Preparation, product and application of biodegradable 3D printing gel

A 3D printing and biodegradation technology, which is applied in the preparation and application of 3D printing materials, can solve the problems of poor biodegradability, slow degradation, time-consuming and energy-consuming, etc., and achieve good biocompatibility, not easy to plastic deformation, The effect of enhancing malleability

Active Publication Date: 2021-01-08
CHINA AGRI UNIV
View PDF7 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the biomaterials used in 3D printing have the following problems: synthetic materials with high mechanical strength have poor biodegradability, and some biomaterials from natural sources cannot meet the requirements of printing and mechanical properties during application
Synthetic materials such as polyurethane are not only time-consuming and energy-consuming to synthesize, but also degrade slowly, which hinders their wide application. Bio-derived hydrogels based on starch, alginate, etc. are cheap and degrade quickly, but in high-load conditions that do not provide adequate mechanical integrity

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation, product and application of biodegradable 3D printing gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A method for preparing a 3D printing gel with adjustable mechanical properties and biodegradability, the steps are as follows:

[0031] (1) Dissolve 1g of citric acid and 5g of glycerin in 8g of deionized water, and heat to 60°C to form a solution;

[0032] (2) Heat 7 g of glucose syrup to 60° C. to reduce its viscosity, and mix it with the solution obtained in (1).

[0033] (3) After the solution prepared in step (2) is cooled to room temperature, add 4 g of gelatin powder and mix well.

[0034] Print Example 1

[0035] The mixture obtained in Example 1 was heated in an oven at 70° C. for 1 h, stirred evenly, put into a printing tube, and centrifuged at 10,000 rpm for 10 min to remove air bubbles.

[0036] Set the printing parameters as follows: printing temperature 25°C, printing height 0.5mm, extrusion rate 30mm / s, nozzle diameter 0.5mm;

[0037] After entering the printing pattern in the printer, printing is started with the hydrogel.

Embodiment 2

[0039] Adopt substantially the same preparation method as in Example 1, except that 4 g of glycerin is dissolved in 8 g of deionized water in step (3).

Embodiment 3

[0041] Adopt substantially the same preparation method as in Example 1, except that 9 g of glycerol is added in step (3) and dissolved in 3 g of deionized water.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides preparation, a product and application of biodegradable 3D printing gel. The preparation method comprises the steps of preparing a solution from citric acid, glycerin and water,wherein the mass ratio of citric acid to glycerin to water is 1: (2-10): (2-10); mixing glucose syrup with the solution obtained in the step (1), wherein the mass ratio of the glucose syrup to citricacid is (5-9): 1; and (3) adding gelatin into the solution obtained in the step (2), wherein the mass ratio of the gelatin to the citric acid is (6-12): 1. According to the preparation method of the3D printing gel provided by the invention, the stable processability and processing conditions of the gel are realized by adjusting the ratio of water to glycerol, that is, the adjustment of the mechanical strength is realized; the citric acid is added, so that the pH environment of the gel can be adjusted, and meanwhile, the growth of microorganisms can be inhibited; all the selected materials are food-grade, environment-friendly and easy to degrade.

Description

technical field [0001] The invention belongs to the technical field of functional materials, and in particular relates to the preparation and application of a 3D printing material. Background technique [0002] 3D printing technology, also known as additive manufacturing, works by sequentially depositing material layer by layer to form three-dimensionally shaped objects. 3D printing technology has revealed new ways of producing parts, and the potential direction of this technology in the field of biological tissue engineering has now developed into an important tool for the production of biological constructs for regenerative purposes or as tissue models. Extrusion-based 3D printing is the most commonly used way to manufacture biological tissue models. Extrusion-type 3D printing facilities mainly include mechanical or pneumatic distribution systems, through which the nozzles (print heads) of the distribution system continuously and layer by layer deposit biomaterials onto t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C08J3/075C08L89/00C08K5/092C08K5/053C08K5/07B33Y70/10
CPCB33Y70/10C08J3/075C08J2389/00C08K5/053C08K5/07C08K5/092
Inventor 宋弋卢舒瑜马涛户昕娜胡小松
Owner CHINA AGRI UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap