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A compound traditional Chinese medicine and its application in the treatment of benign prostatic hyperplasia

A technology of prostatic hyperplasia and compound traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve problems such as obvious side effects and few varieties, and achieve the effect of treating prostatic hyperplasia

Active Publication Date: 2021-06-25
林嗣松 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] To sum up, in the current treatment methods for BPH, surgical treatment is prone to complications; there are not many varieties available for drug treatment, and the effective α1-ARs antagonists and 5-ARIs have obvious side effects, which have a negative effect on sexual function. There are different degrees of influence, and with the acceleration of the aging process, the number of BPH patients in all countries in the world is on the rise

Method used

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  • A compound traditional Chinese medicine and its application in the treatment of benign prostatic hyperplasia
  • A compound traditional Chinese medicine and its application in the treatment of benign prostatic hyperplasia
  • A compound traditional Chinese medicine and its application in the treatment of benign prostatic hyperplasia

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Effect test

Embodiment 1

[0025] Chinese medicinal materials: 50g of Rauwolfia, 200g of Epimedium, 200g of Tongkat Ali, 200g of Cornus officinalis, 100g of cinnamon, and 100g of chives.

[0026] Pulverize and mix the above-mentioned Chinese medicinal materials to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extract, get compound Chinese medicine extract 12.56g (hereinafter referred to as product A); Wherein, extraction pressure is 26MPa, and extraction temperature is 55 ℃, CO 2 The flow rate is 50L / h, the extraction time is 90min, the temperature of the separation tank I is 45°C, and the pressure is 8MPa, and the temperature of the separation tank II is 40°C, and the pressure is 5MPa.

Embodiment 2

[0028] Chinese medicine decoction pieces: 200g of Rauwolfia, 500g of Epimedium, 500g of Tongkat Ali, 500g of Cornus officinalis, 500g of cinnamon, and 500g of chives.

[0029] Pulverize and mix the above-mentioned Chinese medicinal pieces to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extraction, get Chinese medicine extract 41.12g (hereinafter referred to as product B); Wherein, extraction pressure is 30MPa, and extraction temperature is 50 ℃, CO 2 The flow rate is 60L / h, the extraction time is 60min, the temperature of the separation tank I is 40°C, and the pressure is 10MPa, and the temperature of the separation tank II is 35°C, and the pressure is 6MPa.

Embodiment 3

[0031] Chinese medicinal materials: 50g of Rauwolfia, 100g of Epimedium, 100g of Tongkat Ali, 100g of Cornus officinalis, 100g of Cinnamon, 100g of Chives.

[0032] Pulverize and mix the above-mentioned Chinese medicinal materials to obtain the material; add it to the extraction kettle, and use supercritical CO 2 Extraction, get Chinese medicine extract 7.52g (hereinafter referred to as product C); Wherein, extraction pressure is 28MPa, and extraction temperature is 53-55 ℃, CO 2 The flow rate is 55L / h, the extraction time is 70min, the temperature of the separation tank I is 43-45°C, and the pressure is 9MPa, and the temperature of the separation tank II is 38-40°C, and the pressure is 6MPa.

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Abstract

The invention relates to a compound Chinese medicine and its application in treating benign prostatic hyperplasia. The compound Chinese medicine comprises the following raw materials in proportion by weight: 0.5-2 parts of Rauwolfia, 1-5 parts of Epimedium, and 1 part of Tongkat Ali ‑5 parts, dogwood 1‑5 parts, cinnamon 1‑5 parts, leeks 1‑5 parts. The prescription of the compound Chinese medicine of the present invention comes from the proven prescription of Lin Sisong, the general manager of Xi’an Songtian Leji Biotechnology Co., Ltd., which has been passed on from generation to generation and proved to be safe and efficient by folk volunteers for more than 30 years. Leehom, this prescription mainly uses epimedium, dogwood, etc. to nourish the liver and kidney, and is the foundation of treating weak kidney yang, supplemented by extracts of Rauwolfia, Tongkat Ali, etc. The seed extract is a medicine for invigorating the kidney and yang, treating blood stasis and unfavorable symptoms of bladder gasification; the whole prescription is based on syndrome differentiation and treatment, and the overall conditioning can achieve the effect of treating both symptoms and root causes, and can effectively treat benign prostatic hyperplasia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a compound traditional Chinese medicine and its application in treating benign prostatic hyperplasia. Background technique [0002] Benign prostatic hyperplasia (BPH), often called benign prostatic hyperplasia (BPH), is the most common disease causing voiding disorders in middle-aged and elderly men, and it is also one of the most common diseases in urology. With the aging of the global population, the incidence of benign prostatic hyperplasia increases with age, but when there are hyperplasia lesions, there may not be clinical symptoms. Most patients will have increased symptoms such as dysuria with age; the incidence rate in urban areas is higher than that in rural areas, and Ethnic differences also affect the degree of hyperplasia. The main manifestations are histological hyperplasia of prostatic stroma and glandular components, anatomical prostatic enl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8962A61P13/08
CPCA61K36/185A61K36/24A61K36/296A61K36/40A61K36/54A61K36/8962A61K2236/37A61P13/08A61K2300/00
Inventor 林嗣松王四旺
Owner 林嗣松
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