Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A detection method of traditional Chinese medicine composition for treating chronic pharyngitis

A technology for chronic pharyngitis and detection methods, which is applied in the direction of drug combinations, pharmaceutical formulas, measuring devices, etc., and can solve the problems of unfavorable manufacturers and supervision departments for overall product quality control and inability to control quality

Active Publication Date: 2020-08-18
滨州医学院附属医院
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The above-mentioned granules do not have relevant methods for testing them, so their quality cannot be controlled, and it is also not conducive to the overall control of product quality by manufacturers and supervisory departments.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A detection method of traditional Chinese medicine composition for treating chronic pharyngitis
  • A detection method of traditional Chinese medicine composition for treating chronic pharyngitis
  • A detection method of traditional Chinese medicine composition for treating chronic pharyngitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Prepare the granule for the treatment of chronic pharyngitis, its specific preparation method is as follows:

[0042] Weigh 300g Scrophulariaceae, 200g Shegan, 200g Platycodon grandiflorum, 200g Radix Paeoniae Rubra, 100g Chrysanthemum, 100g Licorice, add 10 times the total weight of the above medicinal materials and decoct three times, decoct for 2 hours for the first time, and combine the decoction , filtered, and the filtrate was allowed to stand for 12 hours;

[0043] The supernatant is concentrated to a relative density of 1.32 to 1.35, and the relative density is 80 to 85° C.; the clear paste is taken, sucrose and dextrin are added, granulated and dried to obtain granules.

Embodiment 2

[0045] The content of 4 kinds of compositions in the granule of embodiment 1 is measured simultaneously by HPLC method

[0046] Shimadzu LC-2010CHT high performance liquid phase (Shimadzu, Japan); 1 / 100,000 analytical balance (SHIMADZUAUW120D, Japan); digital constant temperature water bath (Danrui HH-D4);

[0047]Acetonitrile (Fisher scientific); phosphoric acid (analytical grade, Sinopharm Group); water (wahaha pure water); sheganoside (batch number: 222041, Aladdin reagent), luteolin, cinnamic acid, irisaxanthin (batch number: SBJ- I0601, SBJ-I0901, SBJ-I0201, Nanjing Senbega Biotechnology Co., Ltd.) the purity of the reference substance is greater than 98%; Yanshu granules are self-made in the preparation room of the Pharmacy Department of the Affiliated Hospital of Binzhou Medical College (batch numbers: 161206, 161212, 161217) .

[0048] Chromatographic column: THERMO Hypersil GOLD C18 chromatographic column (4.6×250mm 5μm);

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a detection method of a traditional Chinese medicine composition for treating chronic pharyngitis. The detection method of the traditional Chinese medicine composition for treating the chronic pharyngitis comprises a step of determining contents of tectoridin, luteolin, cinnamic acid and tectorigenin by a HPLC method. According to the detection method of the traditional Chinese medicine composition for treating the chronic pharyngitis disclosed by the invention, a quality standard of a new preparation can be effectively and strictly formulated; according to a relationship of assistance and guidance, contents of effective ingredients of the traditional Chinese medicine in the preparation are determined, and an experimental research on stability in vitro on the preparation is carried out, so that a good foundation is laid for researching and developing new medicines.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a detection method of a traditional Chinese medicine composition for treating chronic pharyngitis. Background technique [0002] Chronic pharyngitis is called "slow throat paralysis" in traditional Chinese medicine, and it is also called "throat paralysis of yin deficiency" and "throat paralysis of deficiency fire" in some books. TCM syndrome differentiation is divided into: deficiency of lung and kidney yin, deficiency of fire and inflammation; weakness of spleen and stomach, loss of nourishment in the throat; deficiency of spleen and kidney yang, loss of warmth in the throat; phlegm coagulation and blood stasis, accumulation of throat. [0003] Chronic pharyngitis is chronic inflammation of pharyngeal mucosa, submucosal and lymphoid tissues. According to the severity of the disease, the disease can be divided into chronic simple ph...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/02A61K36/88A61K9/16A61P11/04
CPCA61K9/1652A61K36/287A61K36/346A61K36/484A61K36/65A61K36/71A61K36/808A61K36/88A61K2236/331A61K2236/39A61K2236/51A61K2236/53G01N30/02A61K2300/00
Inventor 张金杰樊其忠孙迎东吕文文
Owner 滨州医学院附属医院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com