The invention discloses a preparation process of
glycine, which comprises
amination,
alkaline hydrolysis,
ammonia discharge acidification, decolorizing, concentration, desalting,
crystallization and recrystallization steps, wherein in the
amination step,
hydroxyacetonitrile and
ammonia water are mixed in a tubular reactor, and a reaction is undergone at the temperature of 50-100 DEG C under the pressure of 0.5-2.0 MPa for 4-10 minutes; and in the
alkaline hydrolysis step, 30-50 percent of
sodium hydroxide solution is added into an
alkaline hydrolysis reactor in advance, an
amination liquid is collected from an amination liquid outlet, a reaction is undergone at the temperature of 60-90 DEG C under the pressure of between -0.01 MPa and -0.09 MPa, and
ammonia in a
system is recovered simultaneously. In the process, the tubular reactor is taken as an amination reactor, so that the
reaction temperature and pressure are raised, the reaction time is shortened, and
raw material decomposition, pyrolytic
polymerization of
aminoacetonitrile and the generation of byproducts are reduced; alkaline
hydrolysis is performed during the collection of the amination liquid, the concentration of an alkaline liquor and the alkaline
hydrolysis temperature are raised simultaneously, and ammonia in the
system is recovered under reduced pressure, so that the alkaline
hydrolysis reaction is more complete, the speed is higher, and the generation of
colored impurities is reduced; and a
mother liquor circular utilizing mode is established, so that the treatment amount of waste
mother liquor is reduced, the product yield is increased, and the production cost is reduced.