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Application of composition in preparing health care product for improving sexual function or oligospermia and asthenospermia

A technology for improving sexual function and composition, applied in the direction of application, drug combination, medical preparations containing active ingredients, etc., can solve problems such as low fertility, improve sexual function, increase sperm motility and quantity, and shorten the latency period of erection Effect

Inactive Publication Date: 2019-05-31
BY HEALTH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In asthenospermia, the sperm is unable to move forward, and it is difficult to pass through the cervical canal, uterine cavity, and directly reach the fallopian tube to combine with the egg, resulting in low fertility

Method used

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  • Application of composition in preparing health care product for improving sexual function or oligospermia and asthenospermia
  • Application of composition in preparing health care product for improving sexual function or oligospermia and asthenospermia
  • Application of composition in preparing health care product for improving sexual function or oligospermia and asthenospermia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1: Improve sexual function, improve sperm motility

[0021] 1. Test method: After SD rats were raised to 8 weeks old, they were randomly divided into blank group, model group, positive control group, first control group, second control group, third control group, and test group according to body weight. Divided into 20 / group, half male and half male. Unilateral orchidectomy was performed on the male mice. On the day after the penicillin injection, the male mice were given the corresponding test substance solution by intragastric administration in two batches, with a volume of 10 mL / kg body weight, once per day, for 35 consecutive days. The female mice underwent ovariectomy, and 2 days before the mating test, the female mice were subcutaneously injected with estradiol benzoate injection, 1 mL / kg body weight. Four hours before the mating test, female mice were injected with progesterone injection, 1 mL / kg body weight. On the 30th day after the test sample w...

Embodiment 2

[0047] Example 2: Effect on oligoasthenospermia, improving sperm count and motility

[0048] 1. Test method: 105 SPF grade ICR male mice were randomly divided into normal control group, model group, positive control group, first control group, second control group, third control group, The experimental group consisted of 15 mice, among which 90 mice were given intraperitoneal injection of cyclophosphamide 2.0 mg / kg, once a day, for 5 consecutive days to establish a mouse model of oligospermia and asthenospermia. Another 15 mice were intraperitoneally injected with 0.9% sodium chloride injection (20.0 mL / kg) as the normal control group. After modeling, 5 animals in each group were collected to collect semen for sperm analysis. If the sperm density, sperm motility and sperm activity of the modeled mice were significantly lower than those of the normal control group, and the sperm deformity rate was significantly higher than that of the normal control group mice, it indicates th...

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Abstract

The invention discloses application of a composition in preparting a health care product for improving the sexual function or oligospermia and asthenospermia. The composition comprises herba epimediiextracts, American ginseng extracts and fructus tribuli extracts. Through pharmacological research, it is found that the herba epimedii extracts, the American ginseng extracts and the fructus tribuliextracts are compounded, synergistic interaction between all the components is achieved, the capture number and the ejaculation number can be increased, the erection incubation period is shortened, the effect of improving the sexual function is achieved, the effects of improving the sperm motility and increasing the amount of sperms are achieved, and the composition has a good effect on improvement of the oligospermia and asthenospermia.

Description

technical field [0001] The invention relates to the technical field of health products, in particular to the application of a composition in the preparation of health products for improving sexual function or oligospermia. Background technique [0002] Oligospermia is a condition in which the number of sperm in semen is lower than that of a normal fertile man. That is to say, the World Health Organization stipulates that the sperm count of men should not be less than 20 million per milliliter, and if it is less than 20 million, it will be called oligospermia. The high incidence of male infertility caused by the decrease in sperm count is one of the important reasons for male infertility. The causes of oligospermia include reproductive tract infection, immune factors, varicocele, endocrine abnormalities, abnormal seminal plasma, environmental factors, systemic diseases, iatrogenic and congenital factors such as cryptorchidism and immobile ciliary syndrome, and idiopathic ol...

Claims

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Application Information

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IPC IPC(8): A61K36/296A61P15/08A23L33/105A23P10/30
Inventor 汪玉芳张铭辉张旭光贺瑞坤陈洁华杨明喆
Owner BY HEALTH CO LTD
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