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Cistanche extract composition with effect of obviously relieving physical fatigue and preparation method thereof

A technology for relieving physical fatigue and cistanche, applied in drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of many quality control indicators, unguaranteed efficacy, and many raw materials, so as to reduce serum urea levels, Increase liver glycogen reserves and relieve fatigue

Inactive Publication Date: 2017-08-29
新疆旺源生物科技集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the deficiencies and existing problems of the current state of the art, especially the traditional Chinese medicine compound that has the effect of relieving physical fatigue needs more raw materials, many quality control indicators, and the bottleneck problem that the efficacy cannot be guaranteed, the present invention provides a method for significantly relieving physical fatigue. The effective Cistanche extract composition and its preparation method. Compared with the prior art, the method is to carry out ethanol solution reflux extraction on Cistanche tuberosum, Acanthopanax and Epimedium respectively, and concentrate under reduced pressure to prepare the extract. Through the preparation process Control the content of the key ingredients in the Cistanche tuberosa extract, Epimedium extract, especially the Acanthopanax extirgae extract for relieving physical fatigue, and form an extraction composition in proportion, the extraction composition includes Cistanche tuberculosis extract 90 Servings - 150 servings, Acanthopanax extract 100 servings - 170 servings, Epimedium extract 80 servings - 110 servings

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1: The extract composition that significantly relieves physical fatigue

[0022] The Cistanche extract composition significantly relieving physical fatigue provided by the present invention comprises 90-150 parts of the extract of Cistanche cistanche, the total phenylethanol glycosides in the extract of Cistanche tuberosa >40.0%, and 100-170 parts of the extract of Acanthopanax acanthopanax Parts, eleutheroside B1&C>0.8% in Acanthopanax extract, 80-110 parts in Epimedium extract, icariin>8.0% in Epimedium extract.

[0023] Preferably, the Cistanche extract composition that significantly relieves physical fatigue provided by the present invention includes 120 parts of Cistanche tubulosa extract, 40.0% of the total phenylethanol glycosides in the Cistanche tubulosa extract, 135 parts of Acanthopanax acanthopanax extract, and Eleutheroside B1&C>0.8% in Radix Acanthopanax extract, 95g of Epimedium extract, and icariin>8.0% in Epimedium extract.

Embodiment 2

[0024] Example 2: Preparation of Cistanche Herba Extract Composition for Significant Alleviation of Physical Fatigue

[0025]The Cistanche deserticola extract composition provided by the present invention significantly relieves physical fatigue, and the preparation method specifically adopts the following technical steps:

[0026] (1) Preparation of Cistanche tuberosa extract: take Cistanche tuberosa, remove impurities and mildew, etc., clean and select, dry and pulverize through a 40-mesh dryer, feed the material, add 70%-10-12 times the volume of Cistanche tuberose 80% ethanol solution, reflux extraction twice, each time for 1h, filter, combine the two extracts, and concentrate under reduced pressure at a vacuum degree of 0.07MPa-0.08MPa and a temperature of 60°C-65°C to obtain an extract, and the extract obtained in a vacuum The temperature is 0.07MPa-0.08MPa, the temperature is 60°C-65°C, vacuum-dried until the water content is lower than 5%, and then pulverized to obtain ...

Embodiment 3

[0031] Take Cistanche tuberosa, remove impurities and mildew, etc., and then dry and pulverize it through a 40-mesh dryer, feed the material, add 70% ethanol solution of 10 times the volume of Cistanche tuberose, reflux extraction twice, each time for 1h, filter, The two extracts were combined, concentrated under reduced pressure at a vacuum degree of 0.07MPa and a temperature of 60°C to obtain an extract, and the obtained extract was vacuum-dried at a vacuum degree of 0.07MPa and a temperature of 60°C until the water content was lower than 5%, and then pulverized to obtain tube flowers Cistanche deserticola extract, after testing the total phenylethanol glycosides in the Cistanche deserticola tuberosa extract > 40.0%, set aside; take Acanthopanax senticosus, remove impurities and mildew, etc., after cleaning, dry and pulverize through a 40-mesh dryer, feed, add medicinal materials 10- 14 times the volume of 40% ethanol solution, reflux extraction twice, each time for 1h, filte...

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PUM

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Abstract

The invention discloses a cistanche extract composition with the effect of obviously relieving the physical fatigue and a preparation method thereof. A traditional Chinese medicine extract is prepared from 90 to 150 parts of cistanche tubulosa wight extracts, 100 to 170 parts of eleutherococcus senticosus extracts and 80 to 110 parts of epimedium brevicornum extracts, wherein the content of phenylethanoid glycosides in the cistanche tubulosa wight extracts is greater than 40.0 percent; the content of eleutheroside B1 and C in the eleutherococcus senticosus extracts is greater than 0.8 percent; the icariin in the epimedium brevicornum extracts is greater than 8.0 percent. Functional experiments prove that the physical fatigue relieving efficiency of the composition prepared by compounding the eleutherococcus senticosus extracts with the eleutheroside B1 and C reaching the standard, the cistanche tubulosa wight extracts and the epimedium brevicornum extracts can be obviously improved, and the action is even better than that of the eleutheroside B and E; the mouse loading swimming time can be obviously prolonged; the mouse hepatic glycogen storage quantity is increased; the serum urea level after mouse movement is reduced; the mouse fatigue is relieved; the effect is better than that of the single use of the cistanche tubulosa wight extracts.

Description

technical field [0001] The invention belongs to the technical field of preparation of traditional Chinese medicines, and more specifically, the invention relates to the technical field of a Cistanche deserticola extract composition and a preparation method thereof. Background technique [0002] With the rapid development of social economy, people are facing more and more work pressure, and they are prone to body fatigue. Body fatigue is a phenomenon in which the working ability of tissues, organs and the whole body is temporarily reduced when the individual's activities reach a certain level. If the body fatigue accumulates for a long time and cannot be eliminated, it will develop into excessive fatigue, which will cause pathological changes in certain organs of the body and endanger the health of the human body. . At present, protecting the immune function of the body and preventing free radical damage are the new focus of current fatigue research, and the application of t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/64A61P39/00
CPCA61K36/254A61K36/296A61K36/64A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 卿德刚倪慧孙宇张娟陈刚粮徐晓琴徐建国贾晓光
Owner 新疆旺源生物科技集团有限公司
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