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31results about How to "Obvious symptoms" patented technology

Chinese medicine for treating apoplexy hemiplegia sequela

The invention discloses a Chinese herbal medicine in the treatment of sequels of stroke and hemiplegia. The active pharmaceutical ingredient and weight ratios are demonstrated as follows: ground beetle 3-10g, astragalus 9-40g, codonopsis pilosula extract 10-30g, leonurus japonicus 9-30g, danshen root 9-15g, cyathula root 5-10g, peach kernel 5-10g, Jiang Chong 10-20g, safflower 5-9g, rhizoma ligustici wallichii 5-15g, scorpion 3-9g, lumbricus 5-10g, red peony root 6-12g, poria cocos 5-15g, chinese starjasmine stem 6-12g, stephania root 5-15g, coix seed 9-30g, crab apple 9-12g, eucommia bark 6-15g, combined spicebush root 5-10g, largehead atractylodes rhizome 6-15g, oriental waterplantain rhizome 6-15g, milettia reticulata 10-20g, gambir plant 5-12g, angelica sinensis 5-15g, turmeric rhizome 5-9g, cassia twig 3-9g, mulberry twig 10-20g, chinese clematis root 6-10g. That the sequels of stroke and hemiplegia are difficult to cure is because that muscle and joints are blocked by phlegm and blood stasis, which is caused by the deficiency of Qi. The prescription based on the pathogenesis, by righting and supporting the healthy energy, activating blood circulation to dissipate blood stasis, reducing phlegm and adjusting the balance of Yin and Yang, removes the causes of the illness and the total efficiency for the prescription is more than 98%.
Owner:向祚伟

Nimodipine pulse sustained release mircopill preparation and preparing method thereof

The invention relates to a pulsed sustained-release pellet comprising nimodipine and a preparation method is also provided. The sustained-release pellet comprises: one of gastric-dissolved and medicines containing sustained-release pellets and enteric-coated and medicines containing sustained-release pellets, or the combination. The preparation method is that: making medicines containing pellets using nimodipine and excipents, coating the medicines containing pellets with the gastric coating or the enteric coating, mixing the sustained-release pellets coated with gastric coating and enteric coating in proportion and putting the sustained-release pellets into capsules or tabletting. The pulsed sustained-release pellet of the invention has a special release behavior and needs to be taken only once per day. The release curve agrees well with the disease circadian rhythm of cerebrovascular disease patients, playing a role of the best prevention and treatment.
Owner:SHENZHEN SOUTH CHINA PHARMA

Ketamine-induced schizophrenia animal model and mechanism study

The present invention provides a ketamine-induced schizophrenia animal model and mechanism study. The study includes the following steps: 1) ketamine-induced schizophrenia animal model establishment;2) behavioral and morphological observation after ketamine-induced schizophrenia; 3) correlation with oxidative stress after ketamine-induced schizophrenia. Systemic observations are carried out on schizophrenia-like symptoms caused by single- or continuous-dose administration of small, medium, and large doses of ketamine to mice, the feasibility of establishing models of different doses and different administration ways is subjected to comparison and preliminary evaluation, and results show that single- or continuous-dose administration of ketamine can induce symptoms similar to schizophreniain mice and lead to a dose-dependent trend to a certain extent. In addition, through analysis, oxidative stress is correlative after ketamine-induced symptoms similar to schizophrenia of mice are developed, and a basis for study on subsequent ketamine addiction mechanism and schizophrenia is provided.
Owner:KUNMING MEDICAL UNIVERSITY

Method for quickly identifying disease resistance of inoculated in vitro branched to pear fire blight

The invention relates to the technical field of plant protection, and particularly discloses a method for quickly identifying disease resistance of inoculated in vitro branched to pear fire blight. The method comprises the following steps of (1) preparing erwinia amylovora inoculating liquid; (2) preparing in vitro branches; (3) performing inoculation; and (4) evaluating variety disease resistance. According to the identifying and evaluating method for the disease resistance of the pear fire blight, provided by the invention, pathogenesis symptoms and pathogeny quantifying through a molecularbiology technique are combined, so that the method is quick, simple, standard and practical, the result is accurate and reliable, and the method is suitable for performing quick identification and screening on disease resistance of bulk materials.
Owner:XINJIANG AGRI UNIV

Rhinitis patch

The invention discloses a rhinitis patch for curing chronic rhinitis and sinusitis, which is prepared by traditional Chinese medicine honeylocust fruit, asarum, flos magnoliae, dahurian angelica, rhizomaligusticiwallichii, rotofpeony, acorus gramineus, olibanum, commiphora molmol, resina draconis, menthol, matrix tender honey, maltose, colophony and preservative ethylparaben. The prepared rhinitispatch plaster can realize the purposes of restoring olfactory function and curing chronic rhinitis and sinusitis only by outer coating on acupoints.
Owner:合肥新中医学研究中心

Medicine for reducing clinical side effects of metaproterenol aerosol

The invention discloses a medicine for reducing the clinical side effect of probuterol aerosol, which belongs to the technical field of medicines. The aerosol is made of probutene, biological agent, tetrafluoroethane, absolute ethanol, spar, sodium dodecylsulfonate and apple flavor according to certain parts by weight. Clinical trials have proved that the drug effectively overcomes the problem of side effects in the treatment of chronic bronchitis with the commercially available probuterol aerosol.
Owner:沂南县众友中药材种植专业合作社

Medicine composition contg. Tamsulosin and calcium antagonist

A composite medicine for treating hypertension and the diseases associated with prostatoplasia contains Tansuoluoxin or its active metabolite or its precursor or its addition salt, antagon or its metabolite or its salt, and medicinal carrier or excipient.
Owner:BEIJING HUAANFO BIOMEDICAL RES CENT

Novel plaster for treating lumbar and cervical vertebra diseases and rheumatism

The invention discloses a novel plaster for treating lumbar and cervical vertebra diseases and rheumatism.The novel plaster is mainly prepared from 58 kinds of Chinese herbal medicines including radix notoginseng, dragon blood, frankincense, flos carthami, the rhizome of chuanxiong, rhizoma drynariae, rhizoma homalonemae, fineleaf schizonepeta herb, garden balsam stem, radix sileris, myrrh, radix angelica sinensis, rhizoma cibotii, radix angelicae pubescentis, radix aconiti agrestis and common clubmoss herb.The 58 kinds of Chinese herbal medicines are placed in a purple pottery boiler to be soaked for 30 h in pure sesame oil and then fried for 12 min with raging fire and then with slow fire for 36 min in an iron pan, stirring is conducted with a stick constantly, medicinal materials in the pan are taken out after frying, and the rest is poured into a steel cylinder and cooled for over 24 h to generate the plaster.People can heat the steel cylinder and scoop out the material with a wood spoon when the plaster is needed, and 15-17 g material is spread onto a cotton cloth or non-woven fabric which is 15 cm long and 13 cm wide, so that a finished plaster product is obtained.
Owner:段长岭

Pyroxasulfone-containing synergistic weeding composition, and application thereof in control of wheat field weeds

The invention relates to a pyroxasulfone-containing synergistic weeding composition, and an application thereof in control of wheat field weeds, belongs to the technical field of pesticides, and discloses a weeding composition being safe to wheat and having a significant control effect on malignant weeds and resistant weeds in the wheat field. The effective components of the weeding composition are pyroxasulfone and florasulam, and a weight part ratio of the pyroxasulfone to the florasulam in the composition is (9-99):1, and preferably (19-59):1. Different auxiliary materials can be added to the composition in order to prepare missible oil, a suspoemulsion, a suspension, a wettable pulvis or a water dispersible granule. The weeding composition has obvious synergistic effects, can realize application of the composition to weeds, has a long persistent period, can effectively control wheat field weeds emerging in different stages, including various resistant weeds, such as Sclerochloa kengiana, Lolium multiflorum Lamk., resistant flixweed and resistant bedstraw, has a higher activity than existing most wheat herbicides, and is an efficient and safe wheat field weeding composition.
Owner:JINAN KESAI AGROCHEM

Traditional Chinese medicine for treating gastric cancer, and preparation method thereof

The invention discloses a traditional Chinese medicine for treating gastric cancer. The traditional Chinese medicine is prepared by using the following raw medicines, by weight, 12-30 parts of Radix Curcumae Aromaticae, 15-40 parts of Pinellia Tuber, 5-20 parts of Artemisia capillaries, 2-10 parts of sliced ginger, 3-15 parts of rhizoma gastrodiae, 5-20 parts of unprepared Atractylis lancea, 10-20 parts of Cordyceps sinensis, 3-15 parts of Lithospermum erythrorhizon, 4-10 parts of Isatis Root, 5-20 parts of radix bupleuri, 11-25 parts of Camomile, 12-25 parts of honeysuckle flower, 13-27 parts of Trichosanthis Radix, 1-3 parts of Lophatherum gracile, 2-6 parts of Wrinkled Gianthyssop, 2-10 parts of Radix Puerariae, 2-10 parts of hawthorn fruit, 2-10 parts of periostracum cicadae, 6-8 parts of Akebia Stem, 3-7 parts of soybean, 8-10 parts of betel nut, 4-6 parts of Phytolacca acinosa Roxb, 4-8 parts of Gentiana macrophylla, 3-6 parts of Chinese prickly ash, 6-12 parts of Musa sapientum L., 3-8 parts of Sophora flavescens and 5-20 parts of millet sprout.
Owner:孙志芳

Blood-nourishing Chinese angelica capsule and method for preparing same

The invention discloses a blood-nourishing Chinese angelica capsule and a method for preparing the same. The blood-nourishing Chinese angelica capsule is prepared from, by weight parts, 880-900 partsof Chinese angelica, 50-60 parts of white peony root, 50-60 parts of prepared rehmannia root, 50-60 parts of poria cocos, 50-60 parts of rhizoma atractylodis, 50-60 parts of radix codcnopsitis pilosulas, 50-60 parts of radix astragali, 25-30 parts of rhizoma chuanxiong, 25-30 parts of suberect spatholobus stem, 10-15 parts of fresh ginger and 2-3 parts of honey. By adding or reducing herbal medicines a conventional famous formula 'bazhen decoction', the treatment effect on patients with primary dysmenorrhea, especially on moderate to severe patients, is enhanced, and the blood-nourishing Chinese angelica capsule invigorates qi, promotes the circulation of qi, enriches the blood and invigorates the circulation of blood, the compatibility is scientific and reasonable, and the curative effectis exact.
Owner:四川乐嘉药业有限公司

Artificial inoculation method of Athetis lepigone

The invention belongs to the field of pesticide bioassay and particularly discloses an artificial inoculation method of Athetis lepigone. The artificial inoculation method comprises the steps of spreading a poison bait of a pesticide or granules to be detected on to-be-detected pesticide-coated corn seeds or basal parts of corn seedling stems; and inoculating 3-5-aged Athetis lepigone larvae on corn seedlings in the 2-3 leaf periods, placing an inoculation medium on the basal parts of the corn seedling stems, covering by using a protective cover, placing the larvae on the inoculation medium, and surveying. The invention provides an accurate and reliable method for screening a pesticide for preventing or controlling Athetis lepigone; secondarily, the selected three-year-old larvae are high in pesticide sensitivity, appetite, action capacity and corn seedling feeding rate; in addition, due to the arrangement of the inoculation medium and the protective cover in the method, the escape rate of the larvae is low, and the larvae are prevented from being eaten by natural enemies; and the basal parts of the corn seedling stems in the 2-3 leaf periods in the method are tender in tissue and are more suitable for being eaten by the larvae, and the symptoms are remarkable after the basal parts of the corn seedling stems are eaten.
Owner:INST OF PLANT PROTECTION HEBEI ACAD OF AGRI & FORESTRY SCI

Process for detecting concentration of nonionic surfactant in waste water using spirogyra

This invention relates to a method to test the non-ion surface activity agent concentration in the waste water by use of water sponge, which comprises the following steps: using spirogyra sponge as target object; diluting the non-ion surface activity agent standard sample and adding the water sponge in growth and observing the water sponge cell structure changes under microscope to find out the threshold concentration; diluting the sample and adding small quantity of water sponge and observing the water sponge cell damage situations by microscopes; getting the non-ion surface activity agent concentration by the formula depicted.
Owner:HUNAN UNIV

Method for detecting anionic surfactant concentration in waste water using spirogyra

Spirogyra as a fresh water green alga is used as cell structural form changing target in detecting the anionic surfactant concentration in water solution. Standard sample of anionic surfactant is diluted to compound serial diluted samples with gradient concentrations; and the samples are added with Spirogyra and observed in microscope to find out the critical concentration for Spirogyra cell structure to change. The sample to be detected is diluted, added with small amount of Spirogyra and observed in microscope to find out the maximum dilution multiple without damage to Spirogyra. The anionic surfactant concentration is calculated based on the formula of anionic surfactant concentration= critical concentration x maximum dilution multiple. The method is fast, simple and practical.
Owner:HUNAN UNIV

MiR-81 as well as mimics and application thereof

The invention discloses miR-81 as well as mimics and application thereof, and belongs to the field of disease gene therapy. The invention provides miR-81 with a nucleotide sequence as shown in SEQ ID NO.1, the miR-81 is used as a novel miRNA, and a mimic of the miR-81 has a certain prevention and / or treatment effect on gouty arthritis, so that a novel target is provided for drug treatment of the gouty arthritis. The miR-81 simulant is a small-fragment single-chain RNA (Ribonucleic Acid) designed and synthesized aiming at the nucleotide sequence of the miR-81, and the sequence of the small-fragment single-chain RNA is reversely complementary with the nucleotide sequence of the miR-81. The miR-81 simulant can reduce the inflammatory response of gouty arthritis by reducing the expression level of interleukin-1 beta protein and TNF-alpha, so that joint swelling is relieved, and the miR-81 simulant has huge application potential in the aspects of prevention and treatment of gouty arthritis.
Owner:GUANGZHOU UNIVERSITY OF CHINESE MEDICINE

MiR-75 as well as mimics and application thereof

The invention discloses miR-75 as well as mimics and application thereof, and belongs to the field of disease gene therapy. The invention provides miR-75 with a nucleotide sequence as shown in SEQ ID NO.1. The miR-75 is used as a novel miRNA, and a mimic of the miR-75 has a certain prevention effect on gouty arthritis, so that a novel target is provided for drug treatment of the gouty arthritis. The miR-75 simulant is a small-fragment single-chain RNA (Ribonucleic Acid) designed and synthesized aiming at the nucleotide sequence of the miR-75, and the sequence of the small-fragment single-chain RNA is reversely complementary with the nucleotide sequence of the miR-75. The miR-75 simulant can reduce the inflammatory response of gouty arthritis by reducing the expression level of interleukin-1 beta protein, so that joint swelling is relieved, and the miR-75 simulant has huge application potential in the aspects of prevention and treatment of gouty arthritis.
Owner:GUANGZHOU UNIVERSITY OF CHINESE MEDICINE

A kind of sleeve for dacryocystorhinostomy and preparation method thereof

The invention discloses a cannula used for dacryocystorhinostomy and a preparation method thereof. The cannula includes a drainage pipe, an oval drainage disc and a tail fixing screw are arranged at both ends of the drainage pipe respectively, the drainage pipe is in a hollow shape, a conduction channel is formed in the drainage pipe, a canula body is arranged at the tail end of the drainage pipe,and the cannula body is fixed to the tail fixing screw at a hole forming place in a nasal cavity through a buckle. A hollow silica gel catheter is selected and penetrated to serve as the drainage pipe, and the two ends of the drainage pipe are both polished for assembly of components; according to shape requirements, heating for shaping is conducted on the drainage pipe, and the drainage pipe iscooled naturally after thermoplastic shaping and disinfected for use. More convenience is provided for implanting, the drainage pipe only needs to be implanted from a lower lacrimal punctum and then can reach the hole forming place, extra traction devices are not required, only few minutes are consumed, and complicated treatment such as knotting is not required in the nasal cavity, so that patients feel comfortable, and no secondary injuries are caused; by designing the drainage pipe in a hollow shape, tears can be drained normally, infection is not caused easily, and symptoms are alleviated obviously during implanting.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

A superimposed sleeve for dacryocystorhinostomy and preparation method thereof

The invention discloses a folded cannula used for dacryocystorhinostomy and a preparation method thereof. The folded cannula includes a drainage header pipe and a drainage branch pipe, and a bubble bag is arranged on the drainage header pipe; an oval drainage disc and a tail fixing screw are arranged at both ends of the drainage branch pipe respectively, the tail fixing screw extends to an internal hole forming part of a nasal cavity, and a cannula body used for fixation is installed on the tail fixing screw through a buckle. A hollow silica gel catheter is selected, after the two ends of thesilica gel catheter are penetrated, the silica gel catheter is adopted as the drainage header pipe, and the drainage branch pipe is fixedly installed along the central axes of the two ends of the drainage header pipe; the end faces of the outer side of the drainage branch pipe are all polished, and the oval drainage disc and the tail fixing screw are additionally arranged; according to shape requirements, heating for shaping is conducted on the drainage pipes. More convenience is provided for implanting, extra traction devices are not required, complicated treatment such as knotting is not required in the nasal cavity, patients feel comfortable, and no secondary injuries are caused; by designing the drainage pipes in hollow shapes, tears can be drained normally, infection is not caused easily, and symptoms are alleviated obviously during implanting.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Chinese medicine for treating apoplexy hemiplegia sequela

The invention discloses a Chinese herbal medicine in the treatment of sequels of stroke and hemiplegia. The active pharmaceutical ingredient and weight ratios are demonstrated as follows: ground beetle 3-10g, astragalus 9-40g, codonopsis pilosula extract 10-30g, leonurus japonicus 9-30g, danshen root 9-15g, cyathula root 5-10g, peach kernel 5-10g, Jiang Chong 10-20g, safflower 5-9g, rhizoma ligustici wallichii 5-15g, scorpion 3-9g, lumbricus 5-10g, red peony root 6-12g, poria cocos 5-15g, chinese starjasmine stem 6-12g, stephania root 5-15g, coix seed 9-30g, crab apple 9-12g, eucommia bark 6-15g, combined spicebush root 5-10g, largehead atractylodes rhizome 6-15g, oriental waterplantain rhizome 6-15g, milettia reticulata 10-20g, gambir plant 5-12g, angelica sinensis 5-15g, turmeric rhizome 5-9g, cassia twig 3-9g, mulberry twig 10-20g, chinese clematis root 6-10g. That the sequels of stroke and hemiplegia are difficult to cure is because that muscle and joints are blocked by phlegm andblood stasis, which is caused by the deficiency of Qi. The prescription based on the pathogenesis, by righting and supporting the healthy energy, activating blood circulation to dissipate blood stasis, reducing phlegm and adjusting the balance of Yin and Yang, removes the causes of the illness and the total efficiency for the prescription is more than 98%.
Owner:向祚伟

Hebephrenic type schizophrenia associated gene

InactiveCN106434678AThe detection effect is not goodObvious symptomsMicrobiological testing/measurementGenetic engineeringHebephrenic type schizophreniaDiagnosis methods
The invention provides an associated gene closely associated with hebephrenic type schizophrenia, namely a DRD2 gene located at 11q23; because a mononucleotide polymorphism rs1800497 base C of the gene is mutated to T, the gene is associated with susceptibility of the hebephrenic type schizophrenia, individuals with the rs1800497 base of T are a hebephrenic type schizophrenia susceptible group, and individuals with the rs1800497 base of C are a group less susceptible to the hebephrenic type schizophrenia; the DRD2 gene and an encoded protein thereof have important guiding significance on elucidating a hebephrenic type schizophrenia genetic mechanism, establishing a gene diagnosis method, and guiding hebephrenic type schizophrenia diagnosis and prevention and development of novel treatment drugs.
Owner:张建华

Weeding composition containing pyroxasulfone and quinclorac and application of weeding composition

InactiveCN109845748AExtended service lifeAvoid the problem of resistance to long-term single useBiocideAnimal repellantsBristlegrassesTriticeae
The invention discloses a weeding composition containing pyroxasulfone and quinclorac. The active ingredients of the weeding composition are pyroxasulfone and quinclorac. The weight ratio of pyroxasulfone to quincloric is (1-100):(1-100). The weeding composition can be used in maize, rice, wheat, sorghum, lawn and other crop fields and can control most annual grasses and broad-leaved weeds, including barnyard grass, eleusine indica, crabgrass, green bristlegrass, Eleocharis yokoscensis, acalypha australis, portulaca oleracea, descurainia sophia, Capsella bursa-pastoris, ammannia arenaria, Scirpus juncoides and the like which are resistant to sulfonylurea herbicides.
Owner:SHANDONG DEHAO CHEM

Emulsifiable paste for tonifying qi, reducing phlegm and relieving spasm in facial paralysis recovery phase and preparation method thereof

The invention discloses an emulsifiable paste for tonifying qi, reducing phlegm and relieving spasm in a facial paralysis recovery phase and a preparation method thereof, and solves the technical problems that the existing acupuncture therapy in the facial paralysis recovery phase is more troublesome, and the consumed time is longer. The emulsifiable paste for tonifying qi, reducing phlegm and relieving spasm in the recovery phase of facial paralysis is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 25-35 parts of astragalus membranaceus, 15-25 parts of codonopsis pilosula, 25-35 parts of raw bighead atractylodes rhizome, 10-20 parts of tribulus terrestris, 10-20 parts of radix polygoni multiflori preparata, 10-20 parts of radix paeoniae alba, 8-12 parts of angelica sinensis, 10-20 parts of rhizoma pinellinae praeparata, 10-20 parts of thunberg fritillary bulb, 1 centipede and 8-12 parts of earthworm. The emulsifiable paste has the advantages of no side effect, short treatment time and the like.
Owner:CHONGQING TRADITIONAL CHINESE MEDICINE HOSPITAL
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