Method and device for predicting the effect of vitrification and recovery of human mature oocytes

Abstract

This application relates to a method and device for predicting the effect of vitrification and recovery of human mature oocytes. The prediction method includes obtaining the basic information of the woman, the number of large and medium follicles in the application of follicle-stimulating drugs, test results of sex hormones, and infertility-related diseases. The results, as well as the man's semen test results; calculate the predicted probability P of no embryo transfer for the proposed egg cell cryopreservation operation 1 and the cumulative predicted probability of live birth P 2 ;according to P 1 and P 2 The numerical value predicts recovery effect. The forecasting device includes a memory, a processor, and a computer program stored in the memory and operable on the processor. The above-mentioned forecasting method is realized when the processor executes the computer program. This application estimates the recovery effect of the planned egg cell cryopreservation operation through the clinical history data and laboratory test results of the couple before egg retrieval, helps patients make reasonable decisions, minimizes the risk of unnecessary surgical operations and avoids Waste of time and medical resources.

Description

technical field [0001] The invention relates to the technical field of human assisted reproduction, more specifically, it relates to a method and a device for predicting the vitrification recovery effect of human mature oocytes. Background technique [0002] Assisted reproductive technology refers to the use of medical assistance to make infertile couples pregnant. Delayed childbearing age, environmental pollution, increased work pressure and other reasons make more and more couples need the help of assisted reproductive technology, and oocyte freezing is one of the important assisted reproductive technologies. [0003] During the IVF-ET treatment, if the man is unable to come to the hospital to collect sperm due to sudden illness or accident, masturbation or surgical sperm retrieval failure, or other unexpected sperm retrieval failures, or does not obtain enough sperm for assisted fertility treatment on the day of egg retrieval Emergency oocyte freezing for sperm, etc. ...

AI Technical Summary

Problems solved by technology

[0004] The characteristics of oocytes themselves determine that they are extremely vulnerable to freezing damage, and may not be able to form embryos after thawing, and the oocyte retrieval operation itself has risks such as bleeding and infection, which will cause physical and mental harm to patients; on the other hand, if you give up Egg retrieval, the cost and time wasted in the process of early ovulation induction, and the super-physiological dose of estrogen in the body lead to a significant increase in the risk of ovarian hyperstimulation syndrome

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