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Bacillus coagulans preparation and application thereof

A technology of Bacillus coagulans and preparations, applied in the field of microecological preparations, can solve problems such as no research reports, and achieve the effects of improving memory and attention, regulating spirit, and promoting nutrient absorption

Inactive Publication Date: 2018-01-23
QINGDAO EASTSEA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The inventors have found through research that Bacillus coagulans DH156 has high biological activity, and the microecological preparation containing Bacillus coagulans DH156 as the main active ingredient can effectively regulate the microecological balance of the body, prevent or treat related diseases, and is safe without any toxic and side effects. Huge economic value and social value, and no relevant research reports, hereby apply for this invention patent

Method used

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  • Bacillus coagulans preparation and application thereof
  • Bacillus coagulans preparation and application thereof
  • Bacillus coagulans preparation and application thereof

Examples

Experimental program
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preparation Embodiment 1

[0029] Preparation Example 1 The preparation of bacillus coagulans powder

[0030] 1 Preparation of bacteria powder and identification of strains

[0031] Take samples of human feces, soil, haystack substrate, etc., and then put the samples in a sterilized bottle, take 2 grams of the sample and add it to 18mL of sterilized diluent, mix well, and carry out 10 -1 、10 -2 、10 -3 、10 -4 , 10 -5 , 10 -6 , 10 -7 Gradient dilution, take 10 -5 , 10 -6 , 10 -7 Three dilution gradients, spread on the solid medium for selective single colony isolation of Bacillus coagulans, place in an incubator, culture at 37°C for 48 hours, select a single colony with good growth and inoculate it into the liquid expansion medium of Bacillus coagulans , expanded at 37°C for 48 hours. After the obtained culture solution is centrifuged (12000rpm) to separate the thalline, the thalline is freeze-dried in vacuum to prepare dry bacterial powder, and the number of viable bacteria is 1×10 10 CFU / g o...

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Abstract

The invention relates to a micro-ecological preparation and the application thereof, and specifically relates to a micro-ecological preparation containing bacillus coagulans as a main active ingredient and application of the preparation in prevention or treatment of relating diseases.

Description

technical field [0001] The invention relates to a microecological preparation and its application, in particular to a microecological preparation whose main active ingredient contains bacillus coagulans, and the application of the preparation in preventing or treating related diseases. Background technique [0002] Bacillus coagulans has the characteristics of high temperature resistance, acid resistance and bile salt resistance. It can improve the structure of intestinal flora, regulate intestinal dysfunction and maintain the balance of intestinal flora, effectively promote the metabolism and utilization of nutrients, and play a role in the prevention and treatment of diseases. play an increasingly important role. At present, Bacillus coagulans has passed the review of the Health and Family Planning Commission and has become a new probiotic species that can be used in food, and the research on Bacillus coagulans preparations has become a new hot spot. Screening Bacillus co...

Claims

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Application Information

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IPC IPC(8): A61K35/742C12N1/20A23L33/135A23K10/18A61P29/00A61P37/08A61P39/00A61P37/04A61P1/14A61P25/00A61P17/16A61P1/16A61P11/00A61P1/00A61P25/28A61P3/04A61P3/02A61P9/00A61P39/02A61P35/00C12R1/07
Inventor 崔云龙赵婀姿李洪福
Owner QINGDAO EASTSEA PHARMA
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