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A traditional Chinese medicine oral liquid for treating children with sore throat and preparation method thereof

A technology for oral liquid of traditional Chinese medicine and sore throat, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc. It can solve problems such as complicated taking methods, inconvenient carrying, and difficulty in treating diseases. Achieve the effect of simple preparation process, convenient transportation and carrying, and good stability

Active Publication Date: 2021-04-02
SHENZHEN NEPTUNUS PHARMA RES INST CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The folks use the whole herb as medicine, and the method of taking it is complicated. There are strict requirements on the decoction utensils, decoction water, decoction heat, decoction time, special decoction method, etc., and it is inconvenient to carry.
In addition, traditional Chinese medicine decoctions mainly obtain the active ingredients through boiling, which is difficult to obtain, and the active ingredients cannot be used in a targeted manner, and its absorption efficiency cannot be guaranteed, so it is difficult to promote on a large scale, which causes certain difficulties in the treatment of diseases
[0008] At present, there is no report on the research and development of the prescription of disinfection powder, and there is no similar prescription on the market.

Method used

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Examples

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preparation example Construction

[0041] Specifically, a preparation method for simultaneously extracting the Chinese medicine extract and volatile oil of "Disinfection Powder", the medicinal materials are calculated in parts by weight, comprising the following steps:

[0042] 1) Take 6 parts of burdock fruit, 2 parts of nepeta panicle, and 1 part of licorice, roughly crush them, put them in a multi-functional extraction tank, add 8-15 times of water to extract for 1-3 hours, and extract for 1-3 times to obtain the extract and volatile oils;

[0043] 2) Add 0.1% to 0.3% of the oily carrier by weight of medicinal materials into the volatile oil receiver, collect the volatile oil obtained in step 1), and obtain a mixture of volatile oily carrier;

[0044] 3) The extract in the collection step 1) is further concentrated under reduced pressure to a volume that is 8-12 times the weight ratio of the original medicinal material;

[0045] 4) Dissolve the extract obtained in step 3) with water to a concentration of 0....

Embodiment 1

[0046] Embodiment 1: Preparation of a kind of oral liquid for treating sore throat in children

[0047] (1) Components

[0048] Disinfectant essential oil 3g

[0049] Tween 80 6g

[0050] Glycerin 8g

[0051] Sanitizer Powder Extract 195g

[0052] Macrogol 400 125g

[0053] Sorbic acid 1g

[0054] Stevia 2g

[0055] Orange Flavor 3ml

[0056] Pure water Add water to 1000ml.

[0057] (2) Preparation method

[0058] ① Disinfection powder volatile oil, Tween 80 and glycerin are mixed in a certain proportion and stirred evenly. Under continuous stirring at 25°C, water is added drop by drop at a rate of 1ml / min to form a clear drug-containing microemulsion; ② Add polyethylene glycol Add 400 to an appropriate amount of water and stir to dissolve, add the sterilized powder extract, stir until completely dissolved, add sorbic acid, stevioside, and orange essence and mix well; ③Add the solution in step 2 to the volatile oil microemulsion, and stir evenly , add water to the fu...

Embodiment 2

[0059] Embodiment 2: Preparation of a kind of oral liquid for treating sore throat in children

[0060] (1) Components

[0061] Disinfectant essential oil 1g

[0062] Polyoxyethylene hydrogenated castor oil 3g

[0063] Propylene glycol 2g

[0064] Sanitizer Powder Extract 65g

[0065] Macrogol 6000 30g

[0066] Parabens 1.5g

[0067] Sucralose 1g

[0068] Cantaloupe Flavor 4ml

[0069] Pure water add water to 1000ml

[0070] (2) Preparation method

[0071] ① Disinfectant volatile oil, polyoxyethylene hydrogenated castor oil and propylene glycol are mixed in a certain proportion and then stirred evenly. Under continuous stirring at 25 degrees, water is added drop by drop at a speed of 1ml / min to form a clear drug-containing microemulsion; Add ethylene glycol 6000 to an appropriate amount of water and stir to dissolve, add the disinfectant powder extract, stir until completely dissolved, add paraben, sucralose, and cantaloupe essence and mix well; ③ Add the solution in st...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine oral liquid for treating infant throat swelling and pain and a preparation method thereof. The traditional Chinese medicine oral liquid is prepared from the following components of disinfectant volatile oil, disinfectant extract, an emulsifier, a co-emulsifier, a co-solvent, a preservative, and a flavoring agent. The preparation method comprises the following steps of (1) mixing the disinfectant volatile oil, the emulsifier and the co-emulsifier according to a certain ratio, uniformly stirring, gradually dripping water in the continuous stirring process at constant temperature, and forming a clear medicine-containing micro-emulsion; (2) adding the co-solvent into a proper amount of water, stirring and dissolving, adding the disinfectant extract, simultaneously stirring until complete dissolving, adding the preservative and the flavoring agent, and uniformly mixing; (3) adding the solution in step 2 into the volatile oil micro-emulsion, uniformly stirring, adding water to the whole amount, uniformly stirring, filtering, filling, and sterilizing, so as to obtain the traditional Chinese medicine oral liquid. Compared with the traditional Chinese medicine decoction, the traditional Chinese medicine oral liquid for treating the infant throat swelling and pain has the advantages that the administration is convenient, the mouth feel is good, the quality is stable, and the carrying is convenient.

Description

technical field [0001] The invention relates to a traditional Chinese medicine oral liquid of the classical Chinese medicine compound "Dudu San" and a preparation method thereof. Background technique [0002] Xiaodusan is an ancient prescription specially for children with sore throat. Jue" has been included in many classic medical books. [0003] The prescription of disinfection powder contains three kinds of medicinal materials; Burdock Seed (6 taels), Schizonepeta (2 taels), and Licorice (1 taels). The effects of each medicinal material are: [0004] 1) Arctium: evacuate wind-heat, clear away heat and detoxify rash, clear lung and relieve throat swelling; [0005] 2) Schizonepeta ear: relieve exterior wind, tonify rash, eliminate sores; [0006] 3) Licorice root: nourishing qi and invigorating the middle, nourishing the lungs and relieving cough, purging fire and detoxifying, coughing and asthma, sore throat. [0007] The ancient prescription of disinfection powder, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K9/107A61K36/538A61K47/44A61K47/26A61K47/10A61P11/04
CPCA61K9/0095A61K9/1075A61K36/28A61K36/484A61K36/538A61K47/10A61K47/26A61K47/44A61K2300/00
Inventor 王丽丽王志国崔婧杨经安谭道鹏卢禁
Owner SHENZHEN NEPTUNUS PHARMA RES INST CO LTD