A method for studying genetic homozygosity based on sd rats

A technology of homozygosity and rats, applied in the field of SD rat genetics, can solve the problems of not being able to study the homozygosity of SD rats well, and the research results are not intuitive and accurate enough, so as to achieve a thorough understanding and increase the effect of accuracy

Active Publication Date: 2022-04-15
湖北贝恩特生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] Aiming at the deficiencies in the prior art, the present invention provides a method based on the study of SD rat genetic homozygosity, which solves the problem that the research results of genetic homozygosity are not intuitive and accurate enough and cannot be well understood when the SD rat is studied genetically. Problems of Studying the Related Conditions of Homozygosity in SD Rats

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  • A method for studying genetic homozygosity based on sd rats
  • A method for studying genetic homozygosity based on sd rats

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Experimental program
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Embodiment 1

[0029] A method for studying genetic homozygosity based on SD rats, comprising the following steps:

[0030] S1. Preparation: Prepare 8 SD rats with healthy limbs, healthy body, 320 g body weight and the same coat color. The SD rats are all 60 days old, with half of the female SD rats and half of the male SD rats, and Half of the 8 SD rats were wild SD rats, and the other half were artificially raised SD rats, and then the 8 SD rats were divided into four groups, the two groups were artificially raised SD rats and wild SD rats, The four groups of SD rats were wild female SD rats and wild male SD rats, artificially raised female SD rats and artificially raised male SD rats, wild female SD rats and artificially raised male SD rats, and wild male SD rats. Rats and artificially raised female SD rats;

[0031] S2, first-generation breeding: place the four groups of SD rats in step S1 in four breeding pens respectively, feed the SD rats in the artificial feeding group every day and...

Embodiment 2

[0045] A method for studying genetic homozygosity based on SD rats, comprising the following steps:

[0046] S1. Preparation: Prepare 8 SD rats with healthy limbs, healthy body, 350 g body weight and the same coat color. The SD rats are all 70 days old, and half of them are female SD rats and half of male SD rats. Half of the 8 SD rats were wild SD rats, and the other half were artificially raised SD rats, and then the 8 SD rats were divided into four groups, the two groups were artificially raised SD rats and wild SD rats, The four groups of SD rats were wild female SD rats and wild male SD rats, artificially raised female SD rats and artificially raised male SD rats, wild female SD rats and artificially raised male SD rats, and wild male SD rats. Rats and artificially raised female SD rats;

[0047] S2, first-generation breeding: place the four groups of SD rats in step S1 in four breeding pens respectively, feed the SD rats in the artificial feeding group every day and art...

Embodiment 3

[0061] A method for studying genetic homozygosity based on SD rats, comprising the following steps:

[0062] S1. Preparation: prepare 8 SD rats with healthy limbs, healthy body, 330 g body weight, and the same coat color. The SD rats are all 65 days old, with half of the female SD rats and half of the male SD rats, and Half of the 8 SD rats were wild SD rats, and the other half were artificially raised SD rats, and then the 8 SD rats were divided into four groups, the two groups were artificially raised SD rats and wild SD rats, The four groups of SD rats were wild female SD rats and wild male SD rats, artificially raised female SD rats and artificially raised male SD rats, wild female SD rats and artificially raised male SD rats, and wild male SD rats. Rats and artificially raised female SD rats;

[0063] S2, first-generation breeding: place the four groups of SD rats in step S1 in four breeding pens respectively, feed the SD rats in the artificial feeding group every day an...

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Abstract

The invention discloses a research method based on the genetic homozygosity of SD rats, including preparatory work, first-generation breeding, first-generation mating, first-generation cultivation, second-generation birth, second-generation mating, and third-generation birth. The four groups of SD rats are wild female SD rats. Rats and wild male SD rats, artificially raised female SD rats and artificially raised male SD rats, wild female SD rats and artificially raised male SD rats, wild male SD rats and artificially raised female SD rats. The present invention relates to the field of SD rat genetic technology. Based on the SD rat genetic homozygosity research method, wild female SD rats and artificially raised male SD rats, wild male SD rats and artificially raised female SD rats can The wild SD rats and artificially raised SD rats were compared and mated. Among the offspring produced in this way, the staff can more intuitively observe the genetic homozygosity of different types of SD rats and increase the accuracy of the experiment.

Description

technical field [0001] The invention relates to the technical field of SD rat genetics, in particular to a research method based on SD rat genetic homozygosity. Background technique [0002] SD rats are a strain of rats, belonging to Animal Kingdom, Chordate Phylum, Vertebrate Subphylum, Mammalia, Rodentia, Muridae, Rats, and Rats. SD rats have a long and narrow head and a long tail. Its length is close to its body length, it has more litters, its growth and development are faster than Wistar rats, its temperament is slightly fiercer than Wistar rats, and its adaptability and disease resistance are stronger than Wistar rats, especially its resistance to respiratory diseases. Favored by animal experiments, but its price is more expensive, the current scale of breeding is not as wide as Wistar rats, but it is also a relatively important experimental rat species, and the incidence of spontaneous tumors is low. For research, SD rats need to be mated, and the offspring of SD rat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01K67/02
CPCA01K67/02
Inventor 王文杰张念王文娟杨阳唐业何咏梅
Owner 湖北贝恩特生物科技有限公司
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