Application of pennoside compound
A technology of pinanoside and compound, applied in the field of medicine
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[0036] The present invention is further described below by examples, but the present invention is not limited by these examples. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.
[0037] The invention provides a pinanoside compound having a structure of formula (1) and the application of a pharmaceutically acceptable salt thereof in the preparation of a medicine for treating rheumatoid arthritis;
[0038]
[0039] Wherein, R is H or a sugar chain.
[0040] The pinenoside compound can be Paris saponin VII or Pennogenin 3β-O-α-L-rhamnopyranosyl-(1→4)-[-O-α-L-rhamnopyranosyl-(1→2)]-O-β- D-glucopyranoside can also be Paris saponin VI.
[0041] The pinanoside compound can reduce the proliferation of RA-FLS and MH7A synoviocytes, and trigger the apoptosis of RA-FLS and MH7A synoviocytes, and can be used to prepare drugs for reducing th...
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