A traditional Chinese medicine composition for treating women's climacteric syndrome and its preparation method

Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating women's climacteric syndrome, its preparation method and its application in treating climacteric syndrome. The raw material medicine composition of the composition is Cimicifuga: puerariae: red peony: roasted licorice at a ratio of 1:1 to 1.5:1:1. The preparation method of the extract of the composition is a conventional water decoction and alcohol precipitation process, or ethanol immersion, reflux, filtration to remove residue, filtrate to stand still, further filtration to remove residue, recovery of ethanol, drying and crushing to obtain the product. The extract of the composition contains effective active ingredients such as acteoside, isoferulic acid, puerarin, paeoniflorin, glycyrrhizic acid, glycyrrhetinic acid, liquiritin and the like. The extract obtained from the traditional Chinese medicine composition of the present invention has a significant therapeutic effect on the climacteric syndrome model caused by castrated female rats, can significantly increase the uterine wet weight and uterine coefficient of the model rats, and inhibit the abnormal increase in the body temperature of the model rats. High, and have obvious recovery and regulation effects on estrogen levels such as E2, FSH, LH.

Description

technical field

[0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating women's climacteric syndrome, its preparation method and its application in treating climacteric syndrome. Background technique

[0002] Menopausal syndrome, also known as perimenopausal syndrome, refers to a period of time before and after menopause in women, due to a sharp drop in estrogen levels, resulting in imbalance of the hypothalamus-pituitary-gonadal axis, and the occurrence of autonomic dysfunction or disorder. The main symptoms, about 25% of menopausal women have serious symptoms, because the estrogen level drops suddenly, causing a series of symptoms such as vaginal and / or uterine atrophy and dryness, osteoporosis, dizziness, headache, heat and sweating. This disease belongs to the categories of TCM "diseases before and after menopause", "dryness of the viscera" and "stagnation syndrome". Before and a...

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