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Equipment for the production of radiopharmaceuticals including lancing devices

A radiopharmaceutical, radioisotope technology used in the field of synthesizing radiolabeled compounds

Active Publication Date: 2020-07-31
GE HEALTHCARE LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for some radiochemical procedures, more than 5 reagent vials are required
Also, if it is desired to produce multiple batches of radiopharmaceuticals from a single cassette, additional capacity is required

Method used

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  • Equipment for the production of radiopharmaceuticals including lancing devices
  • Equipment for the production of radiopharmaceuticals including lancing devices
  • Equipment for the production of radiopharmaceuticals including lancing devices

Examples

Experimental program
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Embodiment Construction

[0014] In order to more clearly and concisely describe and refer to the claimed subject matter, definitions of specific terms used throughout the specification and claims are provided below. Any exemplification of specific language herein should be considered a non-limiting example.

[0015] A "system for the production of a radiopharmaceutical" is an apparatus configured to automate the synthesis of a radiolabeled compound suitable for use as an in vivo diagnostic agent. The system is suitably manufactured from pharmaceutical grade and radioactive breakdown resistant materials. A drug suitable for mammalian administration (i.e., sterile, non-pyrogenic) and for use as an in vivo imaging agent (i.e., the active pharmaceutical material is of sufficient purity and remains sufficiently radioactive to permit clinically useful imaging) should be obtained. Targeted system design for radiopharmaceutical preparation. Those skilled in the art of preparing radiopharmaceuticals will be ...

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Abstract

The present invention provides a system for producing a radiopharmaceutical comprising a radiosynthesis device and a disposable cassette. The system of the present invention includes means that allow the release of positions on the cartridge to include additional vials of reagents. With the system of the present invention, a wide range of radiochemical syntheses can be envisioned using the cassette.

Description

technical field [0001] The present invention relates to the synthesis of radiolabeled compounds. In particular, the invention relates to methods for the automated synthesis of radiolabeled compounds, especially where those compounds are suitable for use in radiopharmaceutical preparations. Background technique [0002] Radiolabeled compounds for use as in vivo imaging agents are currently typically prepared with the aid of automated synthesis equipment (alternatively "radio synthesizers"). Such automated synthesis equipment is commercially available from several suppliers, including: GE Healthcare; CTI Corporation; Ion Beam Applications AG (Chemin duCyclotron 3, Leuven-Nouveau, Belgium), B-1348; Raytest (Germany) and Bioscan (USA) . Radiochemistry is performed in a "cassette" or "cassette" designed to be removably and interchangeably fitted to the device such that mechanical movement of the moving parts of the device controls the operation of the cassette. Suitable casset...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01J19/00A61K51/04A61K101/02
CPCA61K51/0491B01J19/004B01J19/0093B01J2219/00867B01J2219/00792B01J2219/00833B01J2219/00894B01J2219/00927B01J2219/00916B01J2219/00952B01J2219/0095B01J2219/00799B01J2219/00862B01J2219/00918C07H5/02A61K51/0474B01J19/18C07B2200/05
Inventor X.弗兰奇P.杜蒙特S.利尼翁A.M.朗格N.弗布鲁格
Owner GE HEALTHCARE LTD
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