Method for decolorizing extract of Clinopodium polycephalum

A technology of cutting off blood flow and extracting liquid, which is applied in the field of traditional Chinese medicine extraction and decolorization, can solve the problems of large amount of hydrogen peroxide, difficult filtration, cumbersome process, etc., and achieve the effect of less loss of active ingredients, low price and simple operation

Inactive Publication Date: 2020-02-14
LIUZHOU LIANGMIANZHEN
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Activated carbon decolorization, resin decolorization, H 2 o 2 Decolorization is a decolorization method with a wide range of applications, but it has many disadvantages. For example, activated carbon will cause difficulty in filtration, and the residue left behind will also have a great impact on quality; the price of resin is relatively expensive, and the process is cumbersome; the amount of hydrogen peroxide is large
Therefore, these decolorization methods are not suitable for the decolorization of Chinese medicine extracts, especially for the decolorization of Chinese medicine Duanxueliu extract

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for decolorizing extract of Clinopodium polycephalum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Duanxueliu extraction process: the Duanxueliu medicinal materials are removed from sediment, dried in the sun, chopped in sections, and then placed in extraction equipment. Add 8 times the mass of ethanol-water solution with a volume fraction of 75% to the cut off blood medicinal material, extract under constant temperature reflux at 90°C for 2 hours, filter, collect the filtrate, repeat the above process, extract twice, and combine the filtrates to obtain the extract. Concentrate the extract under reduced pressure in a water bath at 60°C to obtain a 1:1 off-blood flow extract, and control the ethanol content of the potion between 30% and 40%.

[0029] Decolorization process of cut off blood flow extract: Preheat the 1:1 cut off blood flow extract to a constant temperature of 30°C, then add 3.0% calcium hydroxide decolorizer (the amount of calcium hydroxide needs to be added based on the mass of the cut off blood flow extract ), stirring and decolorizing for 30min. Aft...

Embodiment 2

[0039] Duanxueliu extraction process: the Duanxueliu medicinal materials are removed from sediment, dried in the sun, chopped in sections, and then placed in extraction equipment. Add 7 times the mass of ethanol-water solution with a volume fraction of 60% to the cut off blood medicinal material, reflux at 90°C for 2 hours, filter, collect the filtrate, repeat the above process, extract twice, and combine the filtrates to obtain the extract. Concentrate the extract under reduced pressure in a water bath at 65°C to obtain a 1:1 off-blood flow extract, and control the ethanol content of the potion between 20% and 30%.

[0040] Decolorization process of cutoff blood extract: preheat the 1:1 cutoff extract to a constant temperature of 40°C, then add 1.0% calcium hydroxide decolorizer (according to the mass of decolorized cutoff extract, the amount of calcium hydroxide needs to be added ), stirring and decolorizing for 20min. After the decolorization is completed, centrifugation a...

Embodiment 3

[0043] Duanxueliu extraction process: the Duanxueliu medicinal materials are removed from sediment, dried in the sun, chopped in sections, and then placed in extraction equipment. Add 8 times the mass of ethanol-water solution with a volume fraction of 75% to the cut off blood medicinal material, extract at a constant temperature at 95°C for 2 hours, filter, collect the filtrate, repeat the above process, extract twice, and combine the filtrates to obtain the extract. Concentrate the extract under reduced pressure in a water bath at 55°C to obtain a 1:1 off-blood flow extract, and control the ethanol content of the potion between 40% and 50%.

[0044] Decolorization process of cutoff blood extract: Preheat the 1:1 cutoff extract to a constant temperature of 30°C, then add 2.0% calcium hydroxide decolorizer (according to the mass of decolorized cutoff extract, the amount of calcium hydroxide needs to be added ), stirring and decolorizing for 30min. After the decolorization is ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for decolorizing an extract of Clinopodium polycephalum, and belongs to the technical field of extraction and decolorization of traditional Chinese medicine. The method comprises the steps: adding calcium hydroxide to the extract of Clinopodium polycephalum, performing heating and stirring for decolorizing treatment, performing centrifugation and filtration, collecting the filtrate, and then adjusting the pH value of the filtrate so as to stabilize the pH value at 4-7.5. When the method is compared with an existing decolorization method of the extract of Clinopodium polycephalum, calcium hydroxide is adopted as a decolorization agent for the extract of Clinopodium polycephalum, the decolorization agent has low cost and simple operation, and the decolorizedliquid has the advantages of light color and high content of active components.

Description

technical field [0001] The invention belongs to the technical field of extraction and decolorization of traditional Chinese medicines, and in particular relates to a method for decolorization of blood-cutting extract. Background technique [0002] Duanxueliu was originally an herbal medicine excavated from folk use in Anhui Province. The part used as medicine is the dry aboveground part of the Lamiaceae plant Lanternaria or Campanula, harvested before flowering in summer, removed the sediment, and dried in the sun. [0003] Current pharmacological studies have shown that the water extract and alcohol extract of Duanxueliu contain a large number of phytochemical components, mainly including saponins, flavonoids, amino acids, polysaccharides, phenolic substances and volatile oils. Studies have proved that off blood flow has hemostasis, anti-inflammatory and antibacterial, contraction of blood vessels, contraction of the uterus, regulation of endocrine, suppression of immune f...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & AuthorityApplications(China)
IPC IPC(8): A61K36/53
CPCA61K36/53A61K2236/333A61K2236/51A61K2236/53
Inventor黄光伟刘文佳韦宝韩唐红艳黄静梁雪松劳洁
OwnerLIUZHOU LIANGMIANZHEN