28 results about "Trimethyloxamine" patented technology

Provided is a synthesis method for azoxystrobin, comprising: in a water-oil system of an organic solvent and an aqueous solution of trimethylamine, a compound represented by formula I reacts with 2-cyanophenol to obtain azoxystrobin, wherein the molar ratio of the compound represented by formula I to trimethylamine is 1:(0.96-2). The synthesis method has high reaction efficiency, does not produce CO2, avoids the risks of entrainment and overflow, reduces the generation of side reactions and solid waste emissions and is environmentally friendly. In addition, the method does not require the use of solid sodium carbonate or potassium carbonate, and the material reaction system is an oil-water reaction system, so that the reaction efficiency is greatly improved, and the yield can also be maintained at 95% or more, thereby taking both the efficiency (timeliness) and the yield into account and easily achieving continuous reaction, and thus providing technical support for intelligent and unmanned production. Moreover, since trimethylamine can be recycled, the use of one raw material is reduced, and further there is no need for complicated treatment for mixed salts and waste water thereof, thereby significantly reducing the energy consumption.

This utility model belongs to the field of trimethylamine removal technology, specifically relating to a trimethylamine removal device, including a deamination tower bottom liquid cooler, a deamination tower reboiler, and a deamination tower condenser. The deamination tower reboiler and condenser are both connected to the deamination tower bottom liquid cooler via pipelines. A pressure relief pipe is connected to the deamination tower bottom liquid cooler, and a connecting nozzle is threaded onto the inner side of the upper opening of the pressure relief pipe. A pressure relief port is fixedly connected to the top of the connecting nozzle. By setting up the deamination tower bottom liquid cooler, reboiler, and condenser, online removal of trimethylamine is achieved. The pressure relief pipe on the deamination tower bottom liquid cooler utilizes a coordinated design of a tapered tube, elastic band, and plug to achieve rapid pressure relief of the trimethylamine gas. When the pressure inside the tower exceeds a threshold, the gas pushes open the plug to release pressure. After the pressure decreases, the elastic band automatically pulls back the plug to seal, requiring no manual intervention.

This invention discloses an EGCG supramolecular compound with antioxidant, liver-protective, and fat-reducing effects, its preparation method, and composition. The supramolecular compound is formed by non-covalent bonding between epigallocatechin gallate (EGCG) and ligand molecules containing trimethylamine and carboxyl groups; the supramolecular compound has a co-amorphous structure; the ligand molecules containing trimethylamine and carboxyl groups are betaine, ergothioneine, or L-carnitine. This invention can solve the problems of low stability and bioavailability of EGCG. It can significantly improve the solubility of EGCG and its ligands, including betaine, L-carnitine, and ergothioneine, reduce the hygroscopicity of EGCG and its ligands, including betaine, L-carnitine, and ergothioneine, and enhance the stability and bioavailability of EGCG and its ligands, including betaine, L-carnitine, and ergothioneine.

The present application relates to the technical field of chemical separation, and discloses a methylamine separation and purification system and method, which can efficiently destroy hydrogen bond association system by accurately controlling flash evaporation pressure, temperature and material residence time, can recover the extraction water after removing trace organic impurities, can recover the extraction agent polarity and selectivity, can guarantee the stable separation efficiency of trimethylamine, can cut off the cross-unit pollution path from the source, can slow down the tower scaling and improve the mass transfer efficiency, can simultaneously match the whole process parameter monitoring system, can collect the operation parameters of each tower, product purity, impurity removal rate and hydrogen bond dissociation rate, can calculate the system running cycle and failure probability based on the data, and can propose the product purity stability and system energy consumption optimization strategy, so as to dynamically control the operation parameters of the whole link such as deamination, extraction, separation and recovery, and guarantee the stable output of high-purity methylamine product and the long-period continuous operation of the system.

The present application discloses a synthesis method for azoxystrobin, comprising a step of: reacting a compound of Formula I with 2-cyanophenol in a water-oil system of an organic solvent and an aqueous solution of trimethylamine to obtain azoxystrobin, wherein a molar ratio of the compound of Formula I to trimethylamine is 1:(0.96-2). The synthesis method of the present application has advantages of high reaction efficiency, no CO2 generation, avoidance of the risk of entrained overflow, reduced secondary reactions, reduced solid waste emissions, and environmental friendliness. Use of solid sodium carbonate or potassium carbonate is avoided and the material reaction system is an oil-water reaction system. The reaction efficiency is significantly improved and the yield can reach 95% or above. Both efficiency (timeliness) and yield can be taken into account, and continuous reactions can be realized easily, providing technical support for intelligent, unmanned production.

This invention discloses a 4-(formaldehyde oxime)-fluoro-2-quinolinone compound and its synthetic method, belonging to the fields of organic synthetic chemistry and medicinal chemistry. Using halogen-containing fluoro-N-(2-vinylphenyl)acetamide compounds as starting materials, this invention utilizes a visible light-induced tandem cyclization reaction to obtain 4-(formaldehyde oxime)-fluoro-2-quinolinone compounds in high yield. This invention employs greener and cleaner visible light as an energy source and uses inexpensive and readily available tert-butyl nitrite and trimethylamine borane as dual-role reagents (hydrogen transfer reagent and oxime source) and halogen atom transfer reagent, respectively, avoiding the use of expensive transition metal catalysts. The raw materials are simple and readily available, the process is environmentally friendly, and the target product yield is high.

The application belongs to the technical field of materials, and particularly relates to a metal organic framework loaded zinc ricinoleate composite material and a preparation method and application thereof. The metal organic framework loaded zinc ricinoleate composite material comprises MOFs as a carrier, and zinc ricinoleate is loaded on the inner surface and / or outer surface of pores of the MOFs through a surface activator of the MOFs in physical adsorption and / or chemical action. The comprehensive performance of adsorption and reaction removal of volatile organic compounds (VOCs) such as formaldehyde, and odor pollutants such as ammonia and trimethylamine of the composite material prepared by the application is improved.

The present application relates to a kind of monodisperse hybrid silica microspheres containing sulfhydryl shell and its preparation and application in chromatographic stationary phase. Specifically, with non-porous silica microspheres as matrix, (3-mercaptopropyl) triethoxysilane and tetraethyl silicate are used as functional monomers, N,N-dodecanamide and N-(2,3-dioleoyl) propyl-N,N,N-trimethylamine (chloride) are used as double-template pore-forming agent, under the action of catalyst urea, sol-gel reaction occurs, a radial hybrid shell is constructed on the surface of non-porous silica microspheres, and core-shell type hybrid silica microspheres with sulfhydryl shell are formed. The preparation method adopted is low in cost, few in steps, mild in reaction condition, suitable for large-scale preparation, the obtained hybrid microspheres shell contains a large number of sulfhydryl functional groups, which is convenient for subsequent functional modification, and the good monodispersity of microspheres and unique core-shell structure are very suitable for being used as liquid chromatography stationary phase.

This invention discloses a method for establishing a model of oligoasthenospermia using trimethylamine N-oxide. The method involves injecting trimethylamine N-oxide into the peritoneal cavity of an animal to obtain the oligoasthenospermia model. This invention successfully established a mouse model of oligoasthenospermia by intraperitoneal injection of trimethylamine N-oxide (TMAO) into male mice. This provides new ideas and clues for in-depth research on the pathogenesis of oligoasthenospermia and for researchers studying male reproductive health. It also has significant scientific and medical value for understanding the pathogenesis of male infertility, developing new therapies, evaluating treatment effects, and promoting related clinical research.

The present invention relates to devices comprising conjugates, and their use in depleting at least one amine, in particular ammonia, from a body fluid. The present disclosure also provides systems, apparatuses, conjugates, plurality of conjugates, and methods. More particularly, the conjugate comprises a particle bonded to at least one linker comprising a chain of n carbon atoms covalently bonded to m carbonyl groups; and at least one trapping agent A covalently bonded to the mth carbonyl group, wherein n is an integer in the range of 5 to 15, and m is an integer in the range of 5 to 10, wherein the trapping agent A is characterized by having the ability to capture or bind an amine. In some optional embodiments, the amine is at least one of methylamine, dimethylamine, or trimethylamine. In some embodiments, the linker of the conjugate of the disclosed devices comprises a straight-chain alkane and m carbonyl groups.

The present invention provides an inhibitor of trimethylamine-responsive receptors that is suitable for deodorizing trimethylamine odor by suppressing the response of trimethylamine-responsive receptors. [Solution] In a preferred example, the inhibitor of the trimethylamine-responsive receptor includes at least one selected from the group consisting of trans-cinnamaldehyde, 3-(1,3-benzodioxol-5-yl-2-methylpropanal, 3-(4-tert-butylphenyl)propanal, trans-2-hexenal, citral, Litsea cubeba fruit oil, 3-methyl-5-phenylpentan-1-ol, 4,8-dimethyl-4,9-decadienal, undecanal, ethyl dehydrocyclogeranate, and 4-[(octahydro-4,7-methano-5H-indene)-5-ylidene]butanal.

Polyfenol(s) and / or metabolite(s) thereof, and / or precursor(s) to trimethylamine, and / or trimethylamine-N-oxide (TMAO), or a composition comprising polyfenol(s) and / or metabolite(s) thereof and / or precursor(s) to trimethylamine, and / or 5 trimethylamine-N-oxide, for use in a method of identifying whether or not an individual has small intestinal bacterial overgrowth (SIBO), is / are disclosed.

The application belongs to the technical field of pharmaceutical preparations, and particularly relates to a rivaroxaban tablet, a preparation method and use. The rivaroxaban tablet comprises a rivaroxaban inclusion compound, lactose, starch, low-substitution hydroxypropyl cellulose and magnesium stearate. The rivaroxaban is packaged by using trimethylamine modified methyl cellulose as a packaging material, and the preparation process is optimized. The problem of low drug loading and low encapsulation efficiency of the rivaroxaban inclusion compound in the prior art is solved. The rivaroxaban tablet with a rivaroxaban inclusion compound with high drug loading and high encapsulation efficiency is provided, and the delivery efficiency of the rivaroxaban inclusion compound is improved. Through verification, the rivaroxaban tablet provided by the application has high dissolution rate, few impurities and stability.

In a preferred example, this trimethylamine-responsive receptor inhibitor comprises at least one component selected from the group consisting of trans-cinnamaldehyde, 3-(1,3-benzodioxol-5-yl-2-methylpropanal, 3-(4-tert-butylphenyl)propanal, trans-2-hexenal, citral, Litsea Cubeba fruit oil, 3-methyl-5-phenylpentan-1-ol, 4,8-dimethyl-4,9-decadienal, undecanal, ethyl dehydrocyclogeranate, and 4-[(octahydro-4,7-methano-5H-inden)-5-ylidene]butanal.

The application relates to a preparation method of modified alkyl aluminum oxyalkane and application thereof. The method comprises the following steps: (1) cooling alkyl aluminum or an alkyl aluminum solution in a reaction kettle; (2) feeding nitrogen dioxide gas into the reaction kettle to react with the alkyl aluminum or the alkyl aluminum solution; and (3) obtaining modified alkyl aluminum oxyalkane and trimethylamine after post-treatment. The method has the advantages of short process, easy amplification, stable and controllable reaction process, simultaneous preparation of modified alkyl aluminum oxyalkane and by-product trimethylamine, high purity of the prepared modified alkyl aluminum oxyalkane, high catalytic activity of the modified alkyl aluminum oxyalkane combined with a single-center catalyst, and application in the field of olefin polymerization.

The application provides a preparation method of quaternary ammonium base and application thereof in dye synthesis. Propylene oxide is added into trimethylamine, nucleophilic ring-opening addition reaction of trimethylamine to the epoxy group of propylene oxide is carried out, hydroxypropyltrimethylammonium hydroxide is obtained, then the hydroxypropyltrimethylammonium hydroxide is used to replace sodium hydroxide in the dye synthesis process, inorganic salt is not introduced into the reaction system, and after the reaction is completed, multiple water washing and salt removal are not needed, so that the wastewater amount and salt load can be obviously reduced.

This invention discloses a perilla compound water-retaining agent and its application in deodorizing and retaining water in aquatic products, belonging to the field of food processing technology. The water-retaining agent uses perilla extract as its core component, combined with compound cyclodextrin and 3,4-dimethoxy-3,5,7-trihydroxyflavone. The compound cyclodextrin is prepared from citrate monoglyceride compound cyclodextrin. Through single-factor experiments combined with electronic nose-assisted analysis, the optimal application process was determined using the fishy smell value and color difference value of marine fish as optimization indicators. When applied to marine fish processing, the phenolic substances in the perilla extract can inhibit lipid and protein oxidation, the compound cyclodextrin can specifically encapsulate fishy smell substances, and 3,4-dimethoxy-3,5,7-trihydroxyflavone jointly enhances water retention performance, achieving effective deodorization, significantly reducing the content of trimethylamine and nonenal, improving color stability, and optimizing processing quality. It is suitable for various aquatic product processing scenarios.

The present application provides a kind of lignin quaternary ammonium salt cation emulsifier and its preparation method, emulsified asphalt and its application, belong to fine chemical field.The preparation method of lignin quaternary ammonium salt cation emulsifier provided by the present application includes the following steps: mixing trimethylamine hydrochloride, epichlorohydrin and water, ring-opening reaction is carried out under alkaline condition, and intermediate is obtained;The intermediate is mixed with sulfomethylated lignin, and the reaction is carried out to obtain lignin quaternary ammonium salt cation emulsifier.The present application uses lignin as raw material to prepare lignin quaternary ammonium salt cation emulsifier, raw material cost is low, and the lignin quaternary ammonium salt cation emulsifier is fast, and dispersion performance is good, and durability is good, can be widely used in the preparation of emulsified asphalt.

This invention relates to the field of chemical fiber technology, and particularly to a highly flexible side-by-side bicomponent fiber and its preparation method, comprising the following steps: First, a quaternary ammonium salt modifier containing dual-terminated amine groups is obtained by reacting trimethylamine with 2-chloro-4,6-diamine-1,3,5-triazine. Then, this modifier is subjected to a polycondensation reaction with compound (I) of formula I to obtain a modified polyamide. The modified polyamide is then bonded to a polyetheramine via amide bonds to obtain a copolymer. Finally, the copolymer is spun with PBT using a dual-metering pump system to obtain a side-by-side bicomponent fiber; wherein R1 is a C9-11 aliphatic chain. The side-by-side bicomponent fiber of this invention exhibits good softness, elastic recovery, antibacterial ability, antistatic ability, and flame retardant properties.

The present technology relates to an improved method for manufacturing anion exchange membranes. The method uses trimethylamine gas for amination of polymer films. The process involves placing polymer film pieces or a roll with thin spacer in a pressure vessel, removing air by applying vacuum, and then filling the vessel with trimethylamine gas at about 1 barg pressure and at about 30° C. temperature. After amination, residual trimethylamine is removed by vacuum and optionally by heat treatment. This gas-based approach eliminates membrane swelling and wrinkling issues associated with aqueous trimethylamine solutions, improves diffusion rates, reduces waste generation, and allows for more efficient and scalable production processes, including the ability to aminate complete rolls of polymer film. The resulting membrane maintains its structural integrity and is more suitable for assembly into electrochemical device stacks.

This invention provides a trimethylamine recovery device, relating to the field of trimethylamine wastewater recovery technology. The device includes vertical grooves formed on the inner walls of both sides of a filter box, with a filter screen slidably inserted between the two grooves. The filter device also includes a sliding groove on the top surface of the filter screen and a sliding plate inside it. A limiting rod is fixedly installed on the surface of the sliding plate, and a limiting hole is formed on one side of the inner wall of one of the vertical grooves. The filter device also includes a support plate fixedly installed on the top surface of the filter screen, with a spring fixedly installed between the support plate and the sliding plate. This invention allows the filter screen to be installed inside the filter box, thereby filtering out ribbon-like impurities from the wastewater before it enters the reactor body, preventing damage to the stirring components.

This invention relates to an aromatic deodorizing composition, its preparation method, and its application, belonging to the technical field of daily chemical products. The invention provides an aromatic deodorizing composition, comprising, by weight percentage, 0.1-0.7 wt% of plant-derived active monomers and 0.05-6 wt% of a stationary phase, wherein the stationary phase comprises zinc gluconate and pyrrolidone carboxylic acid. This invention, by combining a stationary phase containing zinc gluconate and pyrrolidone carboxylic acid with plant-derived active monomers to form an aromatic deodorizing composition, purposefully reduces odor molecules (isovaleric acid, ammonia, trimethylamine, hydrogen sulfide), inhibits Escherichia coli and lipid peroxidation, thereby achieving the effect of aromatic deodorization and odor removal.