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Application of astragalus polysaccharide on drosophila melanogaster in oxidation resistance and aging resistance

An astragalus polysaccharide, anti-aging technology, applied in medical preparations containing active ingredients, anti-toxic agents, organic active ingredients, etc.

Inactive Publication Date: 2019-12-20
长治学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There is no report on the effect of astragalus polysaccharides on the lifespan and anti-oxidation of Drosophila

Method used

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  • Application of astragalus polysaccharide on drosophila melanogaster in oxidation resistance and aging resistance
  • Application of astragalus polysaccharide on drosophila melanogaster in oxidation resistance and aging resistance
  • Application of astragalus polysaccharide on drosophila melanogaster in oxidation resistance and aging resistance

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Experimental program
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Effect test

Embodiment

[0022] The wild-type Drosophila melanogaster was selected, and the male adults weighed (0.531±0.049) mg, and the female adults weighed (0.714±0.052) mg, both provided by the Genetics Laboratory of the Department of Biological Science and Technology, Changzhi University; astragalus polysaccharide ( Astragalus Polysaccharide), purchased from Beijing Suolaibao Technology Co., Ltd., with a purity of UV ≥ 90%.

[0023] Superoxide dismutase (SOD) activity, total antioxidant capacity (T-AOC) activity and malondialdehyde (MDA) content were measured and calculated using corresponding kits, which were purchased from Beijing Suo Laibao Technology Co., Ltd., and the numbers were respectively for A001-3, A1005 and A003-1.

[0024] BSA 124S-CW electronic balance, Sartorius Scientific Instruments (Beijing) Co., Ltd.; SMZ-B2 continuous zoom stereo microscope, Chongqing Aopu Optoelectronics Technology Co., Ltd.; TGL-20M high-speed refrigerated centrifuge, Changsha Xiangyi centrifuge instrument...

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Abstract

The invention discloses application of astragalus polysaccharide on drosophila melanogaster in oxidation resistance and aging resistance, improvement of oxidation resistance of the drosophila melanogaster, enhancement of constitution of the drosophila melanogaster and improvement of improvement aging resistance of the drosophila melanogaster. By feeding of drosophila melanogaster culture media atdifferent concentration, the change of the astragalus polysaccharide for life and antioxidant enzyme activity of the drosophila melanogaster is studied in order to provide certain experimental basis for development of astragalus polysaccharide. When the concentration of the astragalus polysaccharide is 1.0 [mu] g / mL, the average life, half death time and the highest life of male and female drosophila melanogaster can be prolonged, the inverse-gravity crawling capacity of the drosophila melanogaster can be enhanced, the SOD enzyme activity and T-AOC content of organisms are the highest, and theMDA content is the lowest.

Description

technical field [0001] The invention relates to the technical field of astragalus polysaccharides, in particular to an application of astragalus polysaccharides in anti-oxidation and anti-aging of fruit flies. Background technique [0002] Aging is one of the main causes of many chronic diseases. In recent years, the prevention of aging has gradually become the focus of people's attention, and health food and medicines to improve the body's immunity have also emerged as the times require. A large number of studies have proved that traditional Chinese medicine polysaccharides, especially tonic polysaccharides, can improve the quality of the body's immune organs, enhance the immune function of animals, and have the advantages of safety, non-toxicity, and no residue. They are an excellent class of biological response modifiers. [0003] The traditional Chinese medicine Radix Astragali (Radix Astragali), also known as Beiqi and Mianqi, is a perennial herb of the leguminous fami...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61P39/06
CPCA61K31/715A61P39/06
Inventor 秦永燕姚沁涛
Owner 长治学院
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