Hernia patch fixing nail and preparation method thereof

Abstract

The invention relates to the technical field of absorbable biological materials and medical devices, in particular to a hernia patch fixing nail. The hernia patch fixing nail is obtained through injection molding of an absorbable biological material, the absorbable biological material is a blend formed by a composition of a heterogeneous polymer, the blend comprises, by molar ratio, 70-90% of lactide and 30-10% of glycolide; the preparation method of the hernia patch fixing nail comprises the steps that a general molecular weight and low molecular weight of rich lactide and rich glycolide arefirstly prepared, then melt mixing, dyeing, prilling, drying, injection molding and annealing are carried out in sequence to obtain the fixing nail. The prepared fixing nail has excellent comprehensive properties such as high strength, good toughness, strong resistance to heat deformation and high dimensional stability in the early stage and the initial stage of application; degradation is in a continuous state when carried out, the polymer is significantly degraded in an important period of internal tissue recovery and adjustment and is basically absorbed by the human body within 10-20 months; mixing is simple and the synthesis cost is low.

Description

technical field [0001] The invention relates to the technical field of absorbable biomaterials and medical devices, in particular to a hernia patch fixing nail and a preparation method thereof. Background technique [0002] A hernia is when a part of a human tissue or organ leaves its original location and enters another through a gap, defect or weakness in the body. The general incidence of hernia is 1% to 4%, and the male is 10 times that of the female, and mainly occurs on both sides, mostly in children and the elderly. If the hernia is not treated in time, it will be extremely harmful. The only way to cure hernia is surgical treatment. Hernia surgery is one of the most common and the largest number of operations in surgery. [0003] The existing treatment methods mainly include the following: 1) Traditional hernia repair surgery is to forcibly draw the two ends of the defect together with sutures to repair the defect. There is tension, which does not conform to the phys...

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Problems solved by technology

[0003] The existing treatment methods mainly include the following: 1) Traditional hernia repair surgery is to forcibly draw the two ends of the defect together with sutures to repair the defect. There is tension, which does not conform to the physiological condition and is more likely to recur; but the disadvantage is that the surgical incision Large, postoperative patient pain, long recovery time, need to be hospitalized for about 7 days, prone to defects such as intestinal adhesion, debilitating vitality, etc., not suitable for infants, young children, elderly and infirm, and patients with high blood pressure, heart disease, diabetes, etc.

2) Tissue mesh hernia surgery is currently considered a reasonable surgical method. This surgery has been carried out for more than 20 years at home and abroad. It conforms to human physiological anatomy. Artificial mesh plugs are used to fill abdominal wall defects and covered with mesh. The repair is reliable and tension-free , there is no stretching feeling at the surgical site after surgery, and there is little pain; but the disadvantages are open surgery, long operation time, high requirements for doctors' operation skills, slow recovery of patients, non-absorbable patch sutures, and high recurrence rate

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