Metformin hydrochloride composition

Abstract

The invention relates to a metformin hydrochloride composition, and belongs to the technical field of pharmacy. The technical scheme is that the metformin hydrochloride composition comprises the following components in parts by weight: 250 parts of metformin hydrochloride, 50-80 parts of soybean phospholipid, 30-50 parts of alginate oligosaccharide, 8-16 parts of hydroxypropyl cellulose, 10-20 parts of aerosil, and 2-4 parts of magnesium stearate. The invention provides the safe and effective metformin hydrochloride composition.

Description

technical field [0001] The invention relates to a metformin hydrochloride composition, which belongs to the technical field of pharmacy. Background technique [0002] Metformin has been used clinically for decades. According to the joint guidelines for the treatment of type 2 diabetes given by the American Diabetes Association and the European Diabetes Association, if there are no special contraindications, patients with type 2 diabetes should take metformin immediately after getting a clear diagnosis, and at the same time carry out lifestyle intervention. As a traditional hypoglycemic drug, metformin is cheap, effective and relatively safe. [0003] Large-scale experiments have proved that metformin only reduces hyperglycemia in diabetic patients, has no effect on physiological blood sugar, and will not cause hypoglycemia when used alone; it can improve insulin sensitivity and promote the utilization of glucose by peripheral tissues; it can delay glucose in the stomach. I...

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to reduce the adverse stimulation of metformin hydrochloride to the gastrointestinal tract and reduce the adverse reactions of patients after taking it.