343 results about "Trimethyloxamine" patented technology

Aqueous heavy duty liquid laundry detergent compositions useful for laundering fabrics and providing cleaning and softening benefits. Such detergent compositions contain at least 5%, by weight of the composition, of a surfactant component; from about 0.1% to about 10% of a quaternary ammonium fabric-softening agent having the formula

wherein R₁ and R₂ are individually selected from the group consisting of C₁-C₄ alkyl, C₁-C₄ hydroxy alkyl, benzyl, and —(C₂H₄O)_xH where x has a value from about 2 to about 5; X is an anion; and (1) R₃ and R₄ are each a C₈-C₁₄ alkyl or (2) R₃ is a C₈-C₂₂ alkyl and R₄ is selected from the group consisting of C₁-C₁₀ alkyl, C₁-C₁₀ hydroxy alkyl, benzyl, and —(C₂H₄O)_xH where x has a value from about 2 to about 5; and such compositions contain less than 10 ppm of trimethylamine and dimethylamine impurities.

Endoplasmic reticulum stress has been found to be associated with obesity. Therefore, agents that reduce or prevent ER stress may be used to treat diseases associated with obesity including peripheral insulin resistance, hypergylcemia, and type 2 diabetes. Two compounds which have been shown to reduce ER stress and to reduce blood glucose levels include 4-phenyl butyric acid (PBA), tauroursodeoxycholic acid (TUDCA), and trimethylamine N-oxide (TMAO). Other compounds useful in reducing ER stress are chemical chaperones such as trimethylamine N-oxide and glycerol. The present invention provides methods of treating a subject suffering from obesity, hyperglycemia, type 2 diabetes, or insulin resistance using ER stress reducers such as PBA, TUDCA, and TMAO. Methods of screening for ER stress reducers by identifying agents that reduce levels of ER stress markers in ER stressed cells are also provided. These agents may find use in methods and pharmaceutical compositions for treating obesity-associated diseases.

A reduced odor composition is composed of at least one cationic polygalactomannan or a derivative of cationic polygalactomannan having a weight average molecular weight (Mw) having a lower limit of 5,000 and an upper limit of 200,000, a light transmittance in a 10% aqueous solution of greater than 80% at a light wavelength of 600 nm, a protein content of less than 1.0% by weight of polysaccharide, and a trimethylamine content of less than 25 ppm in a 10% aqueous solution of the polymer. This composition is prepared by treating the polymer with reagents that reduce the molecular weight of the polymer, removing the water-insoluble solid material, and removing odorous components, including trimethylamine (TMA) and other amines and low molecular weight components from the aqueous phase to produce a polymer that when used in a functional system such as household care, personal care or pet care products has reduced or no odor at acidic, neutral, or alkaline pH values.

The invention designs and synthesizes a cationic water-soluble column [5] aromatic hydrocarbon compound. The structure of the compound has a column frame containing five benzene rings, and five trimethylamine groups are respectively connected to upper and lower edges of the column frame. The compound is column aromatic hydrocarbon containing multiple recognition sites, has good solubility in water, and can be complexed with silver ions by cationic trimethylamine groups in a pure water phase to form a stable complex. Experiments indicate that in the water solution of the cationic water-soluble column aromatic hydrocarbon, only addition of Ag<+> is capable of remarkably reinforcing the ultraviolet absorption peak of the cationic water-soluble column aromatic hydrocarbon at 293nm, and addition of other cationic ions cannot change ultraviolet absorption of the cationic water-soluble column aromatic hydrocarbon at 293nm in the water solution. Therefore, the column aromatic hydrocarbon has a good selective ultraviolet recognition capability for Ag<+>, can be used as an Ag<+> acceptor molecule to detect silver ions in a pure water phase. Titration experiments indicate that the lowest detection limit of column aromatic hydrocarbon for Ag<+> is 1.25*10<-5>M.

The invention discloses a method for detecting aromatic amine in cigarette mainstream smoke by using a gas chromatography-tandem mass spectrometry. The method is characterized by comprising the following steps of: catching aromatic amine compounds in a particulate matter in the cigarette mainstream smoke by using a Cambridge filter; extracting by using hydrochloric acid solution, washing by usingdichloromethane, reducing by using sodium hydroxide and then extracting by using normal hexane, and performing derivatization by using pentafluoropropionic anhydride and trimethylamine hydrochloride;and concentrating and detecting by using the gas chromatography-tandem mass spectrometer (GC-MS/MS) so as to measure the content of the main aromatic amine compounds in the cigarette mainstream smoke. Compared with the conventional method for analyzing the aromatic amine in the cigarette mainstream smoke, the analysis and measurement method has the advantage of simplifying the pretreatment of a sample along with higher sensitivity, high experimental repetitiveness and recovery rate and applicability to analysis of a large batch of samples.

The invention provides a method for synthesizing quaternary ammonium salt ionic liquid by microwave radiation heating, which comprises the following steps: mixing tertiary amine compounds (N,N-dimethylethanolamine, trimethylamine or triethanolamine) and halohydrocarbon compounds (allyl chloride, n-butyl chloride, n-butyl bromide, octadecyl chloride) with a molar ratio of 1:1.05-1:2 under a microwave radiation heating condition, putting the mixture into a microwave reactor to perform a microwave reaction with an adjusted microwave power of 100 W-400 W, a heating temperature of 30 DEG C-80 DEG C, and reaction time of 1 min-15 min so as to obtain a crude product, removing residual halohydrocarbon compounds in the crude product to obtain quaternary ammonium salt ionic liquid with halogens as anions; the halohydrocarbon compounds are chlorinated hydrocarbon compounds or brominated hydrocarbon compounds. The preparation method of the invention is simple, does not require the addition of any solvent except reaction raw materials, and can prepare high-purity quaternary ammonium salt ionic liquid simply, efficiently, rapidly, and economically.

The invention relates to a catalytic light-emitting sensitive material used for monitoring benzene and trimethylamine. The catalytic light-emitting sensitive material is nano powder material which consists of Ag atom doped Y2O3, Fe2O3 and ZrO2; the mass percent ranges of the components are as follows: Ag accounts for 5-15%; Y2O3 accounts for 15-25%; Fe2O3 accounts for 40-50%; ZrO2 accounts for 20-30%. A preparation method of the catalytic light-emitting sensitive material comprises the following steps: co-dissolving yttrium salt, ferric salt and zircon salt in a citric acid aqueous solution, adjusting pH value by using ammonia water in a stirring state, standing and aging, then drying and fully grinding, roasting in a chamber electric furnace, and obtaining Y2O3, Fe2O3 and ZrO2 powder material; dissolving an appropriate amount of silver nitrate and maltose in water, adding the powder material which is dispersed by ultrasonic wave into the water by continuously stirring, drying, heating and reducing, cooling, grinding and obtaining Ag atom doped Y2O3, Fe2O3 and ZrO2 nano powder. A benzene-trimethylamine catalytic light-emitting sensor, which is manufactured by using the catalytic light-emitting sensitive material, is wide in linear range, good in selectivity and high in sensitivity, and is capable of monitoring benzene and trimethylamine in the air on line without influence of coexistence substance.

The invention discloses a method for preparing betaine hydrochloride. The method comprises the following steps of: performing a quaterisation reaction on trimethylamine and chloroactic acid under the action of sodium iodide serving as a nucleophilic substitution catalytic; adding calcium oxide or calcium hydroxide; heating for discharging trimethylamine completely; acidifying with sulfuric acid to obtain a calcium sulfate-betaine hydrochloride solution; and filtering a reaction liquid, concentrating and crystallizing to obtain the betaine hydrochloride. In the method, an efficient catalyst is adopted, so that the reaction is rapid and complete; meanwhile, expensive alkalis and hydrochloric acid are not required, and only cheap calcium oxide and sulfuric acid are required; and meanwhile, no side reaction is performed, the yield is greatly increased, and the yield of the betaine hydrochloride is over 99 percent counted by chloroacetic acid, so that the cost of the method is over 20 percent lower than that of the conventional process; and the preparation period is short, the reaction conditions are mild, a product is separated easily and sufficiently, three wastes are not generated, and raw materials and a solvent can be used circularly, so that the method has higher economic efficiency and environment friendliness.

A phosphonic choline containing hydroxy is prepared through adding trimethylamine to hydroxy-contained phosphohetrocyclo pentane and anhydrous acetonitrile, sealing, reacting at 40-90 deg.C for 24-72 hr, and purifying. A biologic material containing phosphonic choline is prepared through adding diisocyanate, organic solvent, organotin as catalyst and biological film to container protected by nitrogen gas, reacting at 25-100 deg.C for 1-5 hr, and washing with organic solvent. Said biological material features high mechanical performance and high anticoagulating function.

The invention discloses a deodorizing material of a refrigerator and a preparing method of the deodorizing material. Manganese sulfate, potassium permanganate, a copper-bearing precursor and a magnesium-bearing precursor are configured into a solution, after a mixing reaction is carried out, a molecular sieve is added for dipping, the molecular sieve is dried and roasted after being dipped, active carbon and the roasted molecular sieve are formed together in an extruding mode, and the deodorizing material of the refrigerator is prepared. The deodorizing material of the refrigerator has a good effect of removing methyl mercaptan, ethyl mercaptan, trimethylamine, ammonia and hydrogen sulfide and is combined with the active carbon so that the peculiar smells in the refrigerator can be removed through chemical adsorption and physical adsorption, and the defects of chemical adsorption and the defects of physical adsorption compensate for each other.

The invention discloses a fishy flavor agent for a feed and a preparation method of the fishy flavor agent. The fishy flavor agent contains the following perfume materials in percentage by weight: 0.5-2% of glycine betaine, 1-3% of trimethylamine, 0.1-2% of 2-methyl-3-sulfydrylfuran, 0.1-1% of pyrrolidine, 0.1-1% of piperidine, 0.1-2% of phenylethylamine, 0.01-1% of 2-acetylpyridine, 0.1-1% of furanone, 1-3% of ethyl maltol, 1-3% of 2-acetylpyrazine, 1-3% of 2,3,5-trimethylpyrazine, 0.01-2% of 3-methylthiopropanal, 30-70% of fishy smell reactants and 10-60% of glycerol triacetate. The fishy flavor agent is prepared by carrying out enzymolysis on animal wastes, then adding reducing sugars to carry out Maillard reaction, and then, adding artificial synthetic essence to blend. The fishy flavor agent has the advantages that the animal wastes are reasonably utilized, the preparation process is simple, and the product is strong in fragrance, stable and easy to store.

The invention discloses a preparation technique of medium/high-viscosity dimethyl silicone oil, which comprises the following steps: swelling chloromethylated polystyrene balls in a trimethylamine water solution, and adding perfluoro tertiary amine; supporting potassium hydroxide to obtain a composite catalyst, and adding octamethylcyclotetrasiloxane (D4) and hexamethyl disiloxane (MM) into the reaction kettle; and after the reaction finishes, filtering to recover the catalyst, extracting under reduced pressure and recovering the low-boiling-point substances, thereby obtaining the methyl silicone oil product.

The invention relates to a method for determining the content of trimethylamine in egg yolk by headspace gas chromatography. The determination method is as follows: potassium hydroxide is used as a catalyst, added to the egg yolk liquid, ultrasonically, and under airtight conditions, trimethylamine is hydrolyzed and completely released from the egg yolk tissue; then trimethylamine hydrochloride is used as a standard solution, and the top Blank injection, gas chromatographic analysis. Calculate the content of trimethylamine in the sample according to the standard curve of standard substance concentration and peak area. The invention is superior to common chemical analysis methods, and has the characteristics of short analysis time, simple operation and high accuracy.

The invention discloses a method for preparing a mineral inhibitor for barite, which comprises the steps of: putting epoxy chloropropane and trimethylamine into a flat bottom flask according to the molar ratio of the epoxy chloropropane to the trimethylamine being 1-2:2-6; putting the flat bottom flask into an ice bath; closely stirring the mixture to react for 2 to 3h; standing and layering the obtained product, then taking a supernatant liquid as an intermediate product for standby; putting starch into the flat bottom flask; adding the intermediate product into the starch, taking HCl solution as a catalyst, and adding Na2SO4 which accounts for 0.1 to 0.2 percent of the mass of the total system; putting the mixture in a water bath with a temperature of between 70 and 85 DEG C, and heating the mixture to react for 3 to 4h; and then drying to obtain a powdery substance, namely the inhibitor. The inhibitor can effectively inhibit the barite in fluorite ore concentrate, can improve the grade of the fluorite ore concentrate, and has simple flow, small medicament dosage and low energy consumption.

A heparan sulfated derivative is prepared from heparan sulfated by sulphating. A preparation method comprises: swelling heparan sulfated by anhydrous dimethyl formamide, adding a sulfur trioxide-trimethylamine complex, heating for esterification, dissolving, dialyzing, freeze-drying precipitation components of the reactant by distilled water, then dissolving by sodium chloride solution, precipitating by ethanol, centrifuging, removing a supernatant, drying, and then obtaining sulphated heparan sulfated. The heparan sulfated derivative can inhibit activities of tumor cells and umbilical vein endothelial cell proliferation.

The invention relates to a dual-cation bactericide, a preparation method and application thereof. The dual-cation bactericide has the following structural formula, wherein R is saturated alkane of which the C number is 12 to 18. The method comprises the following steps of: adding 1,000 to 1,400 parts of water and 190 to 295 parts of alkyl methyl secondary amine into a reaction kettle, heating to the temperature of between 50 and 55 DEG C, adding 90 to 105 parts of epoxy chloropropane, keeping the temperature of between 60 and 65 DEG C for 3 to 6 hours, cooling to the temperature of between 40 and 45 DEG C, adding 120 to 136 parts of hydrochloric acid and 60 to 67 parts of trimethylamine, heating to the temperature of between 60 and 65 DEG C, keeping the temperature for 2 to 5 hours, cooling to the temperature of between 40 and 45 DEG C, adding 123 to 131 parts of benzyl chloride, heating to the temperature of between 70 and 85 DEG C, keeping the temperature for 4 to 8 hours, and thus obtaining the dual-cation quaternary ammonium salt bactericide, wherein each raw material in the reaction is proportioned in part by weight. The dual-cation bactericide has a better bactericidal effect, is low in cost, and has economical efficiency and feasibility; and the raw materials are readily available.

The invention discloses a hydrolysis resistant Si-C-Si type cation organosilicon surfactant. The hydrolysis resistant Si-C-Si type cation organosilicon surfactant is prepared by performing reaction on the chloropropy carbosilane, N-methylimidazole, N-methylpyrrolidine, N, N-dimethylethanolamine, trimethylamine, triethylamine or pyridine. The prepared surfactant has good surface activity and a certain germicidal activity and can be used in the fields such as pesticide adjuvants, drug sustained release, functional nano-materials and textile processing aids.

The invention discloses a preparation method of an anion exchange chromatography stationary phase using highly-crosslinked glycidyl methacrylate-divinyl benzene microspheres as a matrix. The preparation method includes: adopting a dispersion polymerization method to prepare monodispersed linear polystyrene seed microspheres; adopting a two-step seed swelling method to prepare highly-crosslinked glycidyl methacrylate-divinyl benzene copolymer microspheres; using methylamine, dimethylamine, trimethylamine, diethylamine, triethylamine and 1, 4-butane dioldiglycidyl ether as reaction raw materials to modify the highly-crosslinked glycidyl methacrylate-divinyl benzene copolymer microspheres to prepare the anion exchange chromatography stationary phase.

The invention relates to a highly selective sensitive material for trimethylamine and hydrogen sulfide, which is characterized in that the material is the composite powder material composed of Dy2O3,MoO3 and ZrO2. The preparation method comprises the steps of uniformly mixing acetic acid aqueous solution of dysprosium salt and isocitric acid aqueous solution of zircon salt; directly adding ammonium molybdate crystals into the mixture; adding carboxymethylcellulose to form a thick colloidal solution; and aging, drying, calcinating at two stages and naturally cooling to acquire the composite powder material composed of Dy2O3, MoO3 and ZrO2. A gas sensor manufactured by using the sensitive material provided by the invention can measure the trace trimethylamine and hydrogen sulfide in the airwith high sensitivity on the scene without being interfered by other common coexisting molecules.

The invention discloses a method for preparing high-content alpha-lauryl betaine by solvent-free quaternization, which belongs to the technical filed of organic synthesis. Particularly, a hot-press condition is implemented for quaternization of trimethylamine and alpha-halogenated carboxylic acid, and the trimethylamine which is one of reaction materials is liquefied under the hot-press condition and is simultaneously used as a reaction medium, so that the problem of difficulty in enhancing the reaction material concentration, mass and heat transfer and the like is solved skillfully; and an additional solvent is avoided being used, so that quaternization is undergone under the solvent-free condition to synthesize alpha-lauryl betaine, particularly alpha-long-chain lauryl betaine, serving as an amphoteric surfactant. The technology disclosed by the invention can be implemented under the solvent-free condition, so that the hydrolytic side reaction of alpha-halogenated carboxylic acid in an aqueous solution is avoided, the yield of alpha-lauryl betaine is effectively increased, or the product pollution and the environmental pollution caused by the use of an organic solvent are avoided, and the product purity is remarkably increased; and the method has a simple process, excessive raw material, namely trimethylamine, is recycled after being evaporated and recovered, an end product, namely alpha-lauryl betaine is a high-content solid-state product, and a preparation process is emission-free.

The invention discloses a preparation method of a thickness controllable WO3 nano sheet for a trimethylamine gas sensor, and belongs to the field of gas sensors. The thickness of the WO3 nano sheet can be regulated from about 10 nm to about 5nm. According to the invention, a method of adopting dual surfactants is carried out, and the thickness of the WO3 nano sheet can be controlled through the regulation of preparation conditions such as the initial reaction temperature, the usage amounts of sodium oleate and sodium caprylate, the concentration and usage amount of nitric acid and sodium tungstate, the temperature preservation time, the stirring time and the like. The thickness controllable WO3 nano sheet prepared by the method is used as a coating material of a gas sensor and achieves a good effect in detecting trimethylamine. When the thickness of the nano sheet is 5 nm, the response to trimethylamine (TEA) is good at a temperature of 25 DEG C, and when the TEA content is 250 ppm, the response value is 8.2, and the selectivity is good.