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Mesenchymal stem cell preparation for treating osteoarthritis as well as preparation method and application

A mesenchymal stem cell and osteoarthritis technology, applied in the field of mesenchymal stem cell preparation and preparation for the treatment of osteoarthritis, can solve the problems of unfavorable clinical promotion and long treatment procedures, and achieve easy expansion and cultivation, strong regeneration and repair capabilities , the effect of reducing the number of injections

Pending Publication Date: 2021-03-26
吉林省熙达生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a mesenchymal stem cell preparation for treating osteoarthritis and its preparation method and application, so as to solve the problem that the treatment procedure in the prior art takes a long time and is not conducive to clinical promotion

Method used

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Examples

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Effect test

Embodiment 1

[0034] This embodiment provides a mesenchymal stem cell preparation for treating osteoarthritis. The raw materials for preparing the mesenchymal stem cell preparation include sodium hyaluronate, platelet-rich plasma, mesenchymal stem cells, glucosamine and chondroitin sulfate. The parts by volume are 5 parts of sodium hyaluronate, 1 part of platelet-rich plasma, 2 parts of mesenchymal stem cells, 1 part of glucosamine, and 1 part of chondroitin sulfate.

[0035] The mesenchymal stem cell preparation provided in this example is used for those with no cartilage damage or slight damage and no or a small amount of joint cavity effusion in osteoarthritis.

Embodiment 2

[0037] This embodiment provides a mesenchymal stem cell preparation for treating osteoarthritis. The raw materials for preparing the mesenchymal stem cell preparation include sodium hyaluronate, platelet-rich plasma, mesenchymal stem cells, glucosamine and chondroitin sulfate. The parts by volume are 1 part of sodium hyaluronate, 2 parts of platelet-rich plasma, 5 parts of mesenchymal stem cells, 1 part of glucosamine, and 1 part of chondroitin sulfate.

[0038] The mesenchymal stem cell preparation provided in this example is used for osteoarthritis patients with mild pain caused by cartilage defect and no or a small amount of joint cavity effusion.

Embodiment 3

[0040] This embodiment provides a mesenchymal stem cell preparation for treating osteoarthritis. The raw materials for preparing the mesenchymal stem cell preparation include sodium hyaluronate, platelet-rich plasma, mesenchymal stem cells, glucosamine and chondroitin sulfate. The parts by volume are 2 parts of sodium hyaluronate, 5 parts of platelet-rich plasma, 1 part of mesenchymal stem cells, 1 part of glucosamine, and 1 part of chondroitin sulfate.

[0041] The mesenchymal stem cell preparation provided in this example is used for osteoarthritis patients with cartilage or meniscus damage, mild to moderate pain, and no joint cavity effusion.

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Abstract

The invention provides a mesenchymal stem cell preparation for treating osteoarthritis as well as a preparation method and application. The mesenchymal stem cell preparation for treating osteoarthritis is prepared from the following raw materials: sodium hyaluronate, platelet-rich plasma, mesenchymal stem cells, glucosamine and chondroitin sulfate. According to the mesenchymal stem cell preparation for treating osteoarthritis, sodium hyaluronate with an exact lubricating effect is combined with platelet-rich plasma having an exact cartilage regeneration and repair promoting capability, the mesenchymal stem cells which have living activity, can be differentiated in multiple directions and have strong regeneration and repair capabilities are added, and by matching other biological reagents,a mixed biological product is prepared, and can be applied to a treatment part at a time, the course of disease can be shortened to 5 weeks and reduced by 10 weeks, the application dosage is accurate,the injection frequency of a patient is reduced by 2 / 3, and the preparation is a treatment method which is beneficial to both doctors and patients.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to a mesenchymal stem cell preparation for treating osteoarthritis, a preparation method and application thereof. Background technique [0002] Osteoarthritis is a kind of degenerative disease, which is a common and high-incidence disease among senile diseases. At present, it has generally stepped into the aging society, and the number of patients with osteoarthritis is close to 100 million. The number of patients is increasing. Among them, the damage of articular cartilage is irreversible. At present, traditional Chinese medicine, physical therapy, drug therapy, and closed therapy are the mainstream methods for the conventional treatment of osteoarthritis, but the curative effect is not satisfactory, and the long-term curative effect is even worse. Sodium hyaluronate is also used. Intra-articular injections, platelet-rich plasma intra-articular injections, and various cell regeneratio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/51A61K9/00C12N5/0775A61K35/16A61K35/19A61P19/00A61P19/02A61P29/00A61K31/7008A61K31/728A61K31/737
CPCA61K35/51A61K31/728A61K31/737A61K31/7008A61K35/16A61K35/19A61K9/0019A61P19/02A61P19/00A61P29/00C12N5/0665C12N2500/90C12N2509/00C12N2509/10A61K2300/00
Inventor 于英
Owner 吉林省熙达生物科技有限公司
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