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Composition for treating ulcerative colitis and preparation method and application thereof

A technology for ulcerative colitis and composition, which is applied in the field of composition for treating ulcerative colitis, can solve problems such as long treatment time, and achieve the effects of low risk of side effects, few ingredients of raw materials, and strong pertinence

Active Publication Date: 2018-04-06
DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Another technical problem to be solved by the present invention is to overcome the long treatment time of the composition for treating ulcerative colitis in the prior art

Method used

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  • Composition for treating ulcerative colitis and preparation method and application thereof
  • Composition for treating ulcerative colitis and preparation method and application thereof
  • Composition for treating ulcerative colitis and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Embodiment 1 enema liquid

[0074] The composition for the treatment of ulcerative colitis of the present embodiment, its formula is as follows:

[0075] Sophora flavescens 15g, Qingdai 5g, Burnet charcoal 30g and gallnut 10g.

[0076] Select raw materials according to the above weight, mix Sophora flavescens, Indigo Daisy, Burnet charcoal and Galla gall to prepare granules; mix granules and water at a mass ratio of 1:4, stir evenly, and obtain an enema.

Embodiment 2

[0077] Embodiment 2 enema liquid

[0078] The composition for the treatment of ulcerative colitis of the present embodiment, its formula is as follows:

[0079] Sophora flavescens 15g, Qingdai 10g, Burnet charcoal 32g and gallnut 12g.

[0080] Select raw materials according to the above weight, mix Sophora flavescens, Indigo Daisy, Burnet charcoal and Galla gall to prepare granules; mix granules and water at a mass ratio of 1:3, stir evenly, and obtain an enema.

Embodiment 3

[0081] Example 3 Granules

[0082] The composition for the treatment of ulcerative colitis of the present embodiment, its formula is as follows:

[0083] Sophora flavescens 15g, Qingdai 5g, Burnet charcoal 27g and gallnut 7g.

[0084] The composition is prepared into granules according to the following steps:

[0085] Select raw materials according to the above weight, mix Sophora flavescens, Indigo Daisy, Burnet charcoal and Galla chinensis, wash and moisten thoroughly, add 10 times the mass of water, heat to boiling, boil for 3-4 hours, separate the decocted liquid, Repeat the above method for decocting the dregs for 2 to 3 times, combine the decocted liquid, centrifuge, take the supernatant, concentrate it into a thick paste, spray dry the thick paste to obtain a dry paste, mix the dry paste with excipients (such as dextrin) , sucrose) are mixed, ethanol is added as a binder, granulated and dried to obtain granules.

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Abstract

The invention discloses a composition for treating ulcerative colitis and a preparation method and an application thereof. Raw material medicines of an enema liquid include the following raw materialsin parts by weight: 15-20 parts of sophora flavescens, 5-10 parts of indigo naturalis, 27-32 parts of carbonized sanguisorba root and 7-12 parts of gallnuts. The composition for treating ulcerative colitis, provided by the invention, is prepared into granules, pills, capsules, suppositories or enema liquids, is directly acted to the affected part, and is good in treatment effect and high in curative effect in ulcerative colitis. Meanwhile, the raw material medicines are few in component, so that the risk of side effects of medicines is greatly reduced.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a composition for treating ulcerative colitis, a preparation method and application thereof. Background technique [0002] Colitis refers to inflammatory lesions of the colon caused by various reasons. The main clinical manifestations are diarrhea, abdominal pain, mucus and bloody stools, tenesmus, and even constipation, constipation within a few days, often accompanied by weight loss and fatigue, etc., often recurrent. According to different etiologies, colitis can be divided into ulcerative colitis, ischemic colitis, pseudomembranous colitis and so on. [0003] Most of the current medicines for treating colitis are western medicines, such as mesalamine, but their prices are high, and long-term use will bring certain side effects, such as mild stomach pain if taken for a long time, and chronic hepatitis may be induced. Traditional Chinese medicine has s...

Claims

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Application Information

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IPC IPC(8): A61K36/739A61P1/00A61P1/04A61K35/64
CPCA61K35/63A61K36/195A61K36/315A61K36/489A61K36/704A61K36/739A61K2236/331A61K2300/00
Inventor 李军祥
Owner DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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