83 results about "Hydroxyacetonitrile" patented technology

The invention discloses a preparation process of glycine, which comprises amination, alkaline hydrolysis, ammonia discharge acidification, decolorizing, concentration, desalting, crystallization and recrystallization steps, wherein in the amination step, hydroxyacetonitrile and ammonia water are mixed in a tubular reactor, and a reaction is undergone at the temperature of 50-100 DEG C under the pressure of 0.5-2.0 MPa for 4-10 minutes; and in the alkaline hydrolysis step, 30-50 percent of sodium hydroxide solution is added into an alkaline hydrolysis reactor in advance, an amination liquid is collected from an amination liquid outlet, a reaction is undergone at the temperature of 60-90 DEG C under the pressure of between -0.01 MPa and -0.09 MPa, and ammonia in a system is recovered simultaneously. In the process, the tubular reactor is taken as an amination reactor, so that the reaction temperature and pressure are raised, the reaction time is shortened, and raw material decomposition, pyrolytic polymerization of aminoacetonitrile and the generation of byproducts are reduced; alkaline hydrolysis is performed during the collection of the amination liquid, the concentration of an alkaline liquor and the alkaline hydrolysis temperature are raised simultaneously, and ammonia in the system is recovered under reduced pressure, so that the alkaline hydrolysis reaction is more complete, the speed is higher, and the generation of colored impurities is reduced; and a mother liquor circular utilizing mode is established, so that the treatment amount of waste mother liquor is reduced, the product yield is increased, and the production cost is reduced.

The invention relates to a preparation technology of N-phenylglycinonitrile with the characteristics of economy and environmental protection, and especially provides a technology for mother liquid utilization and wastewater processing in the production of N-phenylglycinonitrile. The preparation technology comprises operations of condensation reaction mother liquid recovery processing, N-phenylglycinonitrile is obtained by carrying out the condensation reaction on aniline, hydroxyacetonitrile and a catalyst in the presence of water (or the mother liquid), the content is greater than 97%, the liquid phase purity is greater than 97%, N-phenylglycinonitrile is a colorless or light yellow transparent crystal, and the yield is greater than 99.5%. The resulting reacted mother liquid can be directly reused in the condensation operation without processing, almost all organic matters can be recovered through physically processing exhaustless wastewater, COD of residual wastewater is less than 200ppm, and the total nitrogen content in the residual wastewater is less than 50ppm. By adopting above optimized technology, the ammonia nitrogen content is reduced, and the COD is reduced, so 75-90% of the mother liquid can be recycled to the condensation reaction and can be repeatedly reused, thereby the wastewater processing amount is reduced; and additionally, the recycle of the mother liquid makes the organic matters in the mother liquid be fully recovered, and yield improvement and cost saving be realized.

This invention provides a method for preparing iminodiacetonitrile. The method comprises: reacting hydroxyacetonitrile and 95-100 wt. % liquid ammonia to obtain iminodiacetonitrile. The method has such advantages as high yield, high product quality, and continuous and stable process.

This invention involves an industrial scale preparation method for hydroxyacetonitrile by using acrylonitrile production byproduct hydrocyanic acid through a synthesis reaction with acetonitrile at the presence of catalyst. The method is characterized by (1) taking acrylonitrile production byproduct hydrocyanic acid as the raw material with content of 95% or above, (2) controlling a molar ratio of hydrocyanic acid : formaldehyde : catalyst at 1 : 1.0~1.5 : 0.001~ 0.015, (3) adding catalyst in formaldehyde while stirring, adding hydrocyanic acid at 0-20DEG C, and reacting at 0~40DEG C for 1~6 h, and (4) adjusting pH of 6 or below with inorganic acid to obtain hydroxyacetonitrile. The invention has the advantages of low cost, product content of 50% or above, simplified aftertreatment, no wastes discharge, and product with formaldehyde and hydrocyanic acid content less than 0.05%. Hydroxyacetonitrile can be used as the intermediates of glycin, malononitrile, and indigo dye to solve transport inconvenience of hydrocyanic acid and geographical limitation of production.

This invention concerns a treatment method for the organic wastewater containing hydroxyacetonitrile, phenylaminoacetonitrile, aniline, diazo value, etc. nitrile-bearing refractory organism. Said method comprises carrying out microelectrolysis under acidic condition, and then adding ferrous sulfate for redox reaction and flocculation process. The mechanism is to make nitriles and CN-NH3-N into small molecules or produce insoluble precipitate through synergetic effect of a series reactions like electrolysis, redox and aeration oxidation, and further decomposition, oxidation and reduction, and remove them through flocculation. The nitriles and hydrogen cyanide like hydroxyacetonitrile and phenylaminoacetonitrile in the water can be removed completely. Aniline can be degraded and removed. CODcr removal percentage is 35-45%.

The present invention relates to process of extracting and purifying hydroxyacetic acid with ester solvent from hydroxyacetic acid aqua obtained through hydrolyzing hydroxyacetonitrile in acid medium. The process includes the steps of treating the hydrolysate, salting out, extracting hydroxyacetic acid, recovering salt and concentrating. The present invention has the technological advantages of simple technological process, low investment, no need of back extraction, facile extractant with stable property, low cost, etc; and may be used in industrial production.

The invention provides a method used for continuous preparation of glycine from hydroxyacetonitrile. According to the method, hydroxyacetonitrile, an ammonia source, and a carbon source are delivered into a device composed of a tubular packed reactor and a kettle-type tandem reactor for synthesis and hydrolysis reaction successively, and then high purity glycine is obtained via distillation, crystallization, separation, and drying. The kettle-type tandem reactor is composed of at least three hydrolysis reaction kettles connected in series via an overflow pipe. Compared with kettle-type batch process in the prior art, the method possesses following advantages: whole flow continuous production of glycine from hydroxyacetonitrile via hydantoin is realized, and no waste liquid is generated.

The invention relates to a preparation method of N,N-dimethylglycine and belongs to the field of chemical engineering. The preparation method comprises the following steps of: preparing N,N-dimethyl amino acetonitrile by taking hydroxyacetonitrile and dimethylamine as raw materials, obtaining an N,N-dimethylglycine crude product by alkalizing the reaction liquid with an inorganic base and neutralizing the reaction liquid with an organic acid on the basis of N,N-dimethyl amino acetonitrile reaction liquid, and finally separating and purifying the N,N-dimethylglycine crude product to obtain the high-quality N,N-dimethylglycine product. The preparation method has the advantages that the raw materials are environmentally-friendly and easily available, reaction conditions are mild, the environmental pollution is little, the after-treatment is simple and easy, the production efficiency is high, and the preparation method is suitable for industrial popularization and application.

The one-step process of preparing hydantoin is that in a trickle bed reactor hydroxy methyl cyanide, CO2 and ammonia as material and solid acid as stuffing and catalyst are prepared into hydantoin through one-step process. Hydroxy methyl cyanide is made to flow into the trickle bed from the top in the flow rate of 100-300 ml/hr, CO2 and ammonia are made to flow into the trickle bed from the bottom in the flow rate of 0.01-0.1 cu m/hr and 0.005-0.06 cu m/hr separately, and through reaction at 40-120 deg.c for 2-5 hr, the reaction liquid is collected and processed through concentration, crystallization, filtering to obtain initial crystal, recrystallization and drying to obtain hydantoin. The synthesis yield may reach 74.85 %.

The invention discloses a high-purity solid sodium sarcosine preparation method. The specific technical scheme comprises the following steps: condensing hydroxyacetonitrile and methylamine to obtain methylaminoacetonitrile; adding sodium hydroxide, and hydrolyzing to obtain sodium methylaminoacetate, namely a sodium sarcosine liquid and free sodium hydroxide mixture; adding hydrochloric acid which is equal to the sodium sarcosine in mol, and neutralizing to obtain a sarcosine and sodium chloride mixture; separating sodium chloride and sarcosine through an electrodialysis membrane separation technology to obtain a high-purity sarcosine solution and an impurity solution; distilling the high-purity sarcosine solution with a multifunctional evaporator to obtain solid crystals, separating to obtain pure sarcosine, and dissolving the sarcosine with 0.5 time of purified water; and dropwisely adding 1:0.98 mol of sodium methoxide at 40 DEG C to precipitate solid sodium sarcosine, performing centrifugal separation to obtain white solids, and drying to obtain the finished product, wherein after the cycle is completed, the mother solution can be recovered through rectifying, and methanol can be for private use or can be sold as a byproduct. The process has peculiar characteristics; and high-purity sodium sarcosine solids can be prepared through the process.

The invention provides a method for continuously preparing glycine. The method comprises the steps that hydroxyacetonitrile is synthesized with an ammonia source and a carbon source in a tubular reactor, and an obtained solution is concentrated to obtain a concentrated solution; then the concentrated solution is fed into kettle type series reactors for a hydrolysis reaction to obtain a glycine-containing solution; and the glycine-containing solution is refined to obtain refined glycine. The method adopts a device composed of the tubular packing reactor and the kettle type series reactors to carry out hydantoin synthesis and the hydrolysis reaction, thereby achieving the purpose of continuous production; and meanwhile, a distillation device is added before the hydrolysis reaction, and the mass concentration of a hydantoin aqueous solution is increased, so that in the same glycine yield, the kettle type series reactors are reduced, the volume of the kettle type reactors is reduced, the reaction time is shortened, and the purpose of the continuous production is well achieved.

The invention belongs to the field of a chemical industry and particularly relates to a method and device for clean production of glycine. The method for clean production of glycine comprises that hydroxyacetonitrile, ammonia, carbon dioxide and water as raw materials undergo a reaction in a special material synthesis reactor, the pressure of the synthesis reactor is reduced to the normal pressureso that a material liquid I is obtained, the material liquid I is heated and hydrolyzed, the pressure of the hydrolysate is reduced to the normal pressure, ammonia is removed so that a material liquid II is obtained, and the material liquid II is treated through a conventional treatment method so that glycine is obtained. The method is environmentally friendly and clean, does not produce by-products, has a high effective conversion rate of hydroxyacetonitrile, greatly improves the glycine yield through a special material, reduces the hydroxyacetonitrile by-products and produces glycine dipeptide to increase corrosion resistance of the material. The device is simple. The method is easy to operate and realizes a low cost.

The invention discloses a synthesis method of monoethanolamine, pertaining to the technical field of organic chemical synthesis. Hydroxyacetonitrile is adopted for carrying out reaction with hydrogen under the presence of a catalyst to obtain the monoethanolamine. Compared with the prior art, the technical proposal has the advantages of full transformation (more than 81 percent) and high yield (more than 70 percent).

The invention relates to a clean production method for co-producing glycine and iminodiacetic acid. The method comprises the steps: performing ammoniation reaction on hydroxyacetonitrile and ammonia under the condition of high temperature to obtain ammoniation liquid, mixing the ammoniation liquid and alkali, performing pyrohydrolysis, performing deamination and decolorizing treatment, performing bipolar membrane electrodialysis to obtain a glycine-sodium aminodiacetate aqueous solution, performing desalting treatment on the obtained glycine-sodium aminodiacetate aqueous solution to obtain a glycine aqueous solution and a sodium aminodiacetate aqueous solution separately, concentrating, crystallizing and drying the glycine aqueous solution to obtain the glycine, and acidifying, crystallizing and drying the sodium aminodiacetate aqueous solution to obtain the iminodiacetic acid. By the method, coproduction of the glycine and the iminodiacetic acid can be realized, the utilization ratio of the raw materials is high, the effective conversion rate of the hydroxyacetonitrile can reach above 93 percent, other organic byproducts are avoided, the product yield is high, the production cost is low, the byproducts are few, the impurities are few, sodium hydroxide can be recycled, the yield of the glycine and the iminodiacetic acid is greatly increased, and the purity of the glycine and the iminodiacetic acid is greatly improved.

The invention provides a method for continuously preparing glycine from hydroxyacetonitrile by a microchannel reactor. The method comprises the following steps: preheating and mixing hydroxyacetonitrile, a carbon source and an ammonia source which serve as raw materials, sequentially performing hydantoin synthesis and hydantoin hydrolysis reaction in the microchannel reactor to obtain a glycine aqueous solution, and performing steam stripping, evaporation and concentration, crystallization, separation, decoloration and drying to obtain the glycine product. Compared with an existing method, themethod realizes continuous preparation of the glycine by taking the hydroxyacetonitrile as the raw material, and has the advantages of short reaction time, few byproducts, high glycine yield and lowpreparation cost.

The invention provides a technological method for jointly preparing liquid hydrogen cyanide and hydroxynitrile. The technological method comprises the steps that a light oil cracking hydrogen cyanide gas mixture is used as a raw material and undergoes an ammonia removal process and a cryogenic process to obtain liquid hydrogen cyanide, wherein in the ammonia removal process, the hydrogen cyanide gas mixture is absorbed with a sulfuric acid aqueous solution; in the cryogenic process, the hydrogen cyanide gas mixture is cooled to minus 10-minus 20 DEG C, after the hydrogen cyanide gas mixture is cooled, a part of the hydrogen cyanide gas becomes liquid to obtain liquid hydrogen cyanide, and the other part of the hydrogen cyanide gas is the tail gas containing hydrogen cyanide; the tail gas containing hydrogen cyanide, which undergoes cryogenic treatment, is absorbed with a formaldehyde aqueous solution containing a catalyst to prepare a hydroxynitrile aqueous solution, and the tail gas absorbed with the formaldehyde aqueous solution directly enters an incinerator to be incinerated. By adopting the technological method, the purification efficiency and the utilization efficiency of hydrogen cyanide can be obviously improved, meanwhile, the energy consumption in the hydrogen cyanide purification process is greatly reduced and can be reduced by 90% at most, and the utilization rate of hydrogen cyanide is more than 99.9%.

* An environmentally-friendly clean production method for continuously synthesizing hydantoin comprises the following steps: reacting an initial raw material hydrocyanic acid with formaldehyde to generate hydroxyacetonitrile, reacting hydroxyacetonitrile in a carbon dioxide and ammonia water system through a continuous reactor to obtain an aqueous solution of hydantoic acid, carrying out acid hydrolysis to obtain hydantoin crystals, and purifying to obtain a highly pure hydantoin product. The combined continuous reactor is adopted to synthesize hydantoin, so the device investment is highly effectively reduced, and the investment efficiency is improved by times; automatic control is very conveniently controlled, the continuity and the stability of production are well guaranteed, the labor cost is saved, and the safe production operationality of the whole process is guaranteed; generation of harmful impurities is well inhibited, decomposition and polymerization of hydroxyacetonitrile and other side reactions are effectively inhibited, and the purity and the yield of the above obtained product are improved; and the method has lower requirements of raw materials, fully and comprehensively utilizes resources, is an environmentally friendly clean production technology, and plays a very active synergistic role in natural environment protection.

The present invention provides process of preparing hydroxyacetic acid with hydroxyacetonitrile. The process includes the following steps; 1. adding proper amount of phosphoric acid into water solution of hydroxyacetonitrile and heating to hydrolyze; 2. concentrating crystallization to eliminate great amount of salt and further desalting with acetone; and 3. vacuum concentrating the acetone water solution to obtain the product hydroxyacetic acid.

The invention relates to a method for preparing and purifying hydroxyacetic acid by using hydroxyacetonitrile as a raw material, which comprises the following steps of: adding sulfuric acid into aqueous solution of the hydroxyacetonitrile, and performing hydrolysis under a heating condition; adding aqueous ammonia into the solution to neutralize excessive residual sulfuric acid; removing most of water in the system; removing salt by using a low-carbon alcohol precipitation method; and removing low-carbon alcohol through reduced pressure distillation to obtain a hydroxyacetic acid product. Themethod has the advantages of simple production device, saved investment cost, low operation cost, high purity of the obtained hydroxyacetic acid product, full recycle of side products, no waste discharge and practicability of large-scale industrialized production.

The purpose of the invention is providing an environmentally-friendly clean technologic production method of highly pure hydantoin. The environmentally-friendly clean technologic production method of highly pure hydantoin comprises the following steps: reacting an initial raw mateiral hydrocyanic acid with formaldehyde to generate hydroxyacetonitrile, reacting hydroxyacetonitrile in a carbonated water system containing ammonia to obtain an aqueous solution of hydantoic acid, carrying out acid hydrolysis to obtain hydantoin crystals, and purifying to obtain a highly pure hydantoin product. The method effectively avoids decomposition and polymerization of hydroxyacetonitrile, well inhibits generation of harmful impurities, realizes a high yield, and allows the purity of the obtained product to be very high; the method reduces the device investment, and well guarantees the operation safety of the whole process; hot water dissolving, heat treatment and hot filtration are adopted in the purifying process, so consumed energy is saved; the above whole technology is a thoroughly environmentally-friendly and clean technology; and the method has lower requirements on raw materials, can fully and comprehensively utilize resources, and plays a very active role in natural environment protection.

The invention relates to a preparation method of hydroxyacetic acid. The preparation method comprises the following steps: performing a hydrolysis reaction on an aqueous solution of hydroxynitrile and a sulfuric acid solution having the mass concentration of 70%-90% at a temperature within the range of 120-140 DEG C, thereby obtaining the mixed solution of hydroxyacetic acid and an acidic salt ammonia sulfate; at the same time of performing an esterification reaction by adding methanol to the mixed solution, distilling out the mixture of methanol, water and methyl hydroxylacetate, and controlling the temperature of the whole process within the range of 110-120 DEG C; adding water to adjust the mass percentage of methyl hydroxylacetate in the mixture to the range of 10%-25%, hydrolyzing methyl hydroxylacetate at a temperature less than or equal to 100 DEG C into hydroxyacetic acid, separating out methanol and water, and recycling separated methanol. According to the preparation method, due to the improvement of the reaction temperatures, the raw material concentration and the preparation method, the reaction time is shortened and the energy consumption and the methanol loss are reduced under the premise of guaranteeing the yield; as a result, the production cost is greatly reduced and the product competitiveness is improved.

The invention relates to a low-cost high-purity 4-(4-aminophenyl)morpholine-3-one (II) preparation method, which comprises: carrying out a substitution reaction on hydroxyacetonitrile and 1,2-dihaloethane to prepare haloethyloxyacetonitrile (IV), carrying out a substitution reaction on the haloethyloxyacetonitrile (IV) and p-nitroaniline (III), carrying out cyclization under an acid condition to form 4-(4-nitrophenyl)morpholine-3-one (V), and carrying out hydrogenation reduction on the 4-(4-nitrophenyl)morpholine-3-one (V) to obtain the 4-(4-aminophenyl)morpholine-3-one (II). According to thepresent invention, the preparation method has characteristics of inexpensive and easily-available raw materials, low cost, simple process route, safety, environmental protection, high selectivity of each designed step and high yield, ensures the preparation of the high-purity 4-(4-aminophenyl)morpholine-3-one, and easily performs the industrial preparation of high-purity rivaroxaban.