Application of phloretin to preparation of colitis preventing and treating drug

A technology of colitis and phloretin, which is applied in the field of application of phloretin in the preparation of drugs for the prevention and treatment of colitis, and can solve the problems that glucocorticoids are easy to cause obesity, patients are difficult to maintain long-term treatment, and adverse reactions are prone to occur , to achieve no adverse reactions and side effects, improve the pathological damage of colonic tissue, and reduce the effect of disease activity index
CN109364048AInactive Publication Date: 2019-02-22XINXIANG MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
XINXIANG MEDICAL UNIV
Publication Date
2019-02-22
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses an application of phloretin to preparation of an ulcerative colitis preventing and treating drug. According to the application of phloretin to the ulcerative colitis preventingand treating drug, the phloretin can prevent and treat ulcerative colitis, has no adverse reactions or side effects and has a maintained effect.
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Description

technical field

[0001] The invention relates to the field of biopharmaceuticals, in particular to the application of phloretin in the preparation of drugs for preventing and treating colitis. Background technique

[0002] Ulcerative colitis (UC) is a chronic non-specific intestinal disease of unknown cause. The lesions are mainly located in the mucosal layer of the colon, often involving the rectum and distal colon, and can also spread throughout the colon, showing continuous diffusion. sex distribution. The disease is seen at any age, and is more common in the age of 25-40. Except for a few patients with sudden onset, most patients have a slow onset, and the severity of the disease varies. Abdominal pain, diarrhea, mucus and bloody stools, and tenesmus were the main clinical symptoms. Histopathological manifestations were submucosal edema, inflammatory cell infiltration, decreased goblet cells, and decreased number of crypts. Endoscopic colon showed erosions, ulcers, and o...

Claims

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