361 results about "Trimethyloxamine" patented technology

Aqueous heavy duty liquid laundry detergent compositions useful for laundering fabrics and providing cleaning and softening benefits. Such detergent compositions contain at least 5%, by weight of the composition, of a surfactant component; from about 0.1% to about 10% of a quaternary ammonium fabric-softening agent having the formula wherein R1 and R2 are individually selected from the group consisting of C1-C4 alkyl, C1-C4 hydroxy alkyl, benzyl, and —(C2H4O)xH where x has a value from about 2 to about 5; X is an anion; and (1) R3 and R4 are each a C8-C14 alkyl or (2) R3 is a C8-C22 alkyl and R4 is selected from the group consisting of C1-C10 alkyl, C1-C10 hydroxy alkyl, benzyl, and —(C2H4O)xH where x has a value from about 2 to about 5; and such compositions contain less than 10 ppm of trimethylamine and dimethylamine impurities.

Endoplasmic reticulum stress has been found to be associated with obesity. Therefore, agents that reduce or prevent ER stress may be used to treat diseases associated with obesity including peripheral insulin resistance, hypergylcemia, and type 2 diabetes. Two compounds which have been shown to reduce ER stress and to reduce blood glucose levels include 4-phenyl butyric acid (PBA), tauroursodeoxycholic acid (TUDCA), and trimethylamine N-oxide (TMAO). Other compounds useful in reducing ER stress are chemical chaperones such as trimethylamine N-oxide and glycerol. The present invention provides methods of treating a subject suffering from obesity, hyperglycemia, type 2 diabetes, or insulin resistance using ER stress reducers such as PBA, TUDCA, and TMAO. Methods of screening for ER stress reducers by identifying agents that reduce levels of ER stress markers in ER stressed cells are also provided. These agents may find use in methods and pharmaceutical compositions for treating obesity-associated diseases.

A reduced odor composition is composed of at least one cationic polygalactomannan or a derivative of cationic polygalactomannan having a weight average molecular weight (Mw) having a lower limit of 5,000 and an upper limit of 200,000, a light transmittance in a 10% aqueous solution of greater than 80% at a light wavelength of 600 nm, a protein content of less than 1.0% by weight of polysaccharide, and a trimethylamine content of less than 25 ppm in a 10% aqueous solution of the polymer. This composition is prepared by treating the polymer with reagents that reduce the molecular weight of the polymer, removing the water-insoluble solid material, and removing odorous components, including trimethylamine (TMA) and other amines and low molecular weight components from the aqueous phase to produce a polymer that when used in a functional system such as household care, personal care or pet care products has reduced or no odor at acidic, neutral, or alkaline pH values.

The invention relates to a filter additive material for selectively reducing the hydrocyanic acid emission amount in the mainstream smoke of cigarettes and a preparation method thereof. The filter additive material for selectively reducing the hydrocyanic acid emission amount in the mainstream smoke of cigarettes is characterized in that the filter additive material is a novel material that can effectively absorb acidic gas and is obtained by chemically modifying a porous material and introducing different alkali groups. The preparation method of the filter additive material comprises the following steps: respectively carrying out surface chemical modification on the selected porous carrier material with trimethylamine chloride acethydrazide or (2-bromomethyl)trimethyl ammonium bromide, soaking with sodium hydroxide solution, washing with water and drying to obtain the modified porous material containing ammonium hydroxide group. Adding the material in a cigarette filter rod can reducethe hydrocyanic acid content in the mainstream smoke of cigarette by more than 30%, and no negative influence is caused on the taste quality of cigarette, thus achieving the purpose of selectively reducing harm.

The invention designs and synthesizes a cationic water-soluble column [5] aromatic hydrocarbon compound. The structure of the compound has a column frame containing five benzene rings, and five trimethylamine groups are respectively connected to upper and lower edges of the column frame. The compound is column aromatic hydrocarbon containing multiple recognition sites, has good solubility in water, and can be complexed with silver ions by cationic trimethylamine groups in a pure water phase to form a stable complex. Experiments indicate that in the water solution of the cationic water-soluble column aromatic hydrocarbon, only addition of Ag<+> is capable of remarkably reinforcing the ultraviolet absorption peak of the cationic water-soluble column aromatic hydrocarbon at 293nm, and addition of other cationic ions cannot change ultraviolet absorption of the cationic water-soluble column aromatic hydrocarbon at 293nm in the water solution. Therefore, the column aromatic hydrocarbon has a good selective ultraviolet recognition capability for Ag<+>, can be used as an Ag<+> acceptor molecule to detect silver ions in a pure water phase. Titration experiments indicate that the lowest detection limit of column aromatic hydrocarbon for Ag<+> is 1.25*10<-5>M.

The invention discloses a method for detecting aromatic amine in cigarette mainstream smoke by using a gas chromatography-tandem mass spectrometry. The method is characterized by comprising the following steps of: catching aromatic amine compounds in a particulate matter in the cigarette mainstream smoke by using a Cambridge filter; extracting by using hydrochloric acid solution, washing by usingdichloromethane, reducing by using sodium hydroxide and then extracting by using normal hexane, and performing derivatization by using pentafluoropropionic anhydride and trimethylamine hydrochloride;and concentrating and detecting by using the gas chromatography-tandem mass spectrometer (GC-MS / MS) so as to measure the content of the main aromatic amine compounds in the cigarette mainstream smoke. Compared with the conventional method for analyzing the aromatic amine in the cigarette mainstream smoke, the analysis and measurement method has the advantage of simplifying the pretreatment of a sample along with higher sensitivity, high experimental repetitiveness and recovery rate and applicability to analysis of a large batch of samples.

The invention provides a method for synthesizing quaternary ammonium salt ionic liquid by microwave radiation heating, which comprises the following steps: mixing tertiary amine compounds (N,N-dimethylethanolamine, trimethylamine or triethanolamine) and halohydrocarbon compounds (allyl chloride, n-butyl chloride, n-butyl bromide, octadecyl chloride) with a molar ratio of 1:1.05-1:2 under a microwave radiation heating condition, putting the mixture into a microwave reactor to perform a microwave reaction with an adjusted microwave power of 100 W-400 W, a heating temperature of 30 DEG C-80 DEG C, and reaction time of 1 min-15 min so as to obtain a crude product, removing residual halohydrocarbon compounds in the crude product to obtain quaternary ammonium salt ionic liquid with halogens as anions; the halohydrocarbon compounds are chlorinated hydrocarbon compounds or brominated hydrocarbon compounds. The preparation method of the invention is simple, does not require the addition of any solvent except reaction raw materials, and can prepare high-purity quaternary ammonium salt ionic liquid simply, efficiently, rapidly, and economically.

The present invention describes a process for the industrial production of L-carnitine, comprising the enantioselective reduction of an alkyl 4-chloro-3-oxobutyrate or 4-chloro-3-oxobutyramide. The optically active 3-hydroxy derivative thus obtained is reacted with trimethylamine, obtaining crude L-carnitine, which is then finally purified. The catalyst used for the reduction is a complex of ruthenium bound to a penta-atomic bis-heteroaromatic system. The reduction reaction, performed in controlled conditions of hydrogen pressure, substrate concentration, temperature, and substrate: catalyst molar ratio, enables 4-chloro-3-hydoxybutyrate or 4-chloro-hydroxybutyamide to be obtained in a high yield. The process described, which leads to L-carnitine being obtained, is easily applicable on an industrial scale.

The invention relates to a catalytic light-emitting sensitive material used for monitoring benzene and trimethylamine. The catalytic light-emitting sensitive material is nano powder material which consists of Ag atom doped Y2O3, Fe2O3 and ZrO2; the mass percent ranges of the components are as follows: Ag accounts for 5-15%; Y2O3 accounts for 15-25%; Fe2O3 accounts for 40-50%; ZrO2 accounts for 20-30%. A preparation method of the catalytic light-emitting sensitive material comprises the following steps: co-dissolving yttrium salt, ferric salt and zircon salt in a citric acid aqueous solution, adjusting pH value by using ammonia water in a stirring state, standing and aging, then drying and fully grinding, roasting in a chamber electric furnace, and obtaining Y2O3, Fe2O3 and ZrO2 powder material; dissolving an appropriate amount of silver nitrate and maltose in water, adding the powder material which is dispersed by ultrasonic wave into the water by continuously stirring, drying, heating and reducing, cooling, grinding and obtaining Ag atom doped Y2O3, Fe2O3 and ZrO2 nano powder. A benzene-trimethylamine catalytic light-emitting sensor, which is manufactured by using the catalytic light-emitting sensitive material, is wide in linear range, good in selectivity and high in sensitivity, and is capable of monitoring benzene and trimethylamine in the air on line without influence of coexistence substance.

The invention belongs to the technical field of adsorption materials, and discloses a modified biomass adsorber as well as a preparation method and application thereof. The preparation method comprises the following steps: cleaning a straw raw material, soaking and then drying the straw raw material, and performing pulverization; then performing alkalization pretreatment to remove water, and performing crosslinking treatment by using epoxy chloropropane; removing excessive epoxy chloropropane from the crosslinked straw, and performing quaternarization with a trimethylamine aqueous solution; filtering out the trimethylamine aqueous solution, and cleaning and drying an obtained modified straw product so as to obtain the modified biomass adsorber. The preparation method disclosed by the invention is low in preparation cost and environment-friendly, can be used for removing NO3<-> and PO4<3-> from nutrition-enriched water, is high in adsorption efficiency, and is relatively good in adsorption effect at the pH of 3 to 9.

STA-20, a molecular sieve having a new framework type, is described. STA-20AP (as prepared) can have an alkyl amine, such as trimethylamine, and 1,6-(1,4-diazabicyclo[2.2.2]octane) hexyl cations (from diDABCO-C6) as SDAs. A lower alkyl ammonium hydroxide, such as tetrabutylammonium hydroxide, can be used as a pH modifier for making SAPO STA-20. A calcined product, STA-20C, formed from as made STA-20 is also described. Methods of preparing STA-20, activating STA-20 by calcination, and metal containing calcined counterparts of STA-20 are described along with methods of using STA-20 and metal containing calcined counterparts of STA-20 in a variety of processes, such as treating exhaust gases and converting methanol to olefins are described.

The invention discloses an anti-swelling swelling shrinkage agent and a preparation method thereof, and solves the problem that the existing clay inhibitor cannot have anti-swelling and swelling shrinkage properties at the same time. The anti-swelling and swelling shrinkage agent provided by the invention is composed of 65ml of 30% hydrochloric acid, 100ml of 33% trimethylamine solution, 0.5g of a cetyl trimethyl ammonium bromide solid and 45g of an epoxy chloropropane liquid. The anti-swelling and swelling shrinkage agent not only has inhibiting effect on the expansion of clay, but also can shrink the expanded clay particles, so as to effectively improve the permeability of an oil reservoir.

The invention discloses a method for preparing betaine hydrochloride. The method comprises the following steps of: performing a quaterisation reaction on trimethylamine and chloroactic acid under the action of sodium iodide serving as a nucleophilic substitution catalytic; adding calcium oxide or calcium hydroxide; heating for discharging trimethylamine completely; acidifying with sulfuric acid to obtain a calcium sulfate-betaine hydrochloride solution; and filtering a reaction liquid, concentrating and crystallizing to obtain the betaine hydrochloride. In the method, an efficient catalyst is adopted, so that the reaction is rapid and complete; meanwhile, expensive alkalis and hydrochloric acid are not required, and only cheap calcium oxide and sulfuric acid are required; and meanwhile, no side reaction is performed, the yield is greatly increased, and the yield of the betaine hydrochloride is over 99 percent counted by chloroacetic acid, so that the cost of the method is over 20 percent lower than that of the conventional process; and the preparation period is short, the reaction conditions are mild, a product is separated easily and sufficiently, three wastes are not generated, and raw materials and a solvent can be used circularly, so that the method has higher economic efficiency and environment friendliness.

The invention belongs to the technical field of clinical biological sample detection, and particularly relates to a method for detecting trimethylamine oxide, choline, betaine, creatinine and L-carnitine in a biological sample through high-throughput liquid chromatography-tandem mass spectrometry. The method can simultaneously detect five substances in a biological sample, and has the advantages of high accuracy, high sensitivity, high specificity, small required sample volume, simple sample pretreatment, good tolerance and the like.

A phosphonic choline containing hydroxy is prepared through adding trimethylamine to hydroxy-contained phosphohetrocyclo pentane and anhydrous acetonitrile, sealing, reacting at 40-90 deg.C for 24-72 hr, and purifying. A biologic material containing phosphonic choline is prepared through adding diisocyanate, organic solvent, organotin as catalyst and biological film to container protected by nitrogen gas, reacting at 25-100 deg.C for 1-5 hr, and washing with organic solvent. Said biological material features high mechanical performance and high anticoagulating function.

The invention discloses a deodorizing material of a refrigerator and a preparing method of the deodorizing material. Manganese sulfate, potassium permanganate, a copper-bearing precursor and a magnesium-bearing precursor are configured into a solution, after a mixing reaction is carried out, a molecular sieve is added for dipping, the molecular sieve is dried and roasted after being dipped, active carbon and the roasted molecular sieve are formed together in an extruding mode, and the deodorizing material of the refrigerator is prepared. The deodorizing material of the refrigerator has a good effect of removing methyl mercaptan, ethyl mercaptan, trimethylamine, ammonia and hydrogen sulfide and is combined with the active carbon so that the peculiar smells in the refrigerator can be removed through chemical adsorption and physical adsorption, and the defects of chemical adsorption and the defects of physical adsorption compensate for each other.

The present invention describes a process for the industrial production of L-carnitine, comprising the enantioselective reduction of an alkyl 4-chloro-3-oxobutyrate or 4-chloro-3-oxobutyramide. The optically active 3-hydroxy derivative thus obtained is reacted with trimethylamine, obtaining crude L-carnitine, which is then finally purified. The catalyst used for the reduction is a complex of ruthenium bound to a penta-atomic bis-heteroaromatic system. The reduction reaction, performed in controlled conditions of hydrogen pressure, substrate concentration, temperature, and substrate: catalyst molar ratio, enables 4-chloro-3-hydoxybutyrate or 4-chloro-hydroxybutyamide to be obtained in a high yield. The process described, which leads to L-carnitine being obtained, is easily applicable on an industrial scale.

The invention discloses a fishy flavor agent for a feed and a preparation method of the fishy flavor agent. The fishy flavor agent contains the following perfume materials in percentage by weight: 0.5-2% of glycine betaine, 1-3% of trimethylamine, 0.1-2% of 2-methyl-3-sulfydrylfuran, 0.1-1% of pyrrolidine, 0.1-1% of piperidine, 0.1-2% of phenylethylamine, 0.01-1% of 2-acetylpyridine, 0.1-1% of furanone, 1-3% of ethyl maltol, 1-3% of 2-acetylpyrazine, 1-3% of 2,3,5-trimethylpyrazine, 0.01-2% of 3-methylthiopropanal, 30-70% of fishy smell reactants and 10-60% of glycerol triacetate. The fishy flavor agent is prepared by carrying out enzymolysis on animal wastes, then adding reducing sugars to carry out Maillard reaction, and then, adding artificial synthetic essence to blend. The fishy flavor agent has the advantages that the animal wastes are reasonably utilized, the preparation process is simple, and the product is strong in fragrance, stable and easy to store.

The invention discloses a regeneration technology of a recovered methylamine solution and a device thereof, belonging to the technical field of chemical separation engineering. The device disclosed herein comprises a separation tower, an absorption tower, a gas-liquid separation pot and a series of matched heat-exchange units. The technology disclosed herein is characterized by carrying out pressurized rectification on a recovered impurity-containing methylamine solution in the separation tower to produce high-purity methylamine gas; absorbing gaseous methylamine by using the absorbent in the absorption tower, removing dimethylamine, trimethylamine and other impurities which have a boiling point that is between the boiling points of methylamine and the solvent from the recovered methylamine solution to ensure the concentration and the purity of the regenerated methylamine solution. According to the invention, the recycling problem of the recovered methylamine solution is overcome, the pollution to environments caused by methylamine exhaust gas can be prevented, the enterprise economic benefit is raised, the elasticity of the technology operations is large, and the technology disclosed herein is very important for recycling the recovered methylamine and the industrialization thereof.

The invention discloses a characterization method for detecting freshness of a shrimp product, relating to a detection method of the freshness. The characterization method comprises the steps of: simultaneously measuring TMA (timethylamine) and TMAO (trimethylamine oxide) in the shrimp product by utilizing a picric acid colorimetric method; obtaining a molar ratio of TMA / TMAO by carrying out data processing; carrying out correlation analysis on a measured value of volatile basic nitrogen of the shrimp product and the molar ratio of TMA / TMAO, so as to obtain a dependent equation; and substituting a standard value of the volatile basic nitrogen for evaluating a grade of the freshness into the dependent equation, so as to obtain a standard value of the molar ratio of timethylamine / trimethylamine oxide for evaluating a freshness degree of the shrimp product. According to the characterization method for detecting the freshness of the shrimp product, the disadvantages that the subjectivity, complexity and accuracy are low and the like in the conventional detection method at present can be improved, and the accuracy and the objectivity of an aquatic product detection method are remarkably improved; and the characterization method has the advantages that the cost is lowered, the detection is sensitive and the measuring effect is good.

The invention discloses a preparation technique of medium / high-viscosity dimethyl silicone oil, which comprises the following steps: swelling chloromethylated polystyrene balls in a trimethylamine water solution, and adding perfluoro tertiary amine; supporting potassium hydroxide to obtain a composite catalyst, and adding octamethylcyclotetrasiloxane (D4) and hexamethyl disiloxane (MM) into the reaction kettle; and after the reaction finishes, filtering to recover the catalyst, extracting under reduced pressure and recovering the low-boiling-point substances, thereby obtaining the methyl silicone oil product.

The invention relates to a method for determining the content of trimethylamine in egg yolk by headspace gas chromatography. The determination method is as follows: potassium hydroxide is used as a catalyst, added to the egg yolk liquid, ultrasonically, and under airtight conditions, trimethylamine is hydrolyzed and completely released from the egg yolk tissue; then trimethylamine hydrochloride is used as a standard solution, and the top Blank injection, gas chromatographic analysis. Calculate the content of trimethylamine in the sample according to the standard curve of standard substance concentration and peak area. The invention is superior to common chemical analysis methods, and has the characteristics of short analysis time, simple operation and high accuracy.

The invention discloses a method for preparing a mineral inhibitor for barite, which comprises the steps of: putting epoxy chloropropane and trimethylamine into a flat bottom flask according to the molar ratio of the epoxy chloropropane to the trimethylamine being 1-2:2-6; putting the flat bottom flask into an ice bath; closely stirring the mixture to react for 2 to 3h; standing and layering the obtained product, then taking a supernatant liquid as an intermediate product for standby; putting starch into the flat bottom flask; adding the intermediate product into the starch, taking HCl solution as a catalyst, and adding Na2SO4 which accounts for 0.1 to 0.2 percent of the mass of the total system; putting the mixture in a water bath with a temperature of between 70 and 85 DEG C, and heating the mixture to react for 3 to 4h; and then drying to obtain a powdery substance, namely the inhibitor. The inhibitor can effectively inhibit the barite in fluorite ore concentrate, can improve the grade of the fluorite ore concentrate, and has simple flow, small medicament dosage and low energy consumption.

The invention discloses a preparation method for preparing anhydrous betaine through chemical synthesis. High-purity anhydrous betaine of which the purity is over 99.9 percent is produced by performing procedures including neutralizing, substituting, concentrating, primary desalting, secondary desalting, evaporating, crystalizing, centrifuging, drying and the like on chloroacetic acid, sodium carbonate and trimethylamine serving as major raw materials through a process for combining electrodialysis desalting, evaporative desalting and a boiling dryer. In the process, the original methanol dehydration and double-core dryer drying equipment is eliminated, and obtained metahydrate betaine is directly dried by using a boiling drier, so that cost on each ton can be saved by about 1,200 yuan, and the yield is increased by 3 tons per day.

A heparan sulfated derivative is prepared from heparan sulfated by sulphating. A preparation method comprises: swelling heparan sulfated by anhydrous dimethyl formamide, adding a sulfur trioxide-trimethylamine complex, heating for esterification, dissolving, dialyzing, freeze-drying precipitation components of the reactant by distilled water, then dissolving by sodium chloride solution, precipitating by ethanol, centrifuging, removing a supernatant, drying, and then obtaining sulphated heparan sulfated. The heparan sulfated derivative can inhibit activities of tumor cells and umbilical vein endothelial cell proliferation.

The invention relates to a dual-cation bactericide, a preparation method and application thereof. The dual-cation bactericide has the following structural formula, wherein R is saturated alkane of which the C number is 12 to 18. The method comprises the following steps of: adding 1,000 to 1,400 parts of water and 190 to 295 parts of alkyl methyl secondary amine into a reaction kettle, heating to the temperature of between 50 and 55 DEG C, adding 90 to 105 parts of epoxy chloropropane, keeping the temperature of between 60 and 65 DEG C for 3 to 6 hours, cooling to the temperature of between 40 and 45 DEG C, adding 120 to 136 parts of hydrochloric acid and 60 to 67 parts of trimethylamine, heating to the temperature of between 60 and 65 DEG C, keeping the temperature for 2 to 5 hours, cooling to the temperature of between 40 and 45 DEG C, adding 123 to 131 parts of benzyl chloride, heating to the temperature of between 70 and 85 DEG C, keeping the temperature for 4 to 8 hours, and thus obtaining the dual-cation quaternary ammonium salt bactericide, wherein each raw material in the reaction is proportioned in part by weight. The dual-cation bactericide has a better bactericidal effect, is low in cost, and has economical efficiency and feasibility; and the raw materials are readily available.

The invention discloses a hydrolysis resistant Si-C-Si type cation organosilicon surfactant. The hydrolysis resistant Si-C-Si type cation organosilicon surfactant is prepared by performing reaction on the chloropropy carbosilane, N-methylimidazole, N-methylpyrrolidine, N, N-dimethylethanolamine, trimethylamine, triethylamine or pyridine. The prepared surfactant has good surface activity and a certain germicidal activity and can be used in the fields such as pesticide adjuvants, drug sustained release, functional nano-materials and textile processing aids.

The invention discloses a preparation method of an anion exchange chromatography stationary phase using highly-crosslinked glycidyl methacrylate-divinyl benzene microspheres as a matrix. The preparation method includes: adopting a dispersion polymerization method to prepare monodispersed linear polystyrene seed microspheres; adopting a two-step seed swelling method to prepare highly-crosslinked glycidyl methacrylate-divinyl benzene copolymer microspheres; using methylamine, dimethylamine, trimethylamine, diethylamine, triethylamine and 1, 4-butane dioldiglycidyl ether as reaction raw materials to modify the highly-crosslinked glycidyl methacrylate-divinyl benzene copolymer microspheres to prepare the anion exchange chromatography stationary phase.

The invention relates to a highly selective sensitive material for trimethylamine and hydrogen sulfide, which is characterized in that the material is the composite powder material composed of Dy2O3,MoO3 and ZrO2. The preparation method comprises the steps of uniformly mixing acetic acid aqueous solution of dysprosium salt and isocitric acid aqueous solution of zircon salt; directly adding ammonium molybdate crystals into the mixture; adding carboxymethylcellulose to form a thick colloidal solution; and aging, drying, calcinating at two stages and naturally cooling to acquire the composite powder material composed of Dy2O3, MoO3 and ZrO2. A gas sensor manufactured by using the sensitive material provided by the invention can measure the trace trimethylamine and hydrogen sulfide in the airwith high sensitivity on the scene without being interfered by other common coexisting molecules.