205results about How to "Reduced survival" patented technology

The present invention relates generally to a method for the treatment and prophylaxis of inflammatory conditions. The present invention is predicated in part on the identification of cells of the monocyte / macrophage lineage being critical for inflammation and, in particular, chronic inflammation. In accordance with the present invention, it is proposed that the reduction in levels of monocyte / macrophage-type cells and / or a reduction in the production of inflammatory and pro-inflammatory mediators by these cells, especially locally, is effective in reducing inflammatory conditions. The present invention further provides animal models useful for screening for reducing levels of monocyte / macrophage-type cells and / or reducing the production of inflammatory and pro-inflammatory mediators of these cells.

Aquatic nuisance species (ANS) in ship's ballast water are killed by permeating to equilibrium a gaseous mixture consisting essentially of, preferably, ≧84% nitrogen, ≧11% carbon dioxide and ≦4% oxygen through ship's ballast water until the ballast water itself becomes (i) hypercapnic to ≧20 ppm carbon dioxide, and, by association, (ii) acidic to pH ≦7, while preferably further, and also, being rendered (iii) hypoxic to ≦1 ppm oxygen. The permeating is preferably realized by bubbling the gaseous mixture preferably obtained from an inert gas generator through the ballast water over the course of 2+ days while the ballast water is continually maintained a pressure less than atmosphere, preferably −2 p.s.i. or less. The (i) hypercapnic, (ii) acidic and (iii) hypoxic conditions—each of which can be independently realized—synergistically cooperate to kill a broad range of ANS in the ballast water without deleterious effect on the environment when, and if, the ballast water in which the balance of dissolved gases has been changed is discharged.

The invention provides compositions, methods, and kits for the treatment of acute myeloid leukemia in a subject.

The present invention relates to compositions comprising conjugation-competent non-dividing cells for delivery of genes to bacterial cells by conjugation. The present invention also relates to methods of making, using, and storing such conjugation competent non-dividing cells.

The invention provides a life-saving device including means for allowing the wearer to be found easily, and a body temperature adjuster for maintaining the body temperature of the wearer at a proper body temperature by fine-adjusting the body temperature of the wearer depending on the outside temperature or the body temperature until the wearer is rescued. The life-saving device includes heating members disposed so as to contact both sides of the neck where common carotid arteries run through and both armpits where axillary arteries run through when the main body of the life-saving device is worn, a power source for supplying electricity to the heating members, a body temperature detecting means for detecting the body temperature, an outside temperature detecting means for detecting the outside temperature, and a temperature controller for adjusting the temperature of the heating members in response to the temperature detected by the body temperature detecting means and the outside temperature detecting means, so that the body temperature of the wearer can be maintained at a proper temperature in case of emergency.

The invention provides compositions featuring chitosan and methods for using such compositions for the local delivery of biologically active agents to an open fracture, complex wound or other site of infection. Advantageously, the degradation and drug elution profiles of the chitosan compositions can be tailored to the needs of particular patients at the point of care (e.g., in a surgical suite, clinic, physician's office, or other clinical setting).