Rehmannia decoction pharmaceutical composition and preparation method thereof, and detection method

Abstract

The invention relates to a rehmannia decoction pharmaceutical composition and a preparation method thereof, and a detection method. The pharmaceutical composition consists of the following formula: 0.5-1.5 parts of prepared rehmannia roots, 0.5-1.5 parts of Morinda pulp, 0.5-1.5 parts of cornus officinalis pulp, 0.5-1.5 parts of dendrobium, 0.5-1.5 parts of wine-processed cistanche, 0.5-1.5 partsof prepared common monkshood branched roots, 0.5-1.5 parts of Chinese magnoliavine fruits, 0.5-1.5 parts of cinnamon, 0.5-1.5 parts of poria cocos, 0.5-1.5 parts of dwarf lilyturf tuber, 0.5-1.5 partsof rhizoma acori graminei, 0.5-1.5 parts of milkwort root, 4-6 parts of raw ginger, 3-6 parts of Chinese dates and 0.5-1.5 parts of mint. The composition is prepared by a method including water extraction, freeze drying and the like. The process solves the technical problems that in the prior art, morroniside, loganin and schisandrin are lost due to reduced-pressure drying, and the dry paste powder is granular and hard. The invention determines a specific detection method for qualitative identification, fingerprint spectrum and content determination. The good detection method effectively reflects the advantages and disadvantages of the material reference mass and solves the technical problem that quality detection methods in the prior art are difficult to reflect the advantages and disadvantages of the material reference mass.

Description

technical field

[0001] The invention relates to the field of pharmacy, in particular to a rehmannia root medicinal composition, a preparation method and a detection method. Background technique

[0002] Dihuang Yinzi is the 53rd prescription in the "Catalogue of Ancient Classical Prescriptions" (the first batch) released by the State Administration of Traditional Chinese Medicine in April 2018. Dihuang Yinzi comes from Jin Liu Wansu's "Huang Di Su Wen Xuan Ming Lun Fang". The original text of the prescription is: cooked and dried rehmannia glutinosa, Morinda officinalis (heart removed), dogwood, dendrobium, Cistanche deserticola (soaked in wine, roasted), aconite (cannon), schisandra, laurel, white poria cocos, Ophiopogon japonicus (heart removed), calamus, Polygala (heart removed) is divided into equal parts. The right is the end, three qian per serving, one and a half cups of water, five slices of ginger, one jujube, and mint, all fried together until eight minutes apart...

Examples

Embodiment 1

[0126] Example 1 Prescription: Rehmannia glutinosa 0.5g, Morinda officinalis 0.5g, cornus 0.5g, dendrobium 0.5g, cistanche 0.5g, Paofu tablets 0.5g, Schisandra 0.5g, cinnamon 0.5g, Poria cocos 0.5g, Ophiopogon japonicus 0.5g, Shichangpu 0.5g, polygala 0.5g, ginger 4g, jujube 3g, mint 0.5g.

[0127] Preparation method: (1) Pre-treatment Weigh Rehmannia glutinosa, Morinda officinalis, Cornus officinalis, Dendrobium, Cistanche cistanche, Paofupian, Schisandra chinensis, Cinnamon, Poria cocos, Ophiopogon japonicus, Shichangpu, Polygala, and grind them into coarse powder, Set aside; cut ginger into 2mm-4mm thick slices, and break open jujube when using; set aside;

[0128] (2) Decoction Put the pretreated medicine and peppermint in a 600ml casserole, add 200ml of water, heat with an open fire, cover and decoct, after boiling with a strong fire, decoct with a slow fire for 15 minutes to obtain a decoction;

[0129] (3) Filtrate the decocting liquid with a 200-mesh filter cloth whil...

Embodiment 2

[0133] Example 2 Prescription: Rehmannia glutinosa 0.5g, Morinda officinalis 0.5g, cornus 0.5g, dendrobium 0.5g, cistanche 0.5g, Paofu tablets 0.5g, schisandra 0.5g, cinnamon 0.5g, Poria cocos 0.5g, Ophiopogon japonicus 0.5g, Shichangpu 0.5g, polygala 0.5g, ginger 4g, jujube 3g, mint 0.5g.

[0134] Preparation method: (1) Pre-treatment Weigh Rehmannia glutinosa, Morinda officinalis, Cornus officinalis, Dendrobium, Cistanche cistanche, Paofupian, Schisandra chinensis, Cinnamon, Poria cocos, Ophiopogon japonicus, Shichangpu, Polygala, and grind them into coarse powder, Set aside; cut ginger into 2mm-4mm thick slices, and break open jujube when using; set aside;

[0135] (2) Decoction Put the pretreated medicine and peppermint in a 600ml casserole, add 400ml of water, heat with an open fire, cover and decoct, after boiling with high fire, decoct with a slow fire for 25 minutes to obtain a decoction;

[0136] (3) Filtrate the decoction with a 300-mesh filter cloth while it is hot...

Embodiment 3

[0140] Example 3 Prescription: Rehmannia glutinosa 0.5g, Morinda officinalis 0.5g, cornus 0.5g, dendrobium 0.5g, cistanche 0.5g, Paofu tablets 0.5g, Schisandra 0.5g, cinnamon 0.5g, Poria cocos 0.5g, Ophiopogon japonicus 0.5g, Shichangpu 0.5g, polygala 0.5g, ginger 4g, jujube 3g, mint 0.5g.

[0141] Preparation method: (1) Pretreatment Weigh Rehmannia glutinosa, Morinda officinalis, cornus, dendrobium, cistanche, Paofupian, Schisandra chinensis, cinnamon, Poria cocos, Ophiopogon japonicus, Shichangpu, polygala and grind them into coarse powder, ginger Cut into thick slices of 2mm to 4mm when used, and break the jujube when used;

[0142] (2) Decoction Put the pretreated medicine and peppermint in a 600ml casserole, add 300ml of water, heat with an open fire, cover and decoct, after boiling with a strong fire, decoct with a slow fire for 20 minutes to obtain a decoction;

[0143] (3) Filtrate the decoction with a 300-mesh filter cloth while it is hot and under normal pressure; ...

technical field

[0001] The invention relates to the field of pharmacy, in particular to a rehmannia root medicinal composition, a preparation method and a detection method. Background technique

[0002] Dihuang Yinzi is the 53rd prescription in the "Catalogue of Ancient Classical Prescriptions" (the first batch) released by the State Administration of Traditional Chinese Medicine in April 2018. Dihuang Yinzi comes from Jin Liu Wansu's "Huang Di Su Wen Xuan Ming Lun Fang". The original text of the prescription is: cooked and dried rehmannia glutinosa, Morinda officinalis (heart removed), dogwood, dendrobium, Cistanche deserticola (soaked in wine, roasted), aconite (cannon), schisandra, laurel, white poria cocos, Ophiopogon japonicus (heart removed), calamus, Polygala (heart removed) is divided into equal parts. The right is the end, three qian per serving, one and a half cups of water, five slices of ginger, one jujube, and mint, all fried together until eight minutes apart...

Examples

Embodiment 1

[0126] Example 1 Prescription: Rehmannia glutinosa 0.5g, Morinda officinalis 0.5g, cornus 0.5g, dendrobium 0.5g, cistanche 0.5g, Paofu tablets 0.5g, Schisandra 0.5g, cinnamon 0.5g, Poria cocos 0.5g, Ophiopogon japonicus 0.5g, Shichangpu 0.5g, polygala 0.5g, ginger 4g, jujube 3g, mint 0.5g.

[0127] Preparation method: (1) Pre-treatment Weigh Rehmannia glutinosa, Morinda officinalis, Cornus officinalis, Dendrobium, Cistanche cistanche, Paofupian, Schisandra chinensis, Cinnamon, Poria cocos, Ophiopogon japonicus, Shichangpu, Polygala, and grind them into coarse powder, Set aside; cut ginger into 2mm-4mm thick slices, and break open jujube when using; set aside;

[0128] (2) Decoction Put the pretreated medicine and peppermint in a 600ml casserole, add 200ml of water, heat with an open fire, cover and decoct, after boiling with a strong fire, decoct with a slow fire for 15 minutes to obtain a decoction;

[0129] (3) Filtrate the decocting liquid with a 200-mesh filter cloth whil...

Embodiment 2

[0133] Example 2 Prescription: Rehmannia glutinosa 0.5g, Morinda officinalis 0.5g, cornus 0.5g, dendrobium 0.5g, cistanche 0.5g, Paofu tablets 0.5g, schisandra 0.5g, cinnamon 0.5g, Poria cocos 0.5g, Ophiopogon japonicus 0.5g, Shichangpu 0.5g, polygala 0.5g, ginger 4g, jujube 3g, mint 0.5g.

[0134] Preparation method: (1) Pre-treatment Weigh Rehmannia glutinosa, Morinda officinalis, Cornus officinalis, Dendrobium, Cistanche cistanche, Paofupian, Schisandra chinensis, Cinnamon, Poria cocos, Ophiopogon japonicus, Shichangpu, Polygala, and grind them into coarse powder, Set aside; cut ginger into 2mm-4mm thick slices, and break open jujube when using; set aside;

[0135] (2) Decoction Put the pretreated medicine and peppermint in a 600ml casserole, add 400ml of water, heat with an open fire, cover and decoct, after boiling with high fire, decoct with a slow fire for 25 minutes to obtain a decoction;

[0136] (3) Filtrate the decoction with a 300-mesh filter cloth while it is hot...

Embodiment 3

[0140] Example 3 Prescription: Rehmannia glutinosa 0.5g, Morinda officinalis 0.5g, cornus 0.5g, dendrobium 0.5g, cistanche 0.5g, Paofu tablets 0.5g, Schisandra 0.5g, cinnamon 0.5g, Poria cocos 0.5g, Ophiopogon japonicus 0.5g, Shichangpu 0.5g, polygala 0.5g, ginger 4g, jujube 3g, mint 0.5g.

[0141] Preparation method: (1) Pretreatment Weigh Rehmannia glutinosa, Morinda officinalis, cornus, dendrobium, cistanche, Paofupian, Schisandra chinensis, cinnamon, Poria cocos, Ophiopogon japonicus, Shichangpu, polygala and grind them into coarse powder, ginger Cut into thick slices of 2mm to 4mm when used, and break the jujube when used;

[0142] (2) Decoction Put the pretreated medicine and peppermint in a 600ml casserole, add 300ml of water, heat with an open fire, cover and decoct, after boiling with a strong fire, decoct with a slow fire for 20 minutes to obtain a decoction;

[0143] (3) Filtrate the decoction with a 300-mesh filter cloth while it is hot and under normal pressure; ...

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