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Wound healing-promoting medical dressing capable of inhibiting scar generation, and preparation method thereof

A wound healing and medical technology, applied in medical science, bandages, etc., can solve the problems of skin damage, difficult to heal, local pain, etc., to achieve the effect of promoting wound recovery, accurate curative effect, and promoting cell growth

Pending Publication Date: 2020-05-05
THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

From the perspective of repair effect, surgical resection and laser treatment have a high recurrence rate, and some may cause skin damage or local pain; traditional drug treatment can control the development of the disease and relieve symptoms, but it is not easy to recover

Method used

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  • Wound healing-promoting medical dressing capable of inhibiting scar generation, and preparation method thereof
  • Wound healing-promoting medical dressing capable of inhibiting scar generation, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A wound-healing medical dressing capable of inhibiting scar production, comprising the following raw material components in percentage by weight: human-like collagen 2%, vascular endothelial growth factor 0.9%, active polypeptide composition (acetyl tetrapeptide-2 and palmitoyl The weight ratio of tripeptide-1 is 1:1 composition) 1.5%, carboxymethyl chitosan 5%, hydroxypropyl methylcellulose 14%, and the balance is deionized water.

[0024] Among them, human-like collagen was purchased from Novus Biologicals Company of the United States; vascular endothelial growth factor was purchased from Sigma Company of the United States; acetyl tetrapeptide-2 and palmitoyl tripeptide-1 were purchased from Zhejiang Paitide Biological Co., Ltd.

[0025] The preparation method of the medical dressing for promoting wound healing comprises the following steps: adding carboxymethyl chitosan to an appropriate amount of deionized water, stirring evenly in a vacuum, and obtaining carboxymeth...

Embodiment 2

[0027]A wound-healing medical dressing capable of inhibiting scar production, comprising the following raw material components in percentage by weight: human-like collagen 1%, vascular endothelial growth factor 0.6%, active polypeptide composition (acetyl tetrapeptide-2 and palmitoyl The weight ratio of tripeptide-1 is 1:1 composition) 2%, carboxymethyl chitosan 4%, hydroxypropyl methylcellulose 12%, and the balance is deionized water.

[0028] The preparation method of the medical dressing for promoting wound healing is the same as in Example 1.

Embodiment 3

[0030] A wound-healing medical dressing capable of inhibiting scar production, comprising the following raw material components in percentage by weight: human-like collagen 1.5%, vascular endothelial growth factor 0.7%, active polypeptide composition (acetyl tetrapeptide-2 and palmitoyl The weight ratio of tripeptide-1 is 1:1 composition) 1.5%, carboxymethyl chitosan 3.5%, hydroxypropyl methylcellulose 13%, and the balance is deionized water.

[0031] The preparation method of the medical dressing for promoting wound healing is the same as in Example 1.

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Abstract

The invention belongs to the field of medical dressings, and in particular relates to a wound healing-promoting medical dressing capable of inhibiting scar generation, and a preparation method thereof. The medical dressing combines human-like collagen, a vascular endothelial growth factor, an active polypeptide composition and other active ingredients, wherein the human-like collagen and the vascular endothelial growth factor can promote cell growth and regulate a wound repair process, and the active polypeptide composition has promoting effects on the repair of epidermal skin and texture, wound recovery, and tissue renewal and reconstruction, and effectively inhibits scar generation. The cooperative use of the ingredients can promote the orderly growth of tissues and speed up the wound healing process, and at the same time, the ingredients have synergistic effects in inhibiting scar generation, so that no recurrence exists after treatment is completed.

Description

technical field [0001] The invention belongs to the field of medical dressings, and in particular relates to a wound healing-promoting medical dressing capable of inhibiting scar generation and a preparation method thereof. Background technique [0002] The skin is the barrier between the human body and the external environment, protecting various tissues and organs in the body from external physical, mechanical, chemical and pathogenic microorganisms. When the skin is damaged, if it cannot heal in time, the surface of the wound should be covered with dressing in time. As a covering for wounds, medical dressings can replace damaged skin to act as a temporary barrier during wound healing, avoid or control wound infection, and provide an environment conducive to wound healing. With the aging population and the increase of chronic ulcerative wounds, the market value of medical dressings is also becoming more and more important. According to the materials used, medical dressin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0023A61L26/0033A61L26/0047A61L26/0066A61L26/008A61L2300/252A61L2300/412A61L2300/414C08L5/08C08L1/284C08L89/00
Inventor 李力群张宏宇林明
Owner THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV
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