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Porcupine thorn animal medicine as well as preparation method and application thereof

A technology for animal medicine and ointment, which is applied in the directions of pharmaceutical formulations, drug combinations, and medical preparations containing active ingredients, and can solve problems such as unseen patent solutions

Pending Publication Date: 2021-09-14
KAILI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

After searching, there is no patent solution for the treatment of diabetic foot with porcupine spines animal medicine

Method used

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  • Porcupine thorn animal medicine as well as preparation method and application thereof
  • Porcupine thorn animal medicine as well as preparation method and application thereof
  • Porcupine thorn animal medicine as well as preparation method and application thereof

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Embodiment Construction

[0029] Below by example and accompanying drawing, the present invention will be further described.

[0030] A porcupine thorn animal medicine is prepared by crushing porcupine thorns into powder, extracting with ethanol, extracting with petroleum ether, concentrating to fluid extract, volatilizing to dry extract, grinding into fine powder, and then making ointment.

[0031] The preparation method of described a kind of porcupine spines animal medicine is as follows:

[0032] Cut the purchased porcupine spines to 3-4cm, process them with sand until the appearance is slightly yellow, mash them with a high-speed universal grinder, and pass through a 60-100 mesh sieve. The ratio of feeding liquid is 1:10-1:20g / mL, and the concentration is 50- Reflux extraction with 90% ethanol for 30-60min, twice in total, filter and combine the filtrate, extract 3 times with petroleum ether at a volume ratio of 1:1-1:5, combine the extracts, and concentrate in a rotary evaporator to liquid extrac...

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Abstract

The invention discloses a porcupine thorn animal medicine. The porcupine thorn animal medicine is prepared by the following steps: cutting purchased porcupine thorn to 3-4 cm, adding sand, processing until the surface is yellowish, mashing by using a high-speed universal pulverizer, sieving by using a 60-100-mesh sieve, carrying out reflux extraction for 30-60 minutes by using 50-90% ethanol in a feed liquid ratio of (1: 10)-(1: 20) g / mL twice in total, filtering and combining the filtrate, extracting for 3 times by using petroleum ether in a volume ratio of (1: 1)-(1: 5), combining the extract liquor, concentrating in a rotary evaporator to obtain a fluid extract, drying the fluid extract in a water bath kettle at the temperature of 80 DEG C, grinding the dry extract into superfine powder, adding sesame oil to prepare ointment with the mass concentration of 0.2-1.0 g / mL, sterilizing for 30 minutes under an ultraviolet lamp, and sealing and refrigerating. The porcupine thorn animal medicine can effectively reduce the exudate of the wound surface of burn and scald or diabetic foot, shorten the scabbing time of the wound surface, improve the healing rate of the wound surface, and provide experimental basis for popularization and use of porcupine thorn in clinical treatment of burn and scald or diabetic foot and screening of potential pharmacodynamic substances.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine animal medicine, in particular to a porcupine spine animal medicine and its preparation method and application. Background technique [0002] Porcupine thorns are the dried spines of Hystrix hodgsoni Gray [Hystrix hodgsoni subcristata (Swinhoe) [Hystrix hodgsoni papae (GAlen)], Hystrix brachyuran. Linaeus [Hystrix brachyuran yunnanensis Anderson.] This product was first recorded in "Compendium of Materia Medica". The thorns (burrs) are sweet and smelly, and have great cold, promote qi and relieve pain, detoxify and reduce swelling. Cold, moistens the intestines and laxatives, and mainly treats poor stool. Modern studies have shown that Porcupine Pork Ganmeiduo Ointment is high in protein and low in fat, and enjoys the reputation of "ginseng" in meat. Its thorns (porcupine thorns or Suge hairs or thorny pig hairs), in addition to making buoys and handicrafts, have great potential for m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/36A61K9/06A61K47/44A61P17/02A61P3/10
CPCA61K35/36A61K9/06A61K47/44A61P17/02A61P3/10
Inventor 周邦华王翔张富祥赖先荣李小让石懿余丽琼
Owner KAILI UNIV
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