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Biological artificial liver purification circulation unit and artificial liver support system

A purification cycle and artificial liver technology, applied in dialysis systems, suction devices, etc., can solve the problems of lack of liver synthesis and biotransformation capabilities, and achieve the effects of high density, reduced dosage requirements, and large biological surface area

Active Publication Date: 2020-06-09
THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV
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  • Claims
  • Application Information

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Problems solved by technology

It can temporarily compensate for the detoxification effect of the liver, but the system only performs blood purification by non-biological means, lacking the replacement of liver synthesis and biotransformation capacity

Method used

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  • Biological artificial liver purification circulation unit and artificial liver support system
  • Biological artificial liver purification circulation unit and artificial liver support system
  • Biological artificial liver purification circulation unit and artificial liver support system

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Embodiment Construction

[0050] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0051] The embodiment of this application provides a biological artificial liver purification circulation unit and artificial liver support system. The embodiment of this application combines non-biological blood purification means such as adsorption with a bioreactor, and adds biological conversion and synthesis functions on the basis of detoxification. Give full play to the purification advantages of various means.

[0052] see figure 1 , the bioartificial ...

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Abstract

The embodiment of the invention discloses a biological artificial liver purification circulation unit and an artificial liver support system. According to the embodiment of the invention, non-biological blood purification means such as blood filtration, plasma adsorption and the like are combined with a bioreactor, biological conversion and synthesis functions is added on the basis of detoxification, and purification advantages of various means are fully exerted. The biological artificial liver purification circulation unit provided by the embodiment of the invention comprises a plasma storagebag, a pipeline warmer, a plasma circulating pump, a high-flux filter, a neutral resin adsorber, a dissolved oxygen-PH monitor and a bioreactor which are sequentially connected through a circulationpipeline.

Description

technical field [0001] The invention relates to a medical device, in particular to a bioartificial liver purification circulation unit and an artificial liver support system. Background technique [0002] The blood purification technology for artificial liver replacement therapy is developing rapidly. At present, the domestic treatment is dominated by component plasma exchange, while the research hotspot abroad is the albumin dialysis adsorption system. The representative method is the molecular adsorption recirculation system (MARS). The basic principle of this type of method is to use albumin solution as the dialysate in the protein dialysis cycle, so that the protein-bound toxins and other types of toxin molecules in the patient's blood are transferred to the albumin solution through the MARS dialysis membrane, so that the blood can be obtained. Purification. At the same time, the protein solution purification and regeneration cycle purifies the polluted albumin solution ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/18
CPCA61M1/16A61M1/1676
Inventor 蒋永芳周宁周艳文龚国忠田沂彭锋
Owner THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV
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