Chickpea composition with effect of increasing bone density and application

A technology for increasing bone density and chickpeas, applied in the field of chickpea compositions, can solve problems such as unsatisfactory effects, and achieve the effects of being convenient to carry and eat, promoting calcium absorption, and having high safety.

Inactive Publication Date: 2017-10-03
新疆丝路弘毅农业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Intestinal Ca 2+ Malabsorption is one of the important causes of osteoporosis, vitamin D 3 Can promote intestinal response to Ca 2+ and can promote the reabsorption of calcium by the kidneys. Studies have shown that taking calcium or vitamin D alone is often not effective in preventing primary senile osteoporotic fractures. Therefore, sufficient calcium and vitamin D are important for maintaining bone health. It is very necessary for the best treatment effect of osteoporosis

Method used

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  • Chickpea composition with effect of increasing bone density and application
  • Chickpea composition with effect of increasing bone density and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A chickpea composition with the effect of increasing bone density, the composition is made of the following raw materials in parts by weight: 974 parts by weight of chickpeas, 26 parts by weight of calcium citrate, vitamin D 3 15×10 -6 parts by weight.

[0027] Crush and sieve: Take the chickpeas and grind them through a 200-mesh sieve, mix calcium citrate and vitamin D 3 Pass through a 120-mesh sieve and set aside.

[0028] Blend: Combine chickpea flour, calcium citrate, and vitamin D 3 Mix well and serve.

Embodiment 2

[0029] Example 2 Pharmacological Experiments of Increasing Bone Mineral Density

[0030] The composition of Example 1 was used as the test sample.

[0031] Test objects and feeding management: SD female rats, 250-290g, feeding temperature and humidity: 20-25 ℃, 40-70%, using 12 h: 12 h day and night lighting; free to eat and drink.

[0032] Grouping and dose setting: After surgical modeling, the rats were adaptively fed for one week, and the rats were randomly divided into model groups, high-dose, medium-dose, and low-dose groups according to body weight, with 10 rats in each group. Another 10 normal rats were used as blank control group. In addition, a middle-dose group (0.4 g / kg) and a low-dose group (0.2 g / kg) were respectively set up, and the drugs were given by intragastric administration for 3 months.

[0033] Data analysis: All the data in this experiment were expressed as mean ± standard deviation (), and the difference analysis between groups was performed by SPSS 1...

Embodiment 3

[0045] Example 3 Preparation of Bone Density-Increasing Composition Biscuits

[0046] A chickpea composition biscuit with the effect of increasing bone density, the composition is made of the following raw materials in parts by weight:

[0047] The composition is made of the following raw materials in parts by weight: 970 parts by weight of chickpeas, 30 parts by weight of calcium citrate, vitamin D 3 10×10 -6 parts by weight.

[0048] Its preparation process comprises the following steps:

[0049] Crush and sieve: Take the chickpeas and grind them through a 300-mesh sieve, mix calcium citrate and vitamin D 3 Pass through a 100-mesh sieve and set aside.

[0050] Blend: Combine chickpea flour, calcium citrate, and vitamin D 3 Mix evenly to obtain the bone density-increasing composition mixture powder of chickpeas.

[0051] Cake making: Take chickpea bone density increasing composition mixed powder 300g, flour 153.8g, cornstarch 23.5g, egg 40g, maltitol 200g, edible oil 20...

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Abstract

The invention discloses a chickpea composition with an effect of increasing bone density and an application. The composition comprises chickpea, calcium citrate and vitamin D3. The composition has the effects of improving calcium metabolism level and activity of alkaline phosphatase of a rat model with osteoporosis, increasing weight of shaft of femur, increasing bone calcium content and the like. The composition provided by the invention can be used for preparing food, healthcare food or medicines capable of increasing bone density.

Description

technical field [0001] The invention relates to a chickpea composition, in particular to the bone density-increasing effect of the chickpea composition and its application in food, health food or medicine. Background technique [0002] Osteoporosis is a metabolic disease characterized by decreased bone mass and degeneration of bone tissue microstructure, resulting in increased bone fragility and increased fracture risk. It is common in the elderly. Currently, there are patients with osteoporosis (including osteopenia ) 84 million, accounting for 6.6% of the total population, and will more than double by 2050, reaching 210 million, accounting for 13.2% of the total population. With the aging of the population in China, osteoporosis has become a major social problem, seriously affecting the health and life expectancy of the elderly. The commonly used drugs for the treatment of osteoporosis mainly include estrogen drugs, which have obvious side effects and are associated with ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P19/10A61P19/08A23L33/155A23L33/105A61K31/194A61K31/593
CPCA23V2002/00A61K31/593A61K33/06A61K36/48A61K2300/00A23V2200/306
Inventor 严群超陈有军李杰
Owner 新疆丝路弘毅农业科技有限公司
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