Digestive tract mucosa coloring agent and preparation method

Abstract

The invention discloses a digestive tract mucosa coloring agent and a preparation method, and relates to the technical field of digestive tract detection. The digestive tract mucosa coloring agent comprises the following raw materials in parts by weight: 85-92 parts of an indigo carmine aqueous solution with the mass fraction of 0.15-0.3% and 8-15 parts of a traditional Chinese medicine extracting solution. The traditional Chinese medicine extracting solution comprises the following raw materials in parts by weight: 20-30 parts of Radix Aucklandiae, 20-30 parts of malt, 20-30 parts of Fructus Litseae, 20-30 parts of Radix Linderae, 12-20 parts of Pericarpium Citri Reticulatae, 12-20 parts of Rhizoma Dioscoreae, 12-20 parts of Rhizoma Polygonati, 8-15 parts of Flos Caryophylli, 8-15 parts of Radix Angelicae Sinensis, 8-15 parts of Fructus Jujubae and 8-15 parts of Radix Glycyrrhizae. The coloring agent is further added with the traditional Chinese medicine extracting solution ingredients; the traditional Chinese medicine extracting solution has effects of promoting circulation of qi and stopping pain, invigorating the spleen and reinforcing the stomach, and promoting blood circulation and resisting bacteria; pain of a patient can be reduced; spasm of a digestive tract is reduced; clear color development is facilitated; and the digestive tract mucosa coloring agent has healthcare effect on the intestines and stomach of the patient.

Description

technical field

[0001] The invention relates to the technical field of digestive tract detection, in particular to a digestive tract mucous membrane stain and a preparation method. Background technique

[0002] The surface of the normal gastrointestinal mucosa is smooth, but when there are minor lesions, such as ulcers, cancer, etc., the surface will change, but in the early stage, the changes are very small, and it is difficult to find it under ordinary endoscopy. The dye uses the principle of contrast. When the dye is sprayed on the mucous membrane, the indigo carmine cannot deposit on the smooth surface, but all deposits between the grooves of the mucous membrane folds, forming a sharp contrast with the orange-red mucous membrane. The continuous lines show the subtle concave-convex changes of the mucosa and its three-dimensional structure, which is conducive to the early detection of tumors and other lesions that are not obvious under conventional endoscopy in clinical pr...

Examples

Embodiment 1

[0034] A digestive tract mucous membrane staining agent, comprising the following raw materials in parts by weight: 85 parts of indigo carmine aqueous solution with a mass fraction of 0.15% and 15 parts of a Chinese medicine extract, the Chinese medicine extract including the raw materials in the following parts by weight: Woody Fragrance 20 20 parts of malt, 30 parts of Litsea cubeba, 30 parts of Wuyao, 12 parts of tangerine peel, 12 parts of yam, 12 parts of sealwort, 15 parts of clove, 8 parts of angelica, 15 parts of jujube and 8 parts of licorice.

[0035] The Chinese medicine extract is prepared by the following steps:

[0036] Mix the raw materials and crush them to 100 meshes. After pretreatment: add 1 times the weight of water to the raw materials to wet them for 2 hours, then put them into a high-pressure tank, increase the pressure to 100Mpa within 2 minutes, keep the pressure for 15 seconds, and then quickly release the pressure to Atmospheric pressure; then add 8 ...

Embodiment 2

[0039] A digestive tract mucous membrane staining agent, comprising the following raw materials in parts by weight: 86 parts of indigo carmine aqueous solution with a mass fraction of 0.18% and 14 parts of Chinese medicine extract, the Chinese medicine extract comprising the following raw materials in parts by weight: woody 22 22 parts of malt, 28 parts of Litsea cubeba, 28 parts of black medicine, 14 parts of tangerine peel, 13 parts of Chinese yam, 13 parts of sealwort, 14 parts of clove, 9 parts of angelica, 14 parts of jujube and 9 parts of licorice.

[0040] The Chinese medicine extract is prepared by the following steps:

[0041] Mix the raw materials and crush them to 120 mesh. After pretreatment: add 1.5 times the weight of water to the raw materials to wet them for 1.5 hours, then put them into a high-pressure tank, increase the pressure to 105Mpa within 3 minutes, keep it for 14 seconds, and then release the pressure quickly to normal pressure; then add a 65% ethanol...

Embodiment 3

[0044] A digestive tract mucous membrane staining agent, comprising the following raw materials in parts by weight: 88 parts of indigo carmine aqueous solution with a mass fraction of 0.2% and 12 parts of Chinese medicine extract, the Chinese medicine extract comprising the following raw materials in parts by weight: Muxiang 24 24 parts of malt, 26 parts of Litsea cubeba, 26 parts of black medicine, 15 parts of tangerine peel, 14 parts of yam, 14 parts of sealwort, 13 parts of clove, 10 parts of angelica, 13 parts of jujube and 10 parts of licorice.

[0045] The Chinese medicine extract is prepared by the following steps:

[0046] Mix the raw materials and crush them to 140 mesh. After pretreatment: add 2 times the weight of water to the raw materials for wetting for 1 hour, then put them into a high-pressure tank, increase the pressure to 110Mpa within 4 minutes, keep it for 13 seconds, and quickly release the pressure to Atmospheric pressure; then add 70% ethanol solution wi...

technical field

[0001] The invention relates to the technical field of digestive tract detection, in particular to a digestive tract mucous membrane stain and a preparation method. Background technique

[0002] The surface of the normal gastrointestinal mucosa is smooth, but when there are minor lesions, such as ulcers, cancer, etc., the surface will change, but in the early stage, the changes are very small, and it is difficult to find it under ordinary endoscopy. The dye uses the principle of contrast. When the dye is sprayed on the mucous membrane, the indigo carmine cannot deposit on the smooth surface, but all deposits between the grooves of the mucous membrane folds, forming a sharp contrast with the orange-red mucous membrane. The continuous lines show the subtle concave-convex changes of the mucosa and its three-dimensional structure, which is conducive to the early detection of tumors and other lesions that are not obvious under conventional endoscopy in clinical pr...

Examples

Embodiment 1

[0034] A digestive tract mucous membrane staining agent, comprising the following raw materials in parts by weight: 85 parts of indigo carmine aqueous solution with a mass fraction of 0.15% and 15 parts of a Chinese medicine extract, the Chinese medicine extract including the raw materials in the following parts by weight: Woody Fragrance 20 20 parts of malt, 30 parts of Litsea cubeba, 30 parts of Wuyao, 12 parts of tangerine peel, 12 parts of yam, 12 parts of sealwort, 15 parts of clove, 8 parts of angelica, 15 parts of jujube and 8 parts of licorice.

[0035] The Chinese medicine extract is prepared by the following steps:

[0036] Mix the raw materials and crush them to 100 meshes. After pretreatment: add 1 times the weight of water to the raw materials to wet them for 2 hours, then put them into a high-pressure tank, increase the pressure to 100Mpa within 2 minutes, keep the pressure for 15 seconds, and then quickly release the pressure to Atmospheric pressure; then add 8 ...

Embodiment 2

[0039] A digestive tract mucous membrane staining agent, comprising the following raw materials in parts by weight: 86 parts of indigo carmine aqueous solution with a mass fraction of 0.18% and 14 parts of Chinese medicine extract, the Chinese medicine extract comprising the following raw materials in parts by weight: woody 22 22 parts of malt, 28 parts of Litsea cubeba, 28 parts of black medicine, 14 parts of tangerine peel, 13 parts of Chinese yam, 13 parts of sealwort, 14 parts of clove, 9 parts of angelica, 14 parts of jujube and 9 parts of licorice.

[0040] The Chinese medicine extract is prepared by the following steps:

[0041] Mix the raw materials and crush them to 120 mesh. After pretreatment: add 1.5 times the weight of water to the raw materials to wet them for 1.5 hours, then put them into a high-pressure tank, increase the pressure to 105Mpa within 3 minutes, keep it for 14 seconds, and then release the pressure quickly to normal pressure; then add a 65% ethanol...

Embodiment 3

[0044] A digestive tract mucous membrane staining agent, comprising the following raw materials in parts by weight: 88 parts of indigo carmine aqueous solution with a mass fraction of 0.2% and 12 parts of Chinese medicine extract, the Chinese medicine extract comprising the following raw materials in parts by weight: Muxiang 24 24 parts of malt, 26 parts of Litsea cubeba, 26 parts of black medicine, 15 parts of tangerine peel, 14 parts of yam, 14 parts of sealwort, 13 parts of clove, 10 parts of angelica, 13 parts of jujube and 10 parts of licorice.

[0045] The Chinese medicine extract is prepared by the following steps:

[0046] Mix the raw materials and crush them to 140 mesh. After pretreatment: add 2 times the weight of water to the raw materials for wetting for 1 hour, then put them into a high-pressure tank, increase the pressure to 110Mpa within 4 minutes, keep it for 13 seconds, and quickly release the pressure to Atmospheric pressure; then add 70% ethanol solution wi...