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Artery drug eluting stent based on 3D printing technology and preparation method thereof

A technology of eluting stents and 3D printing, applied in the field of vascular stents, can solve the problems of potential generation, microthrombosis, uneven stent surface, etc., and achieve the effect of good flexibility and ductility

Inactive Publication Date: 2018-03-23
GENERAL HOSPITAL OF PLA
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, the surface of traditional coated stents is very rough, and when implanted in the body, electric potential and microthrombus can be generated locally.

Method used

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  • Artery drug eluting stent based on 3D printing technology and preparation method thereof
  • Artery drug eluting stent based on 3D printing technology and preparation method thereof
  • Artery drug eluting stent based on 3D printing technology and preparation method thereof

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Embodiment Construction

[0039] Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments may, however, be embodied in many forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of example embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and thus their detailed descriptions will be omitted.

[0040] The embodiment of the present invention provides an arterial drug-eluting stent based on 3D printing technology. Of course, those skilled in the art should understand that this stent technology can also be transformed and applied to cardiovascular, peripheral blood vessels, nerve conduits, intestines, and bile ducts. , urethral and bone repair / reconstruction applications, etc.

[0041] In the arterial drug-eluting sten...

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Abstract

The invention relates to an intravascular stent technology, and discloses an artery drug eluting stent based on the 3D printing technology and a preparation method thereof. The stent comprises a plurality of stent beams, and a stent body is made of metal materials; seen from the section of the stent, the stent comprises a solid structure body and a drug carrying body of a porous structure, the drug carrying body is located on the side, facing the vascular wall, of the stent, the drug carrying body comprises a surface layer on the outer surface and the internal porous structure, the surface layer is provided with a plurality of release holes, and the stent body is integrally formed through the 3D printing technology. By applying the stent, restenosis and stent thrombosis caused by the defect of the stent technology can be effectively avoided, the 3D printing technology can achieve the stent metal porous structural design, and the innovative thinking of drug carrying inside the stent canbe completed.

Description

technical field [0001] The present invention generally relates to a vascular stent technology, in particular to a novel arterial drug-eluting stent based on 3D printing technology and a preparation method thereof. Background technique [0002] Since 1987, when Sigwart et al. used intravascular metal stents for coronary arteries for the first time, it has provided a good way for the treatment of vascular occlusion diseases. However, in-stent restenosis and in-stent thrombosis have always affected the The main reason for the efficacy of percutaneous coronary intervention (PCI). The main mechanism of in-stent restenosis is the hyperplasia of vascular intima and the delay of vascular endothelialization. Therefore, the prevention and treatment of in-stent restenosis is mainly to promote the rapid repair of vascular endothelium and inhibit the excessive proliferation of smooth muscle cells. [0003] The drug-eluting stent (DES) widely used clinically carries drugs through the pol...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/90B33Y10/00B33Y80/00A61M31/00
CPCA61F2/90A61M31/002B33Y10/00B33Y80/00
Inventor 白静王禹彭亮樊明浩张文勇梅建峰金昕冯宏启
Owner GENERAL HOSPITAL OF PLA
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