Temperature gradient control method in distillation process of pharmaceutical intermediates

Abstract

The invention discloses a temperature gradient control method in distillation process of pharmaceutical intermediates. The fully automatic gradient control of temperature can be realized through the linkage of a temperature control valve and a temperature master controller. The advantages of the method are as follows: 1, the accurate and timely control during distillation can be realized through the linkage of a temperature controller, a temperature monitor and the temperature control valve, so that the occurrence of overtemperature and overpressure phenomenon can be completely eradicated, andthe operation safety during the distillation can be fully guaranteed; and 2, the fully automatic control of temperature can be realized, so that manpower resources can be saved.

Description

technical field [0001] The invention relates to the field of distillation technology, in particular to a temperature gradient control method in the distillation technology of pharmaceutical intermediates. Background technique [0002] During the distillation process of a pharmaceutical intermediate, it is necessary to heat up and cool down the distillation pot according to the distillation requirements. The traditional temperature control method is to link the temperature inside the still pot with the steam regulating valve and the cooling water regulating valve respectively, and the temperature rises, cools down and During the heat preservation, the distillation process is completed under the control of the operator. In the traditional temperature control operation, human factors dominate, and overtemperature and overpressure are prone to occur. Operational accidents are prone to occur when overtemperature and overpressure occur, resulting in equipment punching and even exp...

AI Technical Summary

Problems solved by technology

In the traditional temperature control operation, human factors dominate, and overtemperature and overpressure are prone to occur. Operational accidents are prone to occur when overtemperature and overpressure occur, resulting in equipment punching and even explosion, which poses a great safety hazard. And need to be equipped with special care, resulting in a waste of human resources

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