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A kind of acne essence

An essence and anti-acne technology, which can be used in pharmaceutical formulations, cosmetic preparations, cosmetics, etc., and can solve problems such as affecting appearance and difficulty in treatment

Active Publication Date: 2021-06-15
广州科玛生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These problems not only seriously affect the appearance, but also have certain difficulties in treatment.

Method used

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  • A kind of acne essence
  • A kind of acne essence
  • A kind of acne essence

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～10

[0029] Examples 1-10 are examples of the acne-removing essence of the present invention, and the formulas of the acne-removing essence described in Examples 1-6 are shown in Table 1. The formula of the anti-acne essence described in Examples 7-10 is shown in Table 2. In Examples 1-10, the parts by weight of each component in the acne-removing composition A are: 15 parts of Salvia root extract, 3 parts of clove flower bud extract, 2 parts of Scutellaria baicalensis root extract, 2 parts of Angelica root extract, licorice 1 part of root extract and 1 part of Centella asiatica extract; the parts by weight of the components in the acne-removing composition B are: 3 parts of Hedyotis diffusa extract, 3 parts of Honeysuckle extract and 1 part of Acacia japonica seed extract share.

[0030] The preparation method of the anti-acne essence described in Examples 1-10 comprises the following steps:

[0031] S1. Homogenize carbomer and water with a hanging homogenizer until they are eve...

Embodiment 11

[0045] Product Safety Evaluation (Human Skin Patch Test)

[0046] 1. Test product: the anti-acne essence prepared in Examples 1-10 and Comparative Examples 1 and 2

[0047] Number of subjects: 120, female

[0048] Age: between 12 and 30 years old

[0049] Health status: The subjects have healthy skin, no history of allergies to skin diseases, and meet the voluntary selection criteria for subjects.

[0050] Grouping: 12 groups, 10 people in each group, with an average age of 25±2 years old.

[0051] 2. Patch method: select a qualified patch tester, drop about 0.020g ~ 0.025g of the test substance into the patch tester in a closed patch test method, and stick the special tape for external use on the back of the subject, 24 After 1 hour, the test substance was removed, and the skin reaction was observed at 0.5, 6, 12, 24, and 48 hours after removal, and the results were recorded according to the skin reaction grading standard in the "Hygienic Standards for Cosmetics".

[0052...

Embodiment 12

[0054] Bacteriostatic effect test

[0055] 1. Test materials

[0056] 1. Test strain: Propionibacterium acnes (ATCC6919).

[0057] 2. Test samples: according to S1, S2, S3, S4, S5, S6, S7, S8, S9, D1, D2 samples, store them at 4°C for later use, among which S1, S2, S3, S4, S5, S6, S7, S8 , S9, D1, D2 respectively correspond to the proportioning of the acne-removing ingredients in Examples 1-9 and Comparative Examples 1,2.

[0058] 3. Culture medium: Propionibacterium acnes medium, adjust the pH to 6.6-7.0. Add agar 15g / L to the solid medium.

[0059] 2. Test method

[0060] 1. Preparation and inoculation of the bacterial suspension: Take 0.1 mL of the frozen preserved bacterial suspension and put it in 5 mL of Propionibacterium acnes liquid medium, and culture it under anaerobic conditions at 37°C for 2 days to obtain the experimental bacterial suspension.

[0061] 2. Preparation of medicinal solution: Dilute S1, S2, S3, S4, S5, S6, S7, S8, S9, D1, and D2 with normal sali...

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Abstract

The invention discloses an acne-removing essence, which comprises an acne-removing composition A; the acne-removing composition A includes an extract of salvia miltiorrhiza root, an extract of clove flower buds, an extract of scutellaria baicalensis root, an extract of angelica root, and an extract of licorice root and Centella Asiatica Extract. According to the present invention, by adding mild plant extracts and cooperating with basic raw materials, the anti-acne essence is prepared, which can adjust the water-oil balance of the skin, remove acne, dilute acne marks, repair damaged skin, and restore the natural healthy state of the skin.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to an acne-removing essence. Background technique [0002] With the development of the economy and the continuous improvement of the quality of life, the awareness of acne treatment in Chinese acne patients has increased year by year. According to the joint survey results of China Dermatology Association and China Youth Federation, the incidence of acne in my country is on the rise year by year. More than 80% of young people have encountered the problem of acne to varying degrees. More than 1 / 3. [0003] Acne is a common name for acne, also known as "acne", "acne" or "acne", it is a skin disease caused by blockage and inflammation of hair follicles and sebaceous glands. During puberty, hormones in the body will stimulate hair growth and promote the sebaceous glands to secrete more oil, so the hair and sebaceous glands accumulate a lot of substances. Because this sympt...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61Q19/00A61Q17/00A61P17/10
CPCA61K2800/5922A61K2800/782A61Q17/005A61Q19/00A61Q19/008A61K8/9789A61P17/10
Inventor 何志青
Owner 广州科玛生物科技股份有限公司
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