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Blood-nourishing Chinese angelica capsule and method for preparing same

A technology of blood angelica and capsules, which is applied in the field of medicine, can solve the problems of insignificant curative effect, weakening, waste of medicinal materials and overall medicinal efficacy, etc., and achieve the effects of avoiding waste of medicinal materials, improving symptoms, and improving blood rheology indicators.

Active Publication Date: 2019-06-14
四川乐嘉药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Yangxue Danggui Capsules originated from the classic traditional Chinese medicine "Bazhen Decoction", which is formulated from Astragalus, Angelica, Radix Paeoniae Alba, Codonopsis pilosula, Poria cocos, Rehmannia glutinosa, Zhilicorice and Chuanqiong. It is currently a commonly used traditional Chinese medicine for the treatment of primary dysmenorrhea, but currently Yangxue Danggui Capsules are mainly effective for patients with mild or moderate primary dysmenorrhea. For severe patients, the curative effect is not obvious, and painkillers are still needed to continue working
[0004] In addition, the main ingredient in Yangxue Angelica Capsules is Angelica sinensis, and the existing preparation method usually extracts Angelica sinensis with alcohol to obtain its alcohol-soluble component ferulic acid. This method loses other important water-soluble active ingredients in Angelica sinensis, For example, Angelica polysaccharides, which are contrary to the concept of combining the ingredients of traditional Chinese medicine to exert their medicinal effects, which may lead to the waste of medicinal materials and the weakening of the overall medicinal effect

Method used

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  • Blood-nourishing Chinese angelica capsule and method for preparing same
  • Blood-nourishing Chinese angelica capsule and method for preparing same
  • Blood-nourishing Chinese angelica capsule and method for preparing same

Examples

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Comparison scheme
Effect test

Embodiment 1

[0051] Prepare Yangxue Angelica Capsules according to the following prescription and method.

[0052] Formula: Weigh the medicinal materials according to the following parts by weight: 888 parts of angelica, 58 parts of white peony root, 58 parts of Rehmannia glutinosa, 58 parts of Poria cocos, 58 parts of Atractylodes macrocephala, 58 parts of Codonopsis pilosula, 58 parts of astragalus, 26 parts of Chuanxiong, 26 parts of Caulis Spatholobus, 14 parts of ginger, 3 parts of honey.

[0053] Preparation:

[0054] (1) Except honey, each raw material is crushed for later use (among them, angelica is crushed to 180-250 μm);

[0055] (2) Add 70% ethanol of 10 times the weight of mixed powder to Angelica sinensis, Chuanqiong and Caulis Spatholobus, reflux and extract twice, each time for 2.5 hours, combine alcohol extracts, filter and concentrate into a thick paste;

[0056] (3) Mix Codonopsis pilosula, Rehmannia glutinosa, Astragalus membranaceus, and ginger, add water 15 times th...

Embodiment 2

[0059] Prepare Yangxue Angelica Capsules according to the following prescription and method.

[0060] Formula: Weigh the medicinal materials according to the following parts by weight: 886 parts of angelica, 53 parts of white peony root, 53 parts of Rehmannia glutinosa, 53 parts of Poria cocos, 53 parts of Atractylodes macrocephala, 53 parts of Codonopsis pilosula, 53 parts of astragalus, 27 parts of Chuanxiong, 27 parts of Caulis Spatholobus, 13 parts of ginger and 2 parts of honey.

[0061] Preparation method: capsules were prepared according to the method described in Example 1, the difference being that Angelica sinensis was crushed to 100-150 μm.

Embodiment 3

[0063] Prepare Yangxue Angelica Capsules according to the following prescription and method.

[0064] Formula: Weigh the medicinal materials according to the following parts by weight: 886 parts of Angelica, 55 parts of Radix Paeoniae Alba, 55 parts of Rehmannia glutinosa, 55 parts of Poria cocos, 55 parts of Atractylodes macrocephala, 55 parts of Codonopsis pilosula, 55 parts of Astragalus, 28 parts of Chuanxiong, 28 parts of Caulis Spatholobus, 12 parts of ginger and 2.5 parts of honey.

[0065] Preparation:

[0066] (1) Except for ginger and honey, all raw materials are crushed for later use (angelica is crushed to 100-150 μm);

[0067] (2) Angelica sinensis was soaked in 80°C water at a constant temperature for 1 hour. The amount of water used was 12 times the weight of Angelica sinensis, and then extracted 3 times in 80°C microwave (300W), 10 minutes each time, filtered, and the filter residue was used for later use, and the filtrate was combined for later use;

[0068]...

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Abstract

The invention discloses a blood-nourishing Chinese angelica capsule and a method for preparing the same. The blood-nourishing Chinese angelica capsule is prepared from, by weight parts, 880-900 partsof Chinese angelica, 50-60 parts of white peony root, 50-60 parts of prepared rehmannia root, 50-60 parts of poria cocos, 50-60 parts of rhizoma atractylodis, 50-60 parts of radix codcnopsitis pilosulas, 50-60 parts of radix astragali, 25-30 parts of rhizoma chuanxiong, 25-30 parts of suberect spatholobus stem, 10-15 parts of fresh ginger and 2-3 parts of honey. By adding or reducing herbal medicines a conventional famous formula 'bazhen decoction', the treatment effect on patients with primary dysmenorrhea, especially on moderate to severe patients, is enhanced, and the blood-nourishing Chinese angelica capsule invigorates qi, promotes the circulation of qi, enriches the blood and invigorates the circulation of blood, the compatibility is scientific and reasonable, and the curative effectis exact.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a blood-nourishing angelica capsule and a preparation method thereof. Background technique [0002] Primary dysmenorrhea is functional dysmenorrhea, which refers to menstrual pain, often spasmodic, concentrated in the lower abdomen. Other symptoms include headache, fatigue, dizziness, nausea and vomiting, diarrhea, and low back and leg pain, which are very common symptoms among young women. In severe cases, they need to stay in bed for several hours or days, which greatly affects daily life. Primary dysmenorrhea is not associated with obvious organic pelvic disease. Primary dysmenorrhea belongs to the category of "abdominal pain during menstruation" in the theory of traditional Chinese medicine, which is mostly caused by insufficient kidney qi, insufficient qi and blood, cold palace and blood stasis, and emotional imbalance. [0003] Yangxue Danggui Capsules origin...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/48A61K47/46A61P15/00A61K35/644
Inventor 吴春丁锋母绍东邓春燕
Owner 四川乐嘉药业有限公司
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