Liquid phase chip workstation

Abstract

The invention relates to the technical field of biological analysis and detection, in particular to a liquid phase chip workstation, and mainly solves the technical problem in the prior art of defectsin detection efficiency. The technical point thereof is that the workstation comprises the following parts of a liquid phase chip that comprises polymeric microspheres, identification molecules and probe molecules; a reaction module comprising an excitation light source, a microfluidic channel and an optical board, wherein the excitation light source is refracted into the microfluidic channel; and an analysis module comprising computer hardware and image analysis software and used to receive and process the data from the reaction module. The existence of the reaction board can move the microspheres through the wide microfluidic channel system continuously, evenly and stably in a plurality of rows and at an even speed such that the detection speed and efficiency are obviously improved, andthousands of microspheres can be detected every second, thereby simplifying the steps requiring manual setting and significantly improving the detection efficiency.

Description

technical field [0001] The invention relates to the technical field of biological analysis and detection, in particular to a liquid phase chip workstation. Background technique [0002] With the rapid development of analytical and diagnostic technology, the liquid phase chip developed in the mid-1990s, known as the post-gene era, is a new type of protein research platform, which combines flow cytometry technology with traditional chip technology. A new platform for protein research. The system organically integrates colored microspheres, modern immune technology, laser technology, applied fluidics, the latest high-speed digital signal processor and computer algorithms, resulting in extremely high detection specificity and sensitivity. It can be used for clinical disease diagnosis, such as detection of cytokines, allergens and autoimmune reactions, HLA typing, SNP detection, quantitative detection of tumor-specific antigens, quantitative detection of multiple microorganisms,...

AI Technical Summary

Problems solved by technology

[0004] Due to the limitations of the fluorescence spectral bandwidth and the dynamic range of signal intensity detection, when the total number of codes required is large, the number of groups used in all levels of codes is usually small, resulting in a greater dependence on the instrument’s detection performance indicators. The optical system is complex, bulky, and costly, which also limits its detection speed, so a liquid phase chip workstation is needed to solve the above defects

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