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Flm coating agent for disinfection based on polyhexamethylene guanidine and preparation method thereof

A technology of polyhexamethyleneguanidine and film-coating agent, which is applied in the direction of non-active ingredient medical preparations, active ingredient-containing medical preparations, antifungal agents, etc. It can solve the problems of not yet providing film-forming preparations, etc., and achieve Expanded bactericidal and antiviral effects, rapid bactericidal, and long-lasting effects

Pending Publication Date: 2021-10-01
潮州市亿生健医药保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the prior art has not yet provided a film-forming formulation capable of rapid sterilization and sustained bacteriostasis

Method used

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  • Flm coating agent for disinfection based on polyhexamethylene guanidine and preparation method thereof
  • Flm coating agent for disinfection based on polyhexamethylene guanidine and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0025] Add 10 grams of polyvinyl butyral (PVB) to 80 grams of ethanol, stir and dissolve, then add 3.0 grams of triethyl citrate and stir to dissolve to make solution 1; Add 5 grams of mixed extracts of Sophora flavescens, Fructus Cnidii, Rhubarb, Fructus Kochia and Centipeda, 10 grams of glycerin in the refined water, stir to dissolve, and make solution 2; add solution 2 to solution 1 and stir evenly, Make up the remaining amount of purified water to 100 grams to obtain a disinfectant coating agent combining polyhexamethyleneguanidine and traditional Chinese medicine extract.

Embodiment 2

[0027] Add 3 grams of ethylene-vinyl acetate copolymer (EVA) to 80 grams of ethanol, stir to dissolve, then add 4 grams of acetyl tributyl citrate to make solution 1; take 0.5 grams of polyhexamethylene guanidine in 5 Add 5 grams of mixed extracts of Sophora flavescens, Fructus Cnidii Fructus, rhubarb, Fructus Kochia and Centipeda, 10 grams of propylene glycol, and stir to dissolve in 1 g of refined water to make solution 2; add solution 2 to solution 1 and stir evenly, Make up the remaining amount of purified water to 100 grams to obtain a disinfectant coating agent combining polyhexamethyleneguanidine and traditional Chinese medicine extract.

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Abstract

The invention provides a film coating agent for disinfection based on polyhexamethylene guanidine and a preparation method thereof. The formula of the film coating agent for disinfection based on polyhexamethylene guanidine is as follows: 0.25-0.5 of polyhexamethylene guanidine; 0.1-5.0 parts of a traditional Chinese medicinal material extract; 5.0-15.0 parts of a film forming material; 2.0-4.0 parts of a plasticizer; 10-15 parts of a humectant / pore-foaming agent; 20-75 parts of ethanol; and the balance of refined water. The film coating agent for disinfection based on polyhexamethylene guanidine is a compound disinfection film coating agent formed by multiple components, the sterilization and antiviral effects can be expanded, the film forming characteristic of a film forming material is utilized, a layer of water-insoluble protective film can be formed when the film coating agent is coated on an arm, the film coating agent has the effect of an invisible glove, meanwhile, a humectant / pore-foaming agent is added, the physiological function of skin and the normal work of fingers are not influenced, and the film coating agent has the characteristics of quick sterilization and long maintenance time.

Description

technical field [0001] The invention belongs to the technical field of film-coating agents, in particular to a film-coating agent for disinfection based on polyhexamethyleneguanidine and a preparation method thereof. Background technique [0002] A dosage form in pharmacy - film-coating agent, which refers to an external preparation in which the drug is dissolved or dispersed in the solvent of the film-forming material and applied to the affected area to form a thin film. When used, it is applied to the affected area, and a thin film is formed after the solvent volatilizes, which has a protective effect on the affected area, and at the same time gradually releases the contained medicine to play a therapeutic effect. Environmentally friendly polymer bactericidal disinfectant - polyhexamethylene guanidine, has the excellent properties of broad-spectrum sterilization, quick-acting, low effective concentration, fast action speed, stable properties, and easy solubility in water; ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K31/785A61K36/904A61K47/10A61K47/32A61P31/02A61P31/04A61P31/10
CPCA61K31/785A61K36/489A61K36/234A61K36/708A61K36/185A61K36/904A61K9/7015A61K47/32A61K47/10A61P31/02A61P31/04A61P31/10A61K2300/00
Inventor 房志仲林培鸿
Owner 潮州市亿生健医药保健品有限公司
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