Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A composition for preventing and treating HIV/AIDS and its preparation method

A composition and ginseng technology, applied in the field of traditional Chinese medicine, can solve the problems of lack of scientific objective data, low investment, low starting point, etc.

Active Publication Date: 2018-04-13
BEIJING INCREASEPHARM CORP LTD
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For more than 20 years, although the advent of antiviral western medicine and the use of Hart (HARRT) therapy have effectively inhibited virus replication, significantly reduced the morbidity and mortality of opportunistic infections, and improved the quality of life of patients, many problems are far from failed to resolve
[0005] There have been more than 20 years of research on traditional Chinese medicine anti-AIDS drugs. Hundreds of traditional Chinese medicines for clearing away heat and detoxification, promoting blood circulation and removing blood stasis, tonifying and anti-tumor have been screened out, and dozens of Chinese medicine decoctions and Chinese patent medicines have achieved satisfactory clinical results, but the research on Chinese medicines is mostly preliminary laboratory research and a small number of case observations due to various reasons. Incomplete data, lack of rigorous and systematic clinical research design and objective indicators of experimental testing, lack of scientific objective data for treatment effect, and weak convincing power

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A composition for preventing and treating HIV/AIDS and its preparation method
  • A composition for preventing and treating HIV/AIDS and its preparation method
  • A composition for preventing and treating HIV/AIDS and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1）、TSZ11（ Embodiment 2

[0058] Drugs: TSZ10 (Example 1 of the present invention), TSZ11 (Example 2 of the present invention), TSZ12 (Example 3 of the present invention), 3TC (internal control), AZT (internal control)

[0059] Virus: HIV-1RF

[0060] Cell line: MT-4

[0061] Objective: To determine the anti-HIV-1 activity of the drug to be tested by cell virus experiment.

[0062] In the XTT cell virus experiment, living cells metabolize to produce XTT, so they have a high absorption value, and dead cells do not produce XTT, so the absorption value is still relatively low.

[0063] Drugs with antiviral effects protect HIV-infected cells from death caused by the virus and increase absorbance due to the production of XTT metabolites. Toxic drugs cause a large number of cells to die and produce less XTT, so the absorbance is still very low.

[0064] Preparation: Grind the drug into fine powder, dissolve it with DMSO to a concentration of 100 mg / ml, and dilute it to 10 mg / ml (10% DMSO) with medium-free...

Embodiment 1

[0114] Ginseng 129g Cordyceps 4g Angelica 148g Astragalus 148g Salvia 148g

[0115] Coix seed 148g Poria cocos 80g Rehmannia glutinosa 80g Burnt hawthorn 80g Burnt malt 80g

[0116] Jiao Shenqu 80g Licorice 80g

[0117] a) Weigh ginseng, cordyceps sinensis, angelica, astragalus, salvia miltiorrhiza, coix seed, poria cocos, rehmannia glutinosa, scorched hawthorn, scorched malt, scorched divine music, and licorice;

[0118] b) Take 50% of ginseng and the whole amount of Cordyceps sinensis and pulverize them into fine powder to obtain fine powder I for subsequent use;

[0119] c) After soaking Angelica sinensis in water for 2 hours, extract the volatile oil for 6 hours, and collect the volatile oil in another device; the extracted medicinal residue is medicinal residue I, and the medicinal liquid after oil extraction is filtered to obtain medicinal liquid I, which is set aside;

[0120] d) Salvia miltiorrhiza and coix seed plus 6 times the amount of 95% ethanol, reflux extracti...

Embodiment 2

[0124] Ginseng 80g Cordyceps 9g Angelica 100g Astragalus 200g Salvia 100g

[0125] Coix seed 200g Poria cocos 30g Rehmannia glutinosa 120g Burnt hawthorn 30g Burnt malt 120g

[0126] Jiao Shenqu 30g Licorice 120g

[0127] a) Weigh ginseng, cordyceps sinensis, angelica, astragalus, salvia miltiorrhiza, coix seed, poria cocos, rehmannia glutinosa, scorched hawthorn, scorched malt, scorched divine music, and licorice;

[0128] b) Take 50% of ginseng and the whole amount of Cordyceps sinensis and pulverize them into fine powder to obtain fine powder I for subsequent use;

[0129] c) After soaking Angelica Angelica in water for 1 hour, extract the volatile oil for 7 hours, collect the volatile oil in another device, extract the medicinal residues as medicinal residues I, and filter the medicinal liquid after extracting the oil to obtain medicinal liquid I for later use;

[0130] d) Salvia miltiorrhiza and coix seed plus 4 times the amount of 80% ethanol to reflux extract 4 times, 0...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a composition for preventing and treating HIV / AIDS and a preparation method thereof. The pharmaceutical composition is prepared from ginseng, cordyceps sinensis, angelica, astragalus, salvia miltiorrhiza, coix seed, poria cocos, rehmannia glutinosa, hawthorn, malt, divine comedy and licorice according to a certain weight ratio. The composition has the effects of nourishing qi and blood, invigorating the spleen and benefiting the lungs, and can be used to treat AIDS and HIV-infected patients with deficiency of qi and blood, such as mental fatigue, shortness of breath, lazy speech, anorexia, spontaneous sweating, and easy cold; dizziness Dizziness, palpitations, insomnia, numbness of hands and feet, etc. It is prepared as any oral formulation, preferably tablet.

Description

technical field [0001] The invention relates to a composition for preventing and treating HIV / AIDS and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] AIDS (AIDS), also known as acquired immunodeficiency syndrome, is caused by human immunodeficiency virus (HIV) infection. With the rapid spread of HIV around the world, people are facing the serious threat of AIDS. The rate is so high that it is called "super cancer". For more than 20 years, although the advent of antiviral western medicine and the use of Hart (HARRT) therapy have effectively inhibited virus replication, significantly reduced the morbidity and mortality of opportunistic infections, and improved the quality of life of patients, many problems are far from failed to resolve. [0003] Since the first AIDS patient was discovered in the United States in 1981, about 70 million people have been found to be infected with HIV around the worl...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61P31/18
Inventor 田圣勋张宏
Owner BEIJING INCREASEPHARM CORP LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com