Whitening agent, whitening oil gel containing the same and preparation method thereof

A technology of whitening agent and oil gel, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, cosmetic preparations, etc. It can solve the problems of limited dosage of whitening agents, low transdermal absorption rate, and easy discoloration, etc. Achieve the effect of improving compatibility, good whitening effect, and good whitening effect

Pending Publication Date: 2021-01-26
GUANGZHOU HUANYA COSMETIC SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among the common whitening products on the market, water-based whitening products usually use water-soluble whitening agents such as niacinamide and tranexamic acid as the main functional ingredients. Therefore, the amount of functional ingredients added in water-based whitening products is relatively high, but the types of whitening agents used have certain limitations, and are prone to discoloration under light and high temperature conditions, and the transdermal absorption rate is low; emulsified creams As another common whitening product dosage form on the market, whitening agents have a wide range of choices, and can have water-soluble and oil-soluble whitening agents at the same time. However, due to the low compatibility of emulsifiers, thickeners, etc. The amount of addition is limited to a certain extent, and there are special requirements for the type of packaging materials

Method used

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  • Whitening agent, whitening oil gel containing the same and preparation method thereof
  • Whitening agent, whitening oil gel containing the same and preparation method thereof
  • Whitening agent, whitening oil gel containing the same and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0087] This embodiment provides a whitening agent. The components and respective contents of the whitening agent are shown in Table 1.

[0088] Table 1

[0089] raw material name parts by weight Phenylethylresorcinol 0.5 4-Butylresorcinol 3 Ascorbyl tetraisopalmitate 1 bisabolol 4 Glycyrrhiza glabra root extract 1

[0090] This embodiment also provides a whitening oil gel. The components and respective contents of the whitening oil gel are shown in Table 2.

[0091] Table 2

[0092]

[0093]

[0094] The preparation method of described whitening oil gel comprises the following steps:

[0095] (1) Add sodium stearyl glutamate to the humectant, sonicate at 40°C for 30 minutes, and stir evenly as phase A;

[0096] (2) Heat and dissolve oil, phenylethylresorcinol, 4-butylresorcinol, ascorbyl tetraisopalmitate, bisabolol, hydroxymethyl ester, hydroxypropyl ester and essence at 45°C Uniform, cooled to room temperature, as B phase...

Embodiment 2

[0101] This embodiment provides a whitening agent, and the components and respective contents of the whitening agent are shown in Table 3.

[0102] table 3

[0103]

[0104]

[0105] This embodiment also provides a whitening oil gel. The components and respective contents of the whitening oil gel are shown in Table 4.

[0106] Table 4

[0107]

[0108] The preparation method of described whitening oil gel comprises the following steps:

[0109] (1) Add subtilisin sodium into the humectant, sonicate at 40°C for 10 minutes, and stir evenly as phase A;

[0110] (2) Heat and dissolve oil, phenylethylresorcinol, 4-butylresorcinol, ascorbyl tetraisopalmitate, bisabolol, hydroxymethyl ester, hydroxypropyl ester and essence at 45°C Uniform, cooled to room temperature, as B phase;

[0111] (3) Add nicotinamide into deionized water, stir evenly at room temperature as phase C;

[0112] (4) Under normal temperature and 300rpm stirring conditions, slowly drop phase B into pha...

Embodiment 3

[0115] This embodiment provides a whitening agent, and the components and respective contents of the whitening agent are shown in Table 5.

[0116] table 5

[0117] raw material name parts by weight Phenylethylresorcinol 0.5 4-Butylresorcinol 5 Ascorbyl tetraisopalmitate 1.5 bisabolol 2 Nicotinamide 1

[0118] This embodiment also provides a whitening oil gel, and the components and respective contents of the whitening oil gel are shown in Table 6.

[0119] Table 6

[0120]

[0121]

[0122] The preparation method of described whitening oil gel comprises the following steps:

[0123] (1) Add subtilisin sodium into the humectant, sonicate at 40°C for 15 minutes, and stir evenly as phase A;

[0124] (2) Heat and dissolve oil, phenylethylresorcinol, 4-butylresorcinol, ascorbyl tetraisopalmitate, bisabolol, hydroxymethyl ester, hydroxypropyl ester and essence at 45°C Uniform, cooled to room temperature, as B phase;

[0125] ...

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Abstract

The invention provides a whitening agent, a whitening oil gel containing the same and a preparation method thereof. The whitening agent comprises an oil-soluble whitening agent, and the oil-soluble whitening agent comprises any one or a combination of at least two of phenethyl resorcinol, 4-butyl resorcinol, ascorbyl tetraisopalmitate or bisabolol. The whitening oil gel disclosed by the inventionis transparent in appearance and uniform in texture, has good whitening and freckle-removing effects, and is very high in stability, safety and bioavailability. In the preparation process, ultrasonictreatment is adopted to assist dispersion of the surfactant, which enhances the wrapping capacity of the surfactant on the functional components, and the functional components are prevented from beingdamaged through low-temperature preparation. The preparation method is energy-saving and environmentally friendly, is fast and efficient, and has a wide range of application values.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a whitening agent, a whitening oil gel containing the same and a preparation method thereof. Background technique [0002] With the continuous improvement of people's requirements for beauty, white and smooth skin is praised by more and more women. Therefore, the public's demand for whitening skin care products is increasing day by day, and the sales volume of related products is increasing day by day. [0003] Currently, there are many kinds of whitening products on the market, but they often have the problems of single efficacy, inconspicuous effect and poor permeability. CN108210384A discloses a whitening and freckle-removing skin care product and its preparation method. The raw materials include whitening and freckle-removing additives, component A, component B, component C, component D and purified water, wherein the whitening and freckle-removing additives in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/67A61K8/9789A61Q19/02
CPCA61K8/347A61K8/676A61K8/34A61K8/9789A61K8/675A61Q19/02A61K2800/5922
Inventor 周兆芳胡根华李楚忠陈庆生龚盛昭
Owner GUANGZHOU HUANYA COSMETIC SCI & TECH CO LTD
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