve problems such as unsatisfactory effects and large toxic and side effects

Inactive Publication Date: 2017-06-20
沂南县迎辉农业开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The treatment of this disease in modern medicine is mainly based on anti-inflammation, suppression of immune response, symptomatic treatment and supportive treatment, but the effect is not ideal, and the side effects are large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] The preparation of the present invention is made of component A and component B, and the component A is 3 mg of dexamethasone acetate tablet; component B includes 20 g of blue skyflower, 45 g of gallinaceous grass, 25 g of vine root, and red shin powder 30g, 50g Hetacao, first grind the dexamethasone acetate tablets into powder for later use; prepare the medicinal materials in component B, add an appropriate amount of water, first heat to boil with strong fire, then change to slow fire for half an hour, filter, and pour into Add powdered dexamethasone acetate tablets into the filtered medicinal solution, stir well and continue to heat with slow fire for 20 minutes to obtain the preparation of the present invention.

[0008] Toxicity test

[0009] 1. Experimental animals 44 clean-grade healthy SD female rats, with a body weight of (201±4) g, used for chronic toxicology experiments; 32 clean-grade healthy Kunming female mice, with a body weight of (22±2) g, used For acut...

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PUM

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Abstract

The invention discloses a drug for lowering clinical side effects of dexamethasone acetate tablets, belonging to the technical field of drugs. The drug is composed of a component A and a component B, wherein the component A is dexamethasone acetate tablets; and the component B is prepared from Nervilia fordii, Stellaria neglecta herb, Clematis grandidentata root, Polygonum runcinatum and Waltheria indica root and stem. The clinical test proves that the drug has favorable curative effects on ulcerative colitis, and obviously lowers the side effects.

Description

technical field [0001] The invention relates to the technical field of medicaments, in particular to a medicament for reducing the clinical side effects of dexamethasone acetate tablets. Background technique [0002] Ulcerative colitis, also known as chronic nonspecific ulcerative colitis or idiopathic ulcerative colitis, is a common chronic intestinal disease and a multifactorial, multilayered nonspecific inflammation of unknown cause. The lesions are mainly in the mucosa and submucosa of the colon, showing a continuous diffuse distribution, most of which involve the rectum and sigmoid colon. The main clinical manifestations are abdominal pain, diarrhea, mucus pus and blood in the stool, tenesmus, etc. Some patients have extraintestinal manifestations, such as joint, liver and bile duct diseases, and eye and skin damage; Between 20-50 years old, but no significant sex difference. The treatment modern medicine of this disease is mainly with anti-inflammation, suppresses im...

Claims

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Application Information

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IPC IPC(8): A61K31/573A61K36/898A61P1/00A61P1/04
CPCA61K31/573A61K36/185A61K36/36A61K36/704A61K36/716A61K36/898A61K2236/331A61K2300/00
Inventor 邱桂珍
Owner 沂南县迎辉农业开发有限公司
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