Compound medicament as well as preparation method and application of compound medicament
A technology of compound medicine and main medicine, applied in the directions of pharmaceutical formula, antibacterial medicine, medicine combination, etc., can solve the problems of aggravation of disease, increase of cow culling rate, difficult treatment, etc., to promote distribution and absorption, and improve drug bioavailability , the effect of easy operation
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[0036] The present invention also provides a preparation method of the above-mentioned compound medicament, comprising the following steps:
[0037] Mix the main drug, stabilizer and solvent evenly, and dissolve the main drug and auxiliary materials to obtain a clear solution;
[0038] Mix the antioxidant, synergist and suspending agent with the clarified solution and stir well;
[0039] Afterwards, grind for 20-50 minutes in a colloid mill to obtain the finished product.
[0040] The steps of the preparation method are simple and easy to operate, and have the characteristics of quickness, convenience, low cost and strong operability.
Embodiment 1
[0168] The compound medicament of embodiment 1 has best therapeutic effect, and this is relevant with the selection type of adjuvant and vehicle. The selected auxiliary materials and solvents have the effect of enhancing the efficacy of the antibacterial agent, can promote the absorption of the agent and improve the efficacy of the agent.
[0169] The compound medicament of the present invention can be used for treating clinical mastitis of cows caused by Escherichia coli, Staphylococcus, Streptococcus and drug-resistant strain MRSA during lactation.
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