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Application of Tribenzyl Glycoside in the Treatment of Skin Diseases Caused by Microcirculation Disorders

A technology for microcirculation disorders and skin diseases, which is applied in the field of skin disease drugs to achieve good curative effects and improve the symptoms of patients

Active Publication Date: 2022-08-05
HEFEI BOSIKC PHARMTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Kalbhen.D.A and others published about the anti-inflammatory effect of tribenzyl glycoside, but there is no report about the application of tribenzyl glycoside in the treatment of skin diseases caused by microcirculation disturbance

Method used

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  • Application of Tribenzyl Glycoside in the Treatment of Skin Diseases Caused by Microcirculation Disorders
  • Application of Tribenzyl Glycoside in the Treatment of Skin Diseases Caused by Microcirculation Disorders

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 3

[0017] Example 1 Clinical application of tribenzyl glycoside in the treatment of centrifugal erythema annulare

[0018] 1. Verification

[0019] 1. Test objects and groups

[0020] Eighty patients with centrifugal erythema annularis were enrolled, including 62 males and 18 females, aged 40-76 years, with an average age of 58.3±7.4 years. They were randomly divided into two groups, A and B.

[0021] Group A was set as the tribenzyl glycoside treatment group, with 32 males and 8 females, aged 40-67 years, mean age 57.0±3.5 years, disease duration 10 months-7 years, mean disease duration 4.8±0.7 years.

[0022] Group B was set as the conventional treatment group, with 30 males and 10 females, aged 51-76 years, with an average age of 64.6±5.1 years, and a disease course of 1.1 years to 10 years, with an average disease course of 5.2±1.1 years.

[0023] The course of disease and the severity of symptoms between the two groups were basically the same, and there was no significant...

Embodiment 2 3

[0052] Example 2 Clinical application of tribenzyl glycoside in the treatment of hair loss

[0053] 1. Verification

[0054] 1. Test objects and groups

[0055] 200 patients with alopecia were enrolled and randomly divided into 5 groups, numbered 1-5 respectively. There were 40 cases in each group, including 20 males and 20 females, aged 25-55 years. Thirty of 40 patients in each group had mild to moderate alopecia.

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Abstract

The invention discloses a new use of tribenzyl glycoside in the treatment of skin diseases caused by microcirculation disorders. Medicines using tribenzyl glycosides as active ingredients have good curative effect in treating skin diseases caused by microcirculation disorders, and can significantly improve the patient's condition. Symptoms provide new ideas for the prevention and treatment of skin diseases caused by microcirculation disorders.

Description

technical field [0001] The invention relates to the technical field of dermatological medicines, in particular to the application of tribenzyl glycoside in the treatment of skin diseases caused by microcirculation disorders. Background technique [0002] Microcirculation is the blood circulation in the capillaries between the blood supplying tiny arteries and tiny veins. It includes the blood supplying tiny arteries, tiny veins, tiny lymphatic capillaries, and the body fluid circulation in the body tissue pipes. The main function is to supply blood tiny arteries. In the blood, tissue cells and interstitial fluid in the intercellular space, the material exchange between the blind ends of tiny lymphatic vessels. The essence of microcirculation disorder is the lack of nutrient supply required for cell replication and the obstruction of the transport of cells' own metabolic wastes. After the local microcirculation disorder caused by the blockage of a certain number of arterial c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7034A61P17/00A61P9/14A61P17/14
CPCA61K31/7034A61P17/00A61P9/14A61P17/14
Inventor 郭芓祺郭辉吴友灵盛荣
Owner HEFEI BOSIKC PHARMTECH CO LTD