Liquid eye dressing, preparation method of liquid eye dressing and liquid eye dressing product

An eye and liquid technology, applied in the field of liquid eye dressing, liquid eye dressing products, and its preparation field, can solve the problems of liquid leakage and the incision cannot be closed by itself, so as to reduce leakage, block bacterial infection, vision recovery speed effect

Active Publication Date: 2018-04-13
SAIKE SAISI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Cataract surgery can lead to acute endophthalmitis. Endophthalmitis is difficult to predict and is the most troublesome thing for ophthalmologists. The incidence of the syndrome has a certain relationship with the reconstruction of the wound. It is related to factors such as changes in intraocular pressure, but for postoperative trauma in eye surgery, there is currently no method that can effectively seal the wound and avoid fluid leakage

Method used

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  • Liquid eye dressing, preparation method of liquid eye dressing and liquid eye dressing product
  • Liquid eye dressing, preparation method of liquid eye dressing and liquid eye dressing product
  • Liquid eye dressing, preparation method of liquid eye dressing and liquid eye dressing product

Examples

Experimental program
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Effect test

Embodiment 1

[0059] This embodiment provides a liquid eye dressing, which comprises:

[0060] Powder: modified polyethylene glycol (2-arm-PEG-SPA, weight average molecular weight 3000, 0.15g), containing 0.1% of medical dye;

[0061] Solution: sodium tetraborate buffer solution (pH=8, 1 ml) containing polyethyleneimine (weight average molecular weight 2000, 10 g / L) and dithiothreitol (12.5 mmol / L).

[0062] This embodiment also provides a liquid eye dressing product, which is prepared according to the following preparation method: take 0.15 g of modified polyethylene glycol in a powder box, which is powder; weigh 10 g of polyethylene glycol Dissolve imine and 1.93g dithiothreitol in 1L sodium tetraborate buffer to make a solution with pH=8, and take 1ml and fill it in a solution bottle, which is the solution; after preparing a medical sponge swab, seal the package and sterilized.

[0063] How to use the liquid eye dressing product: Open the package, add the solution to the powder, stir e...

Embodiment 2

[0065] This embodiment provides a liquid eye dressing, which comprises:

[0066] Powder: modified polyethylene glycol (2-arm-PEG-SPA, weight average molecular weight 3000, 0.15g), containing 0.1% of medical dye;

[0067] Solution: sodium tetraborate buffer solution (pH=8, 1 ml) containing polyethyleneimine (weight average molecular weight 2000, 10 g / L) and dithiothreitol (35 mmol / L).

[0068] This embodiment also provides a liquid eye dressing product, which is prepared according to the following preparation method: take 0.15 g of modified polyethylene glycol in a powder box, which is powder; weigh 10 g of polyethylene glycol Dissolve imine and 5.39g dithiothreitol in 1L sodium tetraborate buffer to make a solution with pH=8, and take 1ml and fill it in a solution bottle, which is the solution; after preparing a medical sponge swab, seal the package and sterilized.

[0069] How to use the liquid eye dressing product: Open the package, add the solution to the powder, stir eve...

Embodiment 3

[0071] This embodiment provides a liquid eye dressing, which comprises:

[0072] Powder: modified polyethylene glycol (2-arm-PEG-SS, weight average molecular weight 3000, 0.15g), containing 0.1% of medical dye;

[0073] Solution: sodium tetraborate buffer solution (pH=8, 1 ml) containing polyethyleneimine (weight average molecular weight 2000, 10 g / L) and dithiothreitol (12.5 mmol / L).

[0074] This embodiment also provides a liquid eye dressing product, which is prepared according to the following preparation method: take 0.15 g of modified polyethylene glycol in a powder box, which is powder; weigh 10 g of polyethylene glycol Dissolve imine and 1.93g dithiothreitol in 1L sodium tetraborate buffer to make a solution with pH=8, and take 1ml and fill it in a solution bottle, which is the solution; after preparing a medical sponge swab, seal the package and sterilized.

[0075] How to use the liquid eye dressing product: Open the package, add the solution to the powder, stir ev...

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Abstract

A liquid eye dressing, a preparation method of the liquid eye dressing and a liquid eye dressing product relate to the field of medical materials. The liquid eye dressing comprises, by weight, 5-30% of powder and 70-95% of a solution; the powder includes modified polyethylene glycol; the solution is a buffered solution containing polyethyleneimine, dithiothreitol and tri-L-lysine; the liquid eye dressing product comprises the powder and the solution separately packaged, and medical sponge swabs for stirring and application. The powder and the solution are stirred well with the medical sponge swabs, and curing is allowed for 10-30 s. The process is simple; the liquid eye dressing prepared herein is suitable for eye surgeries, especially eye wounds after cataract surgery; surgical time can be shortened, vision recovery speed is increased, and no feeling of foreign objects is caused after using; an antibacterial barrier is formed at the surgical part, inflammations are decreased, leakagecan be decreased, bacterial infections can be blocked, pain is eased, and better comfort is provided for a patent's eyeballs.

Description

technical field [0001] The invention relates to the field of medical materials, and in particular to a liquid eye dressing, a preparation method thereof and a liquid eye dressing product. Background technique [0002] In ophthalmic surgery, the postoperative incision is mainly treated with sutures. The suture process requires time and skill. At the same time, traditional ophthalmic sutures will cause corneal wounds, and sutures may cause infection and affect the formation of new blood vessels. Prolong the healing time and easily cause eye inflammation and discomfort. [0003] Cataract is the leading cause of blindness in the world (Brian G, Taylor H. Cataract blindness-challenges for the 21 st century[J].Bull Word Health Orange,2001,79(3):249-256), and also the first blinding eye disease in my country (Li Dexin, Wang Siling, Su Desen, Pathogenesis and drug treatment of cataract[J]. Journal of Shenyang University of Science and Technology, 2002,19(4):300-307). There are ab...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0019A61L26/008C08L71/02C08L79/02
Inventor 董芳芳赵艳赵成如邓凤娟孔凡照苑康见王炜李正强
Owner SAIKE SAISI BIOTECH CO LTD
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