239 results about "Trimethyloxamine" patented technology

The invention discloses a liposome vesicle for inhibiting ergothioneine degradation and a preparation method thereof, and belongs to the technical field of cosmetics. According to the ergothioneine liposome and the preparation method thereof disclosed by the invention, by constructing an embedding structure, the ergothioneine is embedded in a phospholipid bimolecular layer of the liposome vesicle, and the outer layer of the phospholipid bimolecular layer is also wrapped with a biocompatible high-molecular polymer shell, so that the ergothioneine is doubly wrapped by the phospholipid bimolecular layer and the high-molecular polymer shell of the ergothioneine liposome; and the degradation of ergothioneine is reduced. And the phospholipid bilayer base material for preparing the liposome vesicles can generate ionic interaction with trimethylamine degraded by the ergothioneine, so that the odor problem of the ergothioneine is effectively reduced.

The invention relates to a trimethylamine methanesulfonate second-order nonlinear optical crystal material and preparation and application thereof, the chemical formula of the crystal material is [(CH3) 3NH] < + > [SO3CH3] <->, the molecular weight is 154.21, the crystal material belongs to an orthorhombic crystal system, and the space group is Pca21 (No.29). According to the present invention, the powder frequency doubling effect of the nonlinear optical crystal [(CH3) 3NH] + [SO3CH3]-under 1064nm laser irradiation is about 0.5 time of the powder frequency doubling effect of the nonlinear optical crystal [(CH3) 3NH] + [SO3CH3]-under 1064nm laser irradiation, phase matching can be achieved, and the ultraviolet absorption cutoff edge is less than 200nm. The crystal material is easy to grow and shows important application value in the aspects of electro-optical modulation, holographic storage elements, frequency doubling devices and the like.

The invention belongs to the technical field of synthetic biology and biological detection and analysis, and particularly relates to a trimethylamine N-oxide biosensor, a genetically engineered bacterium and application of the genetically engineered bacterium. Specifically, a TMAO response type biosensor based on a TorRST atypical two-component system (TCS) is developed in escherichia coli, and the TMAO response type biosensor is optimized. Meanwhile, a TMAO degradation pathway regulated and controlled by a TMAO biosensor is introduced into escherichia coli EcN, so that an engineering probiotic capable of sensitively detecting, regulating and controlling degradation and balance of TMAO is successfully developed. Therefore, the compound can be used for preventing and treating diseases caused by TMAO, and has good practical application value and prospect.

The invention relates to the technical field of water treatment, in particular to a rare earth composite antibacterial scale inhibitor and a preparation method thereof.The preparation method comprises the steps that glycidyl methacrylate, vinylphosphonic acid, N-vinylthiourea and acrylic acid are mixed, a mixed solvent of deionized water and ethyl alcohol is added, nitrogen is introduced after the mixture is stirred and dissolved, azodiisobutyronitrile is added, the mixture is stirred at the constant temperature for a reaction, and the rare earth composite antibacterial scale inhibitor is obtained; the preparation method comprises the following steps: preparing a quadripolymer solution, adding trimethylamine hydrochloride into the quadripolymer solution, carrying out heating and stirring reaction, adjusting the pH value to be neutral to obtain a cationized copolymer solution, dropwise adding the cationized copolymer solution into a cerous nitrate solution, carrying out stirring reaction at room temperature, carrying out centrifugal washing, and carrying out freeze drying to obtain the rare earth composite antibacterial scale inhibitor. The prepared antibacterial scale inhibitor is remarkable in effect, metal ions can be combined in scale inhibition, growth of scale crystals is prevented, the rare earth ions and the copolymer are synergistically antibacterial, and the antibacterial scale inhibitor is durable, stable, good in dispersity and capable of adapting to complex environments.

The invention provides a covalent organic framework proton exchange membrane, a preparation method thereof and a high-temperature proton exchange membrane fuel cell. The preparation method comprises the following steps: dispersing 5-bromomethyl-dimethyl isophthalate and trimethylamine in alcohol to obtain a reaction solution, and performing water bath and rotary evaporation to obtain a first intermediate; dispersing the first intermediate in a hydrazine hydrate / ethanol mixed solution, reacting at 80-100 DEG C for 24-48 hours, and recrystallizing to obtain a second intermediate; dispersing the second intermediate and silver chloride in water, and carrying out inert gas reaction at 80-100 DEG C for 10 hours to obtain a quaternary ammonium type amine monomer; dissolving a quaternary ammonium type amine monomer and glacial acetic acid in water to obtain an amine monomer solution; the preparation method comprises the following steps: dissolving 1, 3, 5-benzenetricarboxaldehyde and 1, 4-dioxane in mesitylene to obtain an aldehyde monomer solution; adding the aldehyde monomer solution above the amine monomer solution to obtain an interfacial polymerization reaction system, reacting at 16-40 DEG C for 7 days, and filtering to obtain a nanosheet dispersion liquid; dropwise adding the dispersion liquid into a suction filtration container, performing vacuum suction filtration to form a membrane, and then adding a phosphoric acid solution to enable phosphoric acid molecules to enter the membrane to obtain the covalent organic framework proton exchange membrane.

The invention provides a low-energy-consumption preparation process of tetramethylammonium bicarbonate, and relates to the technical field of chemical synthesis. The preparation process comprises the following steps: inputting trimethylamine, dimethyl carbonate and a solvent methanol into a reactive distillation tower, carrying out a quaternization reaction to generate methyl carbonate tetramethylammonium, and carrying out a hydrolysis reaction on a first liquid phase obtained by rectification and water vapor to generate TMAB; the reacted material is input into a methanol removal tower for rectification, an obtained second gas phase is heated and pressurized, one part of the second gas phase is input into a subsequent methanol recovery tower, the other part of the second gas phase exchanges heat with water to generate steam, the steam is input into a tower kettle of the methanol removal tower, and high-purity methanol is extracted from the side of the methanol recovery tower. The number of reaction equipment is reduced, and the energy utilization rate is increased; the steam grade is improved by utilizing a heat pump technology, and steam latent heat is integrated between the methanol removal tower and the methanol recovery tower through thermal coupling, so that the overall process energy consumption is remarkably reduced while the product quality is ensured.

This invention discloses a method for preparing a high-temperature resistant, strongly basic anion exchange resin, belonging to the field of ion exchange resins. The method includes three steps: First, white spheres with a crosslinking degree of 6-10 undergo a chloromethylation reaction by sequentially adding zinc dichloride and tin tetrachloride to improve the uniformity of the chloromethyl group distribution in the chlorospheres; second, the chlorospheres undergo an etherification reaction using tetrabutylammonium bromide as a phase transfer catalyst, and the dropping rate of sodium methoxide solution is controlled to improve the etherification conversion rate; finally, the etherification product undergoes a quaternization reaction with a trimethylamine aqueous solution to obtain the strongly basic anion exchange resin. This invention, by selecting the degree of crosslinking and optimizing the catalyst addition method for chloromethylation and the sodium methoxide dropping rate for the etherification reaction, results in a more uniform distribution of quaternary ammonium groups in the resin, significantly improving the ion exchange capacity and high-temperature resistance of the resin.

The invention provides an aqueous zinc ion battery electrolyte, a preparation method thereof and a zinc ion battery, and belongs to the technical field of aqueous zinc ion batteries. The aqueous zinc ion battery electrolyte comprises an additive, an inorganic zinc salt and a solvent, the additive comprises at least one of trimethylamine substituted by 1-3 substituent groups, benzene and C3-C10 straight-chain alkane, and the substituent groups comprise phosphonic acid groups or phosphinic acid groups; the solvent comprises a sodium chloride aqueous solution. By adopting the additive with a specific structure and the solvent containing the sodium chloride aqueous solution, the cycle performance of the zinc negative electrode in the water-based zinc ion battery can be remarkably improved, and the service life of the water-based zinc ion battery is prolonged.

Disclosed is a method of synthesizing a compound selected from the group consisting of C-alkyl glycosides, C-alkenyl glycosides, C-heteroaryl glycosides, Se-glycosides and S-glycosides, the method comprising: a. Reacting a natural unprotected sugar with a 2-chloro-1, 1, 1, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3 The method comprises the following steps: reacting 1, 3-dimethylimidazoline chloride (DMC) and a mixture of heteroaryl mercaptan and trimethylamine (Et3N) in a mixture of water and dialkane to generate heteroaryl glycosyl thioether; b, under the irradiation of a blue light LED, in the presence of Hantzsch ester (HE), 1, 4-diazabicyclo [2.2. 2] octane (DABCO) and DMSO, heteroaryl glycosyl thioether and a reagent are subjected to light-induced cross coupling, and the compound is generated.

The invention discloses a chicken freshness detection method and system combining a colorimetric gel label and a convolutional neural network, and belongs to the technical field of food safety detection. An indicating gel dot matrix label is prepared from curcumin, anthocyanin and betacyanin, the optimal load concentration of curcumin, anthocyanin and betacyanin is optimized and determined, and sensitive color response is generated to volatile biogenic amine gas such as dimethylamine and trimethylamine; gel label images are collected, the images are divided into fresh samples, secondary fresh samples and decayed samples in combination with the TVB-N content, the samples are subjected to data enhancement and then input into an OfficientNet-B0 model for training, and efficient classification is achieved. According to the method, a detection system combining the natural pigment-based multi-channel colorimetric gel and the lightweight convolutional neural network is constructed, lossless, rapid and intelligent detection of the freshness of the fresh chicken is realized, and a green and efficient solution is provided for real-time monitoring of the freshness of food and application of a mobile terminal.

The invention discloses a lactobacillus brevis SMF L6 strain for improving the characteristic flavor of fermented fish and application thereof, and belongs to the technical field of aquatic product processing. According to the method disclosed by the invention, low-temperature fermentation is carried out by utilizing a sake lactobacillus wide cloth SMF L6 direct vat set fermentation inoculant to regulate and control the flavor; the method can effectively promote the production of flavor substances such as n-hexyl alcohol, eudesmol, 2-ethylhexyl alcohol, 4-platycladi alcohol, linalool, 4-terpene alcohol, alpha-terpilenol, piperonone, beta-myrcene, alpha-terpinene, D-limonene, beta-phellandrene, gamma-terpinene and the like in the fermented fish. The content of pungent smell and fishy smell substances such as acetic acid, p-xylene, o-xylene, trimethylamine, methyl mercaptan and carbon disulfide is reduced.

The invention discloses a preparation method of water-soluble naphthyl nut arene and construction of a molecular beaker. The method comprises the following steps: reacting 2, 7-dibromonaphthalene (compound 1) with 2, 5-dimethoxyphenylboronic acid to generate a compound 2; demethylating through boron tribromide to obtain a compound 3; then reacting with dihaloalkane to generate a compound 4; then carrying out cyclization with methylal to obtain H1; then reacting with trimethylamine to obtain H2; then, H2 and sodium phytate are used for constructing a molecular beaker system; according to the method, a series of water-soluble naphthyl nut arenes with different alkane chain lengths and different halide ions are prepared, and an efficient molecular beaker system is constructed. The molecular beaker system has the advantages of being simple and convenient to synthesize, low in cost, adjustable in height, capable of effectively improving the binding capacity with specific guest molecules and the like.

The invention relates to a silicon carbide-boron nitride three-dimensional heat conduction framework material and a preparation method and application thereof.The preparation method comprises the steps that boron nitride nanosheets are prepared into dispersion liquid, the pH of the dispersion liquid is adjusted through ammonia, then an organic silicon source is added for a reaction, and a precursor is obtained; the precursor comprises a boron nitride nanosheet and SiO2 nanoparticles loaded on the surface of the boron nitride nanosheet; mixing the precursor, polyamide acid and trimethylamine in a solvent, and performing freeze drying treatment to obtain composite aerogel; and sequentially carrying out thermal imidization treatment, carbonization treatment and carbon thermal reduction reaction on the composite aerogel to obtain the silicon carbide-boron nitride three-dimensional heat-conducting framework material. According to the preparation method, SiC nanowires are efficiently connected with BNNS to form a microstructure welded continuous heat-conducting network, and the prepared silicon carbide-boron nitride three-dimensional heat-conducting framework material has excellent heat conductivity, electric insulativity and flexibility when being used as a thermal interface material and is wide in application prospect.

The invention discloses a polyaluminum chloride-based flocculant as well as a preparation method and application thereof, belongs to the technical field of preparation of flocculants, and aims at solving the technical problem that the flocculation performance and the stability of a flocculant in the prior art need to be further improved. The surface charges of iron-based particles are adjusted through sodium citrate, so that the problem of particle agglomeration is effectively avoided, the coating uniformity of microgel is improved, and the specific surface area of the material is increased; abundant cation sites are introduced into the trimethylamine modified chitosan, so that the electrostatic adsorption capacity of the microgel on anion pollutants is remarkably enhanced, and meanwhile, the electrical property and the stability of a system are improved; the addition of sodium metasilicate further promotes the modified PAC to form a stable Al-O-Si bridging structure, the material is endowed with good three-dimensional skeleton strength and composite interface stability, the three components cooperate with each other and play key roles in particle dispersity, charge construction and skeleton stability, and finally, an efficient, stable and storable composite flocculation system is constructed.

The invention discloses a method for preparing electronic grade tetramethyl ammonium bicarbonate. The method comprises the following steps: respectively pumping dimethyl carbonate and trimethylamine as raw materials and methanol as a solvent into a modified ion exchange resin tower for demetalization, mixing in a mixing kettle, and then entering a tandem reaction kettle; reaction materials are fed from the bottom of the previous stage, discharged from the upper part of the reactor and fed into the next stage of reactor, and are catalyzed and dehydrated in the last stage of reactor to further remove metal ions; feeding into a flash tank after passing through a multi-stage reaction kettle, separating excessive methanol and dimethyl carbonate, and refluxing to the mixing kettle; materials at the bottom of the flash tank enter a hydrolysis rectifying tower, methanol at the top partially flows back, and the product tetramethyl ammonium bicarbonate is obtained at the bottom of the rectifying tower. The reaction is stable, the reaction is driven by pressure difference, the number of moving equipment is minimum, continuous operation and automatic control are achieved, meanwhile, metal ion control in the raw material and synthesis process is achieved, and the quality of the electronic-grade tetramethylammonium bicarbonate is improved.

The present invention discloses a method for synthesizing azoxystrobin, which includes: in a water-oil system of an organic solvent and an aqueous solution of trimethylamine, the compound shown in Formula I reacts with 2-cyanophenol to obtain azoxystrobin; wherein, the molar ratio of the compound shown in Formula I to trimethylamine is 1:(0.96-2). The synthesis method of the present invention has higher reaction efficiency, does not generate CO2, avoids the risk of entrainment and overflow of materials, reduces side reactions, reduces solid waste emissions, and is green and environmentally friendly. The present invention does not need to use solid sodium carbonate or potassium carbonate, and the material reaction system is an oil-water reaction system, so the reaction efficiency is greatly improved, and the yield can also be maintained above 95%. It can take into account both efficiency (timeliness) and yield, and is easy to realize continuous reaction, providing technical support for intelligent and unmanned production; and trimethylamine can be recycled, reducing the use of one raw material, and thus does not require cumbersome treatment of mixed salts and their wastewater, and the energy consumption is significantly reduced.

The invention relates to the technical field of organic chemical synthesis, and discloses a continuous production process of a cationic etherifying agent, which comprises the following steps: taking trimethylamine hydrochloride and epoxy chloropropane as raw materials; the method comprises the following six steps: raw material pretreatment, premixing, continuous reaction, continuous separation, refining and product storage: mixing and dissolving trimethylamine hydrochloride and a solvent, preparing a catalyst solution, uniformly mixing the three materials through a static mixer, feeding into a multi-stage tubular reactor, and carrying out segmented temperature control continuous reaction, and performing flash evaporation solvent removal and rectification on the reaction product to obtain a crude product, and performing ion exchange impurity removal and reduced pressure distillation refining to finally obtain a high-purity product. The method solves the problems of low yield and more byproducts in the traditional process, and is suitable for industrial large-scale production.

The invention belongs to the technical field of nano material application, and particularly relates to a nitrogen-rich carbon nitride gas-sensitive material, a gas-sensitive sensor and a preparation method and application of the nitrogen-rich carbon nitride gas-sensitive material and the gas-sensitive sensor. The ammonia leakage in the environment or the ammonia content in the expired gas of the human body can be accurately detected; and harmful gases such as ethanol, methanol, isopropanol, triethylamine, acetone, trimethylamine, nitrogen dioxide and the like can be detected. The nitrogen-rich carbon nitride gas-sensitive material is prepared into a gas-sensitive sensor, and the gas-sensitive sensor has the advantages of high ammonia responsivity, good selectivity, good stability, strong anti-interference performance and the like at room temperature. The gas sensor does not need to be heated during use, a conventional gas sensor heating step is omitted, and the gas sensor can be directly placed in a normal-temperature environment for operation; and different substrate materials can be used for constructing rigid and flexible substrate sensors, and the application method is simple, easy to operate, good in effect and wide in application prospect.

The invention relates to a method for producing methylamine by a generally exothermic gas-phase reaction of methanol and ammonia as reactants in the presence of a heterogeneous catalyst at a pressure in the range of 15 to 35 bar. The reactants are evaporated in one or more heat exchangers and superheated prior to being fed to the reactor, wherein the heat exchangers in turn are heated with a stream of hotter product gas from the reactor. In addition to methylamine (monomethylamine, dimethylamine, and trimethylamine), the product gas stream contains unconverted reactants, water, and any other reaction by-products. To control the reactor inlet temperature and limit it to a temperature in the range of 350 DEG C to 410 DEG C, a suitable quenching liquid is introduced into the hot product gas stream prior to feeding the hot product gas stream to a heat exchanger for heating the reactants. Evaporation and overheating of the added quenching liquid removes the corresponding amount of energy extracted from the hot product gas stream, with the result of efficient and rapid cooling of the hot product gas stream. As a result, the temperature difference between the cold side and the hot side of the heat exchanger is small, which means less energy is transferred to the reactant stream, and thus its reactor inlet temperature can be adjusted or limited.

The invention discloses a mitochondrial / lysosome dual-targeting viscosity response AIE probe as well as a preparation method and application thereof. According to the probe, tetraphenylethylene (TPE) is used as an AIE light-emitting framework, and two flexible side chains containing hydrophilic units are introduced by utilizing the excellent structural modifiability of the TPE. The tail end of each side chain is modified with a trimethylamine group, quaternary ammonium salt cations derived from the trimethylamine group have localized positive charges, and combination with water molecules can be enhanced through ion-dipole interaction, so that the water solubility and biocompatibility of the molecules are effectively improved. Based on the design, the invention provides the AIE polymer probe which is constructed by taking TPE as a core and taking an amphiphilic flexible chain as a functional unit. The probe can establish a three-dimensional linear relationship among drug action time-regional viscosity-fluorescence lifetime (t-eta-tau) by capturing fluorescence lifetime signals inside and outside cells, so as to realize visual detection and quantitative analysis of average viscosity change of mitochondria and lysosome in the mitochondrial autophagy process.

The invention relates to a method for preparing an imine covalent organic framework gas sensor at normal temperature by virtue of a catalyst. A device involved in the method is composed of three sensors, a ceramic substrate and six electrodes. The recognition effect on trimethylamine, ethidene diamine and ammonia gas can be realized at room temperature (25 DEG C). The preparation method of the sensor array is simple, the sensor array has the advantage of performing non-contact identification detection at room temperature, and the practicability of the sensor is greatly enhanced. In addition, it is also found that preparation of a covalent organic framework by means of a catalyst at normal temperature and application of the covalent organic framework to gas-sensitive sensing detection are very promising means.

The invention belongs to the technical field of preparation of tetraisopropyl alcohol-based ethylenediamine, and particularly relates to a catalyst for preparing tetraisopropyl alcohol-based ethylenediamine as well as a preparation method and application of the catalyst. The catalyst is formed by chelating two amine nitrogen atoms with aluminum ions by taking an Al < 3 + > center as tetra-coordination and 1, 1-dimethoxytrimethylamine as a ligand, and has a structure as shown in a formula I in the specification. The two-component composite catalyst is formed on the basis of coordination and chelation of the organic metal compound and the organic amine, the organic metal compound can promote the antistatic performance of the tetraisopropyl alcohol ethylenediamine, and the organic amine can promote the compatibility of the tetraisopropyl alcohol ethylenediamine and a high polymer material, so that the antistatic property of the tetraisopropyl alcohol ethylenediamine is improved. Compared with a pure organic amine catalyst, the composite catalyst has the advantages of high reaction activity, side reaction inhibition, improvement of the conversion rate and selectivity of tetraisopropanolethylenediamine, no need of separation from the product, promotion of the product, reduction of the impurity separation problem in the subsequent process, reduction of the reaction pressure, low equipment requirement and reduction of the equipment investment.

The invention relates to a method for green, mild and efficient synthesis of methylamine hydrochloride based on photocatalysis. According to the method, methanol and ammonium chloride which are wide in source and low in price are used as raw materials, under the anaerobic condition, a Pd / TiO2 photocatalyst is adopted for a photocatalytic reaction, and target methylamine hydrochloride products including monomethylamine hydrochloride, dimethylamine hydrochloride and trimethylamine hydrochloride are synthesized in one step. Compared with traditional industrial synthesis, the photocatalysis technology has the advantages of mild reaction conditions, simplicity and convenience in operation, environmental friendliness and the like, provides an efficient and feasible way for green synthesis of methylamine hydrochloride, and has a wide application prospect.

The invention belongs to the technical field of reproductive medicine and clinical metabolism intervention, and particularly relates to a group of markers for diagnosing unexplained recurrent abortion and application thereof. Aiming at the clinical pain point that unexplained recurrent abortion (URSA) lacks accurate metabolic typing diagnosis indexes and targeted treatment means, based on detection of a large number of clinical samples and verification of cell experiments, direct association between down-regulation of levels of choline related metabolites and trimethylamine oxide (TMAO) of decidua tissues and the RSA is disclosed for the first time; the core effect of TMAO in-situ synthesis of decidua stromal cells (DSC) in regulation and control of the decidualization process is determined; meanwhile, an RSA indication screening system of joint detection of serum creatinine and decidua choline metabolism is constructed, a targeted TMAO targeted intervention scheme is formed in a matched mode, a diagnosis and treatment closed loop of RSA from precise typing to targeted treatment is achieved, and a brand new technical path is provided for clinically solving the URSA diagnosis and treatment problem.

The invention provides a screening method of a targeted drug for inhibiting accumulation of trimethylamine and / or trimethylamine-N-oxide. The screening method comprises the following steps: determining an action target on a metabolic pathway of trimethylamine and / or trimethylamine-N-oxide; if the target is protein, preliminarily screening candidate components based on the three-dimensional structure of the target; the candidate component is validated to confirm the targeted drug. According to the method, large-scale screening of targeted drugs aiming at targets can be achieved, the targeted drugs inhibit accumulation of trimethylamine and / or trimethylamine-N-oxide in the body by influencing the metabolic pathway of trimethylamine and / or trimethylamine-N-oxide, side effects are small, and the normal metabolic process of the human body is prevented from being influenced.

Provided is a synthesis method for azoxystrobin, comprising: in a water-oil system of an organic solvent and an aqueous solution of trimethylamine, a compound represented by formula I reacts with 2-cyanophenol to obtain azoxystrobin, wherein the molar ratio of the compound represented by formula I to trimethylamine is 1:(0.96-2). The synthesis method has high reaction efficiency, does not produce CO2, avoids the risks of entrainment and overflow, reduces the generation of side reactions and solid waste emissions and is environmentally friendly. In addition, the method does not require the use of solid sodium carbonate or potassium carbonate, and the material reaction system is an oil-water reaction system, so that the reaction efficiency is greatly improved, and the yield can also be maintained at 95% or more, thereby taking both the efficiency (timeliness) and the yield into account and easily achieving continuous reaction, and thus providing technical support for intelligent and unmanned production. Moreover, since trimethylamine can be recycled, the use of one raw material is reduced, and further there is no need for complicated treatment for mixed salts and waste water thereof, thereby significantly reducing the energy consumption.

The invention relates to the technical field of degumming agents, and discloses a preparation process of a degumming agent for a solar photovoltaic silicon wafer. The degumming agent comprises the following components in percentage by weight: 2-8% of tetramethylammonium hydroxide, 3-6% of organic alcohol amine, 0.5-1.5% of alkyl glycoside, 0.2-0.8% of a chelating agent, 0.5-3% of a functional additive and the balance of deionized water, the chelating agent is sodium gluconate; the functional additive comprises a sodium silicate corrosion inhibitor, a thickening agent and a penetrating agent; the preparation method comprises the following steps: S1, adding trimethylamine and epoxy chloropropane into tetrahydrofuran, carrying out stirring reaction at 60-65 DEG C for 8-15 hours, and removing a solvent to obtain a cationized intermediate; s2, adding the cationized intermediate into water, adding sodium carboxymethyl cellulose, uniformly stirring, heating and pressurizing to 120-130 DEG C, stirring and reacting for 8-12 hours, and removing the solvent to obtain the modified sodium carboxymethyl cellulose.

The invention provides a composition. The composition is prepared from probiotics, a plant extract and acceptable auxiliary materials according to a specific content ratio. Wherein the probiotics comprise the following components: Weizmannia coagulans AUSA001, Lactobacillus plantarum AUSA002, Bifidobacterium longum subsp. Longum FL006, and the probiotics comprise the following components: the Weizmannia coagulans AUSA001, the Lactobacillus plantarum AUSA002, the Bifidobacterium longum subsp. Longum FL006, the Lactobacillus plantarum AUSA002 and the Bifidobacterium longum subsp. Longum FL006. The plant extract comprises a kudzuvine root extract, a grape seed extract and a turmeric extract. The composition has a synergistic effect, can reduce the content of human intestinal trimethylamine and serum trimethylamine oxide, and is used for prevention or adjuvant therapy of related diseases.

The application relates to the field of catalytic synthesis, and discloses a methylamine synthesis method, which comprises the following steps: reacting methanol and ammonia in the presence of a zeolite catalyst treated by an organic alkali to generate a methylamine-containing stream; the acid amount of the zeolite catalyst treated by the organic alkali is 200-400 mu mol.g ‑1 The methylamine synthesis method can reduce the selectivity of trimethylamine in the reaction product, reduce the content of trimethylamine in the product, and ensure high methanol conversion rate.

This utility model belongs to the field of trimethylamine removal technology, specifically relating to a trimethylamine removal device, including a deamination tower bottom liquid cooler, a deamination tower reboiler, and a deamination tower condenser. The deamination tower reboiler and condenser are both connected to the deamination tower bottom liquid cooler via pipelines. A pressure relief pipe is connected to the deamination tower bottom liquid cooler, and a connecting nozzle is threaded onto the inner side of the upper opening of the pressure relief pipe. A pressure relief port is fixedly connected to the top of the connecting nozzle. By setting up the deamination tower bottom liquid cooler, reboiler, and condenser, online removal of trimethylamine is achieved. The pressure relief pipe on the deamination tower bottom liquid cooler utilizes a coordinated design of a tapered tube, elastic band, and plug to achieve rapid pressure relief of the trimethylamine gas. When the pressure inside the tower exceeds a threshold, the gas pushes open the plug to release pressure. After the pressure decreases, the elastic band automatically pulls back the plug to seal, requiring no manual intervention.