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A traditional Chinese medicine compound composition for treating ovulation disorder infertility and its application

A technology for infertility and composition, which is applied in the field of traditional Chinese medicine compound composition, and achieves the effect of high cycle ovulation rate, good treatment effect and little influence

Active Publication Date: 2021-08-24
苏州市吴江区中医医院(苏州市吴江区第二人民医院)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, due to long-term anovulation and excessive endometrial hyperplasia without the antagonistic effect of cyclic progesterone, there is still a high risk of developing endometrial cancer or breast cancer.

Method used

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  • A traditional Chinese medicine compound composition for treating ovulation disorder infertility and its application
  • A traditional Chinese medicine compound composition for treating ovulation disorder infertility and its application
  • A traditional Chinese medicine compound composition for treating ovulation disorder infertility and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation method (tablet) of embodiment 1 Chinese medicine compound composition

[0025] 1. A Chinese medicine compound composition for treating ovulatory infertility, which is made of the following raw materials in parts by weight:

[0026]

[0027] 2. A method for preparing a compound Chinese medicine composition for treating ovulatory infertility, comprising the following steps:

[0028] (1) Take each raw medicinal material according to the parts by weight of the above 1 and put it in a multifunctional extraction tank, add 10 times the amount of the total medicinal materials and soak for 0.5 hour; then decoct and extract for 1.5 hour, filter, and take the filtrate for subsequent use;

[0029] (2) Take the medicinal residues and add 6 times the amount of water to the total medicinal materials again, decoct for 1.5 hours, filter, and take the filtrate for subsequent use;

[0030] (3) Merge the two filtrates, concentrate under reduced pressure, and dry in vacu...

Embodiment 2

[0032] The preparation method (capsule) of embodiment 2 Chinese medicine compound composition

[0033] 1. A Chinese medicine compound composition for treating ovulatory infertility, which is made of the following raw materials in parts by weight:

[0034]

[0035] 2. A method for preparing a compound Chinese medicine composition for treating ovulatory infertility, comprising the following steps:

[0036] (1) Take each raw medicinal material according to the parts by weight of the above 1 and put it in a multifunctional extraction tank, add 8 times the amount of total medicinal materials and soak for 1 hour; then decoct and extract for 1 hour, filter, and take the filtrate for subsequent use;

[0037] (2) Take the filter residue and add water of 8 times the amount of the total medicinal materials again, decoct for 1 hour, filter, and take the filtrate for subsequent use;

[0038] (3) Merge the two filtrates, concentrate under reduced pressure, and dry in vacuo to obtain the...

Embodiment 3

[0040] The preparation method (granule) of embodiment 3 Chinese medicine compound composition

[0041] 1. A Chinese medicine compound composition for treating ovulatory infertility, which is made of the following raw materials in parts by weight:

[0042]

[0043] 2. A method for preparing a compound Chinese medicine composition for treating ovulatory infertility, comprising the following steps:

[0044] (1) Take each raw medicinal material according to the parts by weight of the above 1 and put it in a multifunctional extraction tank, add 12 times the amount of the total medicinal materials and soak for 1.5 hours; then decoct and extract for 2 hours, filter, and take the filtrate for subsequent use;

[0045] (2) Take the filter residue of step (1) and add water of 8 times the amount of the total medicinal materials again, decoct for 1.5 hours, filter, and take the filtrate for subsequent use;

[0046] (3) Merge the two filtrates, concentrate under reduced pressure, and dry ...

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Abstract

The invention discloses a traditional Chinese medicine compound composition for treating ovulatory infertility and its application. ~6 parts, 1~6 parts of salvia miltiorrhiza, 1~9 parts of raspberry, 1~6 parts of Chinese yam, 1~9 parts of northern sand ginseng, 1~6 parts of dodder seed, 1~7.5 parts of golden cherry seed and 1~6 parts of jujube seed portion made. The traditional Chinese medicine compound composition provided by the invention is applied to the clinical treatment of ovulation disorder infertility under the guidance of the theory of traditional Chinese medicine, and a good therapeutic effect has been achieved. The results of clinical observation show that the ovulation induction of the Chinese medicine compound composition is mostly single-dominant follicle ovulation, which has little impact on the endometrium, and synchronizes the development of the endometrium and follicles, thereby achieving a higher cycle ovulation rate and clinical pregnancy rate. It has a good curative effect on treating ovulation disorder infertility. Moreover, the toxic and side effects are very low, and the clinical medication is safe and reliable.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine composition, in particular to a compound traditional Chinese medicine composition for treating ovulation disorder infertility and its application. Background technique [0002] The follicle consists of a central egg cell surrounded by granulosa cells and theca cells. Occurrence of follicle is a long process, including many complex changes of oocyte and its surrounding follicle cells. It takes about one year for the development of primordial follicles to the formation of dominant follicles, followed by primordial follicles, preantral follicles (more than 9 months), antral follicles (grade 4 follicles, 60 days), and preovulatory follicles. (25 days, including recruitment, selection, dominant follicle formation) four stages. The follicle formation of the ovary is a highly coordinated physiological process, and the growth and development of follicles are controlled by many factors. It not ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61P15/08
CPCA61K36/076A61K36/23A61K36/284A61K36/39A61K36/40A61K36/43A61K36/537A61K36/725A61K36/73A61K36/738A61K36/804A61K36/8945A61K2236/331A61K2236/39A61K2236/51A61P15/08A61K2300/00
Inventor 刘月红袁春芳
Owner 苏州市吴江区中医医院(苏州市吴江区第二人民医院)
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