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Traditional Chinese medicine composition for preventing or treating diabetic encephalopathy and application thereof

A technology of diabetic encephalopathy and composition, applied in the field of traditional Chinese medicine, can solve problems such as incomplete treatment of diabetic encephalopathy and lack of treatment methods

Pending Publication Date: 2021-09-10
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, the current traditional Chinese medicine is not comprehensive for the treatment of diabetic encephalopathy, and there is a lack of effective treatment methods.

Method used

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  • Traditional Chinese medicine composition for preventing or treating diabetic encephalopathy and application thereof
  • Traditional Chinese medicine composition for preventing or treating diabetic encephalopathy and application thereof
  • Traditional Chinese medicine composition for preventing or treating diabetic encephalopathy and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] A composition for preventing or treating diabetic encephalopathy, which is made of the following raw materials: 20 parts of Zhimu, 20 parts of Cortex Phellodendri, and 20 parts of Cistanche.

[0058] The preparation method is:

[0059] Weigh the above raw materials, according to the ratio of 1g:10mL, add 80% ethanol aqueous solution to the raw materials, heat to reflux, filter, extract twice, each time 2h, combine the filtrates, and concentrate to 1.5g / mL.

Embodiment 2

[0061] A composition for preventing or treating diabetic encephalopathy, which is made from the following raw materials: 10 parts of Anemarrhena, 20 parts of Cortex Phellodendri, and 20 parts of Cistanche.

[0062] The above-mentioned raw materials are pulverized and passed through an 80-mesh sieve to make a powder.

Embodiment 3

[0064] A pharmaceutical composition for preventing or treating diabetic encephalopathy, which is prepared from the following raw materials: 35 parts of Zhimu, 20 parts of Cortex Phellodendri, and 5 parts of Cistanche.

[0065] Weigh the above raw materials, add 10 times the amount of water to the raw materials, heat to reflux, filter, extract twice for 1.5 hours each time, combine the filtrates, concentrate and dry, and add dextrin to make granules.

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing or treating diabetic encephalopathy and application thereof. The traditional Chinese medicine composition is prepared from rhizoma anemarrhenae, cortex phellodendri and herba cistanche. The traditional Chinese medicine composition can obviously improve diabetic encephalopathy hippocampal injury, inhibit activation of microglial cells in a hippocampal region, reduce diabetic cerebrovascular and nerve cell injury, enhance an intracerebral lymphatic system clearing function, increase the number and stability of cerebrovascular neogenesis and reduce small intestine mucosa injury.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for preventing or treating diabetic encephalopathy. Background technique [0002] Traditional medicine believes that the basic pathogenesis of diabetes is mainly due to the deficiency of yin and fluid, and the excess of dryness and heat. Qing Chen Shiduo pointed out in "Stone Chamber Secret Records Diabetes Syndrome and Treatment": "Although the symptoms of diabetes can be divided into upper, middle and lower, there is no difference between kidney deficiency and thirst." , originally it was activated, and this is caused by kidney deficiency." "Yan's Jisheng Fang Xiaokemen" said: "The disease of quenching thirst all starts in the kidney." Diabetic encephalopathy is closely related to TCM diabetes combined with dementia. In recent years, the impact of diabetes on the central nervous system has gradually attracted pe...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P3/10A61P25/00A61P25/28A61P29/00A61P1/00
CPCA61K36/8964A61K36/756A61K36/64A61P3/10A61P25/00A61P25/28A61P29/00A61P1/00A61K2236/331A61K2236/333A61K2300/00
Inventor 庄朋伟张艳军尹清晟杨珍王艳
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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