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Application of plant additive of oxygen-sugar double-antibody to preparation of composition having anti-glycation effect

A kind of composition and additive technology, applied in the field of chemistry, can solve the problems such as no report on the application of bamboo leek extract

Inactive Publication Date: 2021-01-15
SUZHOU HEYAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there is no report about the application of bamboo leek extract in the preparation of anti-glycation products

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: the preparation of bamboo leek extract (dry distillation method)

[0029] Specific steps are as follows:

[0030] Choose 2-year-old light bamboo, remove the branches and leaves, remove the knots at both ends, cut into 30cm long bamboo sections, and divide into 2cm wide bamboo strips; take 100kg bamboo strips and place them in the altar, surround the altar and the bottom with charcoal, and connect it under the altar Collect the oozing juice in a container and bake it until the juice is exhausted to obtain bamboo leach juice; dilute the bamboo leek juice with water to a total solid content of 0.5% to obtain diluted bamboo leach juice; place the diluted bamboo leach juice in a centrifuge at 3500rpm After 40 min, the supernatant was taken; the supernatant was filtered through a carbon rod and then filtered with a ceramic membrane (molecular weight permeated to 80,000 Daltons) to obtain a clear and transparent bamboo leek extract A.

Embodiment 2

[0031] Embodiment 2: the preparation of bamboo leek extract (decoction method)

[0032] Specific steps are as follows:

[0033] Choose 1-year-old gray bamboo, remove branches and leaves, remove joints at both ends, cut into 30cm long bamboo sections, and cut into 2cm wide bamboo strips; take 100kg bamboo strips and add water to decoct twice, the first time use 10 times the mass of water to decoct Boil for 2 hours, decoct for 1.5 hours with 8 times the mass of water for the second time, and combine the extracts; concentrate the extracts in a vacuum film at a temperature of 90°C, a vacuum of -0.090MPa, and a flow rate of 150L / h. The total solid content of the liquid is 2%, and the concentrated extract is obtained; the concentrated extract is placed at 8000rpm and centrifuged for 20min, and the supernatant is obtained; the supernatant is filtered through a sand core with a hollow fiber membrane (the molecular weight of permeation is 12 10,000 Daltons) to filter to obtain a clear...

Embodiment 3

[0034] Embodiment 3: the soft capsule of oxyglucose double antibody

[0035] The contents of this soft capsule (150mg / 1 capsule) are as follows:

[0036] Formula: 15 mg of bamboo leek extract A obtained in Example 1, 3 mg of ceramide, 2 mg of fish oil, 3 mg of vitamin C, 0.5 mg of vitamin E, 0.5 mg of hyaluronic acid, 5 mg of beeswax, 90 mg of gelatin, and 31 mg of glycerin.

[0037] Preparation method: weigh each raw material according to the above formula and mix them evenly, and prepare ointment soft capsules according to the conventional technology in this field.

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PUM

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Abstract

The invention relates to an application of a plant additive of an oxygen-sugar double-antibody to preparation of a composition having an anti-glycation effect, and belongs to the technical field of chemical research. Research finds that a bamboo juice extract can inhibit generation of fluorescent AGEs, the inhibition rate reaches up to 53.14 + / -1.01%, and the bamboo juice extract has a good anti-glycation effect. In addition, the bamboo juice extract also has good antioxidant, whitening and moisturizing effects, and also has extremely high application prospects in preparation of antioxidant, whitening and moisturizing products.

Description

technical field [0001] The invention relates to the application of a plant additive of oxygen-glucose dual resistance in the preparation of a composition with anti-glycation effect, and belongs to the field of chemical technology. Background technique [0002] Advanced Glycation End-products (Advanced Glycation End-products, hereinafter referred to as "AGEs") refer to the process of free amino groups of macromolecular substances such as proteins, amino acids, lipids or nucleic acids and aldehyde groups of reducing sugars under non-enzymatic conditions. A group of stable end products produced after condensation, rearrangement, cleavage, and oxidation modification are brownish yellow in color. The process of AGEs production is called protein non-enzymatic glycosylation reaction, which is an irreversible reaction. [0003] There are two sources of AGEs in the human body, namely endogenous (produced in vivo) and exogenous (dietary intake). Endogenous AGEs are produced by the g...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P17/00A61K8/9794A61Q19/00A61Q19/02A61Q19/08
CPCA61K36/899A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61Q19/00A61Q19/02A61Q19/08A61K8/9794A61P17/00
Inventor 夏增华徐洁
Owner SUZHOU HEYAN BIOTECH
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