Application of NFI transcription factors in esophageal squamous cell carcinoma
A technology of esophageal squamous cell carcinoma and transcription factors, applied in the field of biomedicine
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[0039] The present invention studies the clinicopathological data of patients with squamous cell carcinoma of the esophagus who have received surgical treatment, and uses immunohistochemistry (IHC) in the immunoassay method to observe the effects of NFIA and NFIB in cancer tissues and paracancerous tissues of patients with squamous cell carcinoma of the esophagus. Combined with the clinicopathological data and follow-up data of these patients, the relationship between the expression of NFIA and NFIB in esophageal squamous cell carcinoma and the clinicopathological characteristics and prognosis of patients was discovered for the first time.
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[0041] The term "marker", "molecular marker" or "biomarker" refers to a molecule that is a target for analysis of a test sample of an individual. In one embodiment, examples of such molecular targets are proteins or polypeptides. Proteins or polypeptides used as markers in the present in...
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